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Vaccine Detail

Glypican-3-derived peptide vaccine for human hepatocellular carcinoma
Vaccine Information
  • Vaccine Name: Glypican-3-derived peptide vaccine for human hepatocellular carcinoma
  • Target Pathogen: Cancer
  • Target Disease: Cancer
  • Vaccine Ontology ID: VO_0004400
  • Type: Subunit vaccine
  • Status: Clinical trial
  • Antigen: A peptide from carcinoembryonic antigen glypican-3 (GPC3) (Sawada et al., 2012)
  • Immunization Route: Intramuscular injection (i.m.)
Host Response
References
Sawada et al., 2012: Sawada Y, Yoshikawa T, Nobuoka D, Shirakawa H, Kuronuma T, Motomura Y, Mizuno S, Ishii H, Nakachi K, Konishi M, Nakagohri T, Takahashi S, Gotohda N, Takayama T, Yamao K, Uesaka K, Furuse J, Kinoshita T, Nakatsura T. Phase I Trial of a Glypican-3-Derived Peptide Vaccine for Advanced Hepatocellular Carcinoma: Immunologic Evidence and Potential for Improving Overall Survival. Clinical cancer research : an official journal of the American Association for Cancer Research. 2012; 18(13); 3686-3696. [PubMed: 22577059].