• Vaccine Name: Lymphocytic choriomeningitis virus DNA vaccine pCMV-NP
• Target Pathogen: Lymphocytic choriomeningitis virus
• Target Disease: Lymphocytic choriomeningitis
• Vaccine Ontology ID: VO_0004327
• Type: DNA vaccine
• Status: Research
• Host Species as Laboratory Animal Model: Mouse
• NP gene engineering:
  • Type: DNA vaccine construction
  • Description: This DNA vaccine encodes the full-length LCMV Armstrong nucleoprotein (Hassett et al., 2000).
  • Detailed Gene Information: Click Here.
• DNA vaccine plasmid:
  • DNA vaccine plasmid name:
  • DNA vaccine plasmid VO ID: VO_0000215
• Immunization Route: Intramuscular injection (i.m.)

Mouse Response

• Vaccine Immune Response Type: VO_0000286
• Efficacy: Mice were injected i.m. with pCMV-NP, which was shown to protect from intracranial LCMV challenge (Hassett et al., 2000).