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Vaccine Detail
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Escherichia coli carAB mutant vaccine |
| Vaccine Information |
- Vaccine Name: Escherichia coli carAB mutant vaccine
- Target Pathogen: Escherichia coli
- Target Disease: Hemorrhagic colitis
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Turkey
- carA
gene engineering:
- Type: Gene mutation
- Description: This carAB mutant is from Escherichia coli (Kwaga et al., 1994).
- Detailed Gene Information: Click Here.
- carB
gene engineering:
- Type: Gene mutation
- Description: This carAB mutant is from Escherichia coli (Kwaga et al., 1994).
- Detailed Gene Information: Click Here.
- Immunization Route: Oral immunization
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| Host Response |
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Turkey Response
- Persistence: A carAB mutant is attenuated in turkeys (Kwaga et al., 1994).
- Efficacy: A carAB mutant induces significant protection in turkeys from challenge with wild type E. coli (Kwaga et al., 1994).
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| References |
Kwaga et al., 1994: Kwaga JK, Allan BJ, van der Hurk JV, Seida H, Potter AA. A carAB mutant of avian pathogenic Escherichia coli serogroup O2 is attenuated and effective as a live oral vaccine against colibacillosis in turkeys. Infection and immunity. 1994; 62(9); 3766-3772. [PubMed: 8063392].
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