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Vaccine Detail

HIV recombinant vector vaccine MVA.HIVA encoding env and rev

Vaccine Information

Vaccine Name: HIV recombinant vector vaccine MVA.HIVA encoding env and rev
Target Pathogen: Human Immunodeficiency Virus
Target Disease: Acquired Immunodeficiency Syndrome (AIDS)
Vaccine Ontology ID: VO_0004350
Type: Recombinant vector vaccine
Status: Research
Host Species as Laboratory Animal Model: Human
env gene engineering:
- Type: Recombinant vector construction
- Description: This DNA vaccine encoded env from HIV-1 (Peters et al., 2007).
- Detailed Gene Information: Click Here.
rev from HIV 1 gene engineering:
- Type: Recombinant vector construction
- Description: This DNA vaccine expressed rev from HIV-1 (Peters et al., 2007).
- Detailed Gene Information: Click Here.
Immunization Route: Intramuscular injection (i.m.)

Host Response

References

Peters et al., 2007: Peters BS, Jaoko W, Vardas E, Panayotakopoulos G, Fast P, Schmidt C, Gilmour J, Bogoshi M, Omosa-Manyonyi G, Dally L, Klavinskis L, Farah B, Tarragona T, Bart PA, Robinson A, Pieterse C, Stevens W, Thomas R, Barin B, McMichael AJ, McIntyre JA, Pantaleo G, Hanke T, Bwayo J. Studies of a prophylactic HIV-1 vaccine candidate based on modified vaccinia virus Ankara (MVA) with and without DNA priming: effects of dosage and route on safety and immunogenicity. Vaccine. 2007; 25(11); 2120-2127. [PubMed: 17250931].