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Vaccine Detail

Prostate cancer DNA vaccine pDOM-PSMA27 encoding PSMA
Vaccine Information
  • Vaccine Name: Prostate cancer DNA vaccine pDOM-PSMA27 encoding PSMA
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Vaccine Ontology ID: VO_0007145
  • Type: DNA vaccine
  • Status: Research
  • Host Species as Laboratory Animal Model: Human
  • Prostate-specific membrane antigen gene engineering:
    • Type: DNA vaccine construction
    • Description: This DNA vaccine expressed prostate-specific membrane antigen (PSMA) (Chudley et al., 2012).
    • Detailed Gene Information: Click Here.
  • Immunization Route: Intramuscular injection (i.m.)
  • Description: This is for Prostate Cancer.
Host Response
References
Chudley et al., 2012: Chudley L, McCann K, Mander A, Tjelle T, Campos-Perez J, Godeseth R, Creak A, Dobbyn J, Johnson B, Bass P, Heath C, Kerr P, Mathiesen I, Dearnaley D, Stevenson F, Ottensmeier C. DNA fusion-gene vaccination in patients with prostate cancer induces high-frequency CD8(+) T-cell responses and increases PSA doubling time. Cancer immunology, immunotherapy : CII. 2012; ; . [PubMed: 22729556].