• Vaccine Name: Mannheimia haemolytica aroA mutant vaccine
• Target Pathogen: Mannheimia haemolytica
• Target Disease: Bovine Respiratory Disease
• Vaccine Ontology ID: VO_0002856
• Type: Live, attenuated vaccine
• Status: Research
• Host Species as Laboratory Animal Model: Mouse
• aroA gene engineering:
  • Type: Gene mutation
  • Description: This aroA mutant is from Mannheimia haemolytica (Homchampa et al., 1994).
  • Detailed Gene Information: Click Here.
• Immunization Route: Intraperitoneal injection (i.p.)

Mouse Response

• Persistence: An aroA mutant is attenuated in mice (Homchampa et al., 1994).
• Efficacy: An aroA mutant induced significant protection in mice from challenge with wild type M. haemolytica (Homchampa et al., 1994).