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Vaccine Detail
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Psuedorabies virus glycoprotein M mutant vaccine |
| Vaccine Information |
- Vaccine Name: Psuedorabies virus glycoprotein M mutant vaccine
- Target Pathogen: Pseudorabies virus
- Target Disease: Aujeszky's disease
- Vaccine Ontology ID: VO_0002985
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Pig
- glycoprotein M
gene engineering:
- Type: Gene mutation
- Description: This glycoprotein M mutant is from Pseudorabies virus (Dijkstra et al., 1997).
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
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| Host Response |
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Pig Response
- Persistence: A glycoprotein M mutant is attenuated in piglets (Dijkstra et al., 1997).
- Efficacy: A glycoprotein M mutant induces protection in piglets from challenge with wild type Pseudorabies virus (Dijkstra et al., 1997).
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| References |
Dijkstra et al., 1997: Dijkstra JM, Gerdts V, Klupp BG, Mettenleiter TC. Deletion of glycoprotein gM of pseudorabies virus results in attenuation for the natural host. The Journal of general virology. 1997; 78 ( Pt 9); 2147-2151. [PubMed: 9292000].
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