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Vaccine Detail
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Classical swine fever virus E(rns) mutant vaccine |
| Vaccine Information |
- Vaccine Name: Classical swine fever virus E(rns) mutant vaccine
- Target Pathogen: Classical swine fever virus
- Target Disease: Classical swine fever, hog cholera
- Vaccine Ontology ID: VO_0002952
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Pig
- E(rns)
gene engineering:
- Type: Gene mutation
- Description: This E(rns) mutant is from Classical swine fever virus (Sainz et al., 2008).
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
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| Host Response |
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Pig Response
- Persistence: An E(rns) mutant is attenuated in swine (Sainz et al., 2008).
- Efficacy: An E(rns) mutant induces protection in swine from challenge with wild type CSVF (Sainz et al., 2008).
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| References |
Sainz et al., 2008: Sainz IF, Holinka LG, Lu Z, Risatti GR, Borca MV. Removal of a N-linked glycosylation site of classical swine fever virus strain Brescia Erns glycoprotein affects virulence in swine. Virology. 2008; 370(1); 122-129. [PubMed: 17904607].
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