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Vaccine Detail
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Pseudorabies virus UL50 mutant vaccine |
| Vaccine Information |
- Vaccine Name: Pseudorabies virus UL50 mutant vaccine
- Target Pathogen: Pseudorabies virus
- Target Disease: Aujeszky's disease
- Vaccine Ontology ID: VO_0002989
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Pig
- UL50
gene engineering:
- Type: Gene mutation
- Description: This UL50 mutant is from Suid herpesvirus 1 (Jöns et al., 1997).
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
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| Host Response |
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Pig Response
- Persistence: A UL50 mutant is attenuated in pigs (Jöns et al., 1997).
- Efficacy: A UL50 mutant induces protection in pigs from challenge with wild type Pseudorabies virus (Jöns et al., 1997).
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| References |
Jöns et al., 1997: Jöns A, Gerdts V, Lange E, Kaden V, Mettenleiter TC. Attenuation of dUTPase-deficient pseudorabies virus for the natural host. Veterinary microbiology. 1997; 56(1-2); 47-54. [PubMed: 9228681].
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