• Vaccine Name: Salmonella Typhimurium cya/crp mutant vaccine
• Target Pathogen: Salmonella spp.
• Target Disease: Salmonellosis
• Type: Live, attenuated vaccine
• Status: Research
• Host Species as Laboratory Animal Model: Mouse
• crp from S. Typhimurium gene engineering:
  • Type: Gene mutation
  • Description: This crp mutant is from S. Typhimurium (Curtiss and Kelly, 1987).
  • Detailed Gene Information: Click Here.
• cya gene engineering:
  • Type: Gene mutation
  • Description: This cya mutant is from S. Typhimurium (Curtiss and Kelly, 1987).
  • Detailed Gene Information: Click Here.
• Immunization Route: Peroral Inoculation

Mouse Response

• Persistence: A cya and crp mutant is attenuated in mice (Curtiss and Kelly, 1987).
• Efficacy: Thirty days after immunization, mice were protected from oral challenge with wild type S. typhimurium (Curtiss and Kelly, 1987).