|
|
Vaccine Detail
|
Classical swine fever virus E2 mutant vaccine |
| Vaccine Information |
- Vaccine Name: Classical swine fever virus E2 mutant vaccine
- Target Pathogen: Classical swine fever virus
- Target Disease: Classical swine fever, hog cholera
- Vaccine Ontology ID: VO_0002954
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Pig
- E2
gene engineering:
- Type: Gene mutation
- Description: This E2 mutant is from Classical swine fever virus (Maurer et al., 2005).
- Detailed Gene Information: Click Here.
- Immunization Route: Oronasal immunization
|
| Host Response |
|
Pig Response
- Persistence: An E2 mutant is attenuated in swine (Maurer et al., 2005).
- Efficacy: An E2 mutant induced significant protection in swine from challenge with wild type CSFV (Maurer et al., 2005).
|
| References |
Maurer et al., 2005: Maurer R, Stettler P, Ruggli N, Hofmann MA, Tratschin JD. Oronasal vaccination with classical swine fever virus (CSFV) replicon particles with either partial or complete deletion of the E2 gene induces partial protection against lethal challenge with highly virulent CSFV. Vaccine. 2005; 23(25); 3318-3328. [PubMed: 15837238].
|
|
