• Vaccine Name: Tripedia
• Target Pathogen: Corynebacterium diphtheriae
• Target Disease: Diphtheria
• Product Name: Diphtheria and Tetanus Toxoids and Acellular Pertussis Vaccine Adsorbed
• Tradename: Tripedia
• Manufacturer: Sanofi Pasteur, Inc.
• Vaccine Ontology ID: VO_0000112
• CDC CVX code: 20
• Type: Toxoid vaccine
• Status: Licensed
• Location Licensed: USA (License #1725)
• Host Species for Licensed Use: Human
• Adjuvant:
  • Adjuvant name:
  • VO adjuvant ID: VO_0001240
  • Description: Tripedia vaccine combines diptheria and tetanus toxoids with purified pertussis antigens. It consists of 3 doses administered at intervals of 4-8 weeks (FDA: Tripedia).
• Preparation: Corynebacterium diphtheriae cultures are grown in a modified Mueller and Miller medium. It is detoxified with formaldehyde and then seperately purified by serial ammonium sulfate fractionation and diafiltration (FDA: Tripedia).
• Immunization Route: Intramuscular injection (i.m.)
• Storage: Store between 2 and 8 degrees Celsius. DO NOT FREEZE.
• Approved Age for Licensed Use: Tripedia vaccine is indicated for active immunization against diphtheria, tetanus, and pertussis simultaneously in infants and children 6 weeks to 7 years of age (prior to seventh birthday) (FDA: Tripedia).
• Contraindication: This vaccine should not be administered to anyone with a known hypersensitivity to any component of the vaccine.
• Description: Tripedia vaccine combines diptheria and tetanus toxoids with purified pertussis antigens. It consists of 3 doses administered at intervals of 4-8 weeks (FDA: Tripedia).

Human Response

• Side Effects: Side effects of vaccination include: injection site reactions, fevver, irritability, drowsiness, and vomiting. In some cases with infant immunization, anorexia and an unusual hig-pitched cry were reported (FDA: Tripedia).
• Efficacy: Complete immunization significantly reduces the risk of developing diptheria and protection lasts around 10 years.