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Vaccine Detail
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P. yoelii p36/p52 mutant vaccine |
| Vaccine Information |
- Vaccine Name: P. yoelii p36/p52 mutant vaccine
- Target Pathogen: Plasmodium spp.
- Target Disease: Malaria
- Vaccine Ontology ID: VO_0003009
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse
- Py36
gene engineering:
- Type: Gene mutation
- Description: This p36/p52 mutant is from Plasmodium yoelii (Labaied et al., 2007).
- Detailed Gene Information: Click Here.
- Py52
gene engineering:
- Type: Gene mutation
- Description: This p36/p52 mutant is from Plasmodium yoelii (Labaied et al., 2007).
- Detailed Gene Information: Click Here.
- Immunization Route: Intravenous injection (i.v.)
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| Host Response |
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Mouse Response
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| References |
Labaied et al., 2007: Labaied M, Harupa A, Dumpit RF, Coppens I, Mikolajczak SA, Kappe SH. Plasmodium yoelii sporozoites with simultaneous deletion of P52 and P36 are completely attenuated and confer sterile immunity against infection. Infection and immunity. 2007; 75(8); 3758-3768. [PubMed: 17517871].
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