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Vaccine Detail

Salmonella Gallinarum nuoG mutant vaccine

Vaccine Information

Vaccine Name: Salmonella Gallinarum nuoG mutant vaccine
Target Pathogen: Salmonella spp.
Target Disease: Salmonellosis
Vaccine Ontology ID: VO_0002901
Type: Live, attenuated vaccine
Status: Research
Host Species as Laboratory Animal Model: Chickens
nuoG gene engineering:
- Type: Gene mutation
- Description: This nuoG mutant is from Salmonella Gallinarum (Zhang-Barber et al., 1998).
- Detailed Gene Information: Click Here.
Immunization Route: Intramuscular injection (i.m.)

Host Response

Chicken Response

Persistence: A nuoG mutant is attenuated in chickens (Zhang-Barber et al., 1998).
Efficacy: A nuoG mutant conferred significant protection in chickens from challenge with wild type S. Gallinarum (Zhang-Barber et al., 1998).

References

Zhang-Barber et al., 1998: Zhang-Barber L, Turner AK, Dougan G, Barrow PA. Protection of chickens against experimental fowl typhoid using a nuoG mutant of Salmonella serotype Gallinarum. Vaccine. 1998; 16(9-10); 899-903. [PubMed: 9682335].