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Vaccine Detail
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Gallid herpesvirus 1 UL0 mutant vaccine |
| Vaccine Information |
- Vaccine Name: Gallid herpesvirus 1 UL0 mutant vaccine
- Target Pathogen: Gallid herpesvirus 1
- Target Disease: Avian infectious laryngotracheitis, Fowl Laryngotracheitis
- Vaccine Ontology ID: VO_0002966
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Chicken
- UL0
gene engineering:
- Type: Gene mutation
- Description: This UL0 mutant is from Gallid herpesvirus 1 (Veits et al., 2003).
- Detailed Gene Information: Click Here.
- Immunization Route: Eye drop
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| Host Response |
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Chicken Response
- Persistence: A UL0 mutant is attenuated in chickens (Veits et al., 2003).
- Efficacy: A UL0 mutant induces significant protection in chickens from challenge with wild type gallid herpesvirus 1 (Veits et al., 2003).
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| References |
Veits et al., 2003: Veits J, Lüschow D, Kindermann K, Werner O, Teifke JP, Mettenleiter TC, Fuchs W. Deletion of the non-essential UL0 gene of infectious laryngotracheitis (ILT) virus leads to attenuation in chickens, and UL0 mutants expressing influenza virus haemagglutinin (H7) protect against ILT and fowl plague. The Journal of general virology. 2003; 84(Pt 12); 3343-3352. [PubMed: 14645915].
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