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Vaccine Detail
Influenza virus DNA vaccine A/NP |
Vaccine Information |
- Vaccine Name: Influenza virus DNA vaccine A/NP
- Target Pathogen: Influenza virus
- Target Disease: Influenza (flu)
- Vaccine Ontology ID: VO_0004307
- Type: DNA vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse
- NP
gene engineering:
- Type: DNA vaccine construction
- Description: Vector VR1012 expressed NP (Epstein et al., 2005).
- Detailed Gene Information: Click Here.
- DNA vaccine plasmid:
- DNA vaccine plasmid name:
- DNA vaccine plasmid VO ID: VO_0000334
- Immunization Route: Intramuscular injection (i.m.)
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Host Response |
Mouse Response
- Vaccination Protocol: DNA prime-recombinant adenoviral boost immunization to nucleoprotein (NP) (Epstein et al., 2005).
- Vaccine Immune Response Type: VO_0000286
- Efficacy: Vaccination protected against lethal challenge with highly pathogenic H5N1 virus (Epstein et al., 2005).
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References |
Epstein et al., 2005: Epstein SL, Kong WP, Misplon JA, Lo CY, Tumpey TM, Xu L, Nabel GJ. Protection against multiple influenza A subtypes by vaccination with highly conserved nucleoprotein. Vaccine. 2005; 23(46-47); 5404-5410. [PubMed: 16011865].
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