• Vaccine Name: Borrelia burgdorferi fla mutant vaccine
• Target Pathogen: Borrelia burgdorferi
• Target Disease: Lyme Disease
• Vaccine Ontology ID: VO_0002809
• Type: Live, attenuated vaccine
• Status: Research
• Host Species as Laboratory Animal Model: Mouse
• fla gene engineering:
  • Type: Gene mutation
  • Description: This fla mutant is from Borrelia burgdorferi (Sadziene et al., 1996).
  • Detailed Gene Information: Click Here.
• Immunization Route: Intradermal injection (i.d.)

Mouse Response

• Persistence: A fla mutant is attenuated in SCID mice (Sadziene et al., 1996).
• Efficacy: A fla mutant induces protection in mice from challenge with wild type B. burgdorferi 28 days after inoculation (Sadziene et al., 1996).