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Vaccine Detail
Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine |
Vaccine Information |
- Vaccine Name: Pseudorabies virus glycoprotein E/G/UL23 mutant vaccine
- Target Pathogen: Pseudorabies virus
- Target Disease: Aujeszky's disease
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Raccoon
- glycoprotein G
gene engineering:
- Type: Gene mutation
- Description: This glycoprotein E/G/UL23 mutant is from Suid herpesvirus 1 (Weigel et al., 2003).
- Detailed Gene Information: Click Here.
- glycoprotein E
gene engineering:
- Type: Gene mutation
- Description: This glycoprotein E/G/UL23 mutant is from Suid herpesvirus 1 (Weigel et al., 2003).
- Detailed Gene Information: Click Here.
- UL23
gene engineering:
- Type: Gene mutation
- Description: This glycoprotein E/G/UL23 mutant is from Suid herpesvirus 1 (Weigel et al., 2003).
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
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Host Response |
Raccoon Response
- Persistence: A glycoprotein E/G/UL23 is attenuated in raccoons (Weigel et al., 2003).
- Efficacy: A glycoprotein E/G/UL23 mutant provides some protection in raccoons from challenge with wild type Pseudorabies virus (Weigel et al., 2003).
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References |
Weigel et al., 2003: Weigel RM, Hahn EC, Scherba G. Survival and immunization of raccoons after exposure to pseudorabies (Aujeszky's disease) virus gene-deleted vaccines. Veterinary microbiology. 2003; 92(1-2); 19-24. [PubMed: 12488067].
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