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Vaccine Detail
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Streptococcus equi vicK mutant vaccine |
| Vaccine Information |
- Vaccine Name: Streptococcus equi vicK mutant vaccine
- Target Pathogen: Streptococcus equi
- Target Disease: Strangles (also equine distemper)
- Vaccine Ontology ID: VO_0002798
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse
- vicK
gene engineering:
- Type: Gene mutation
- Description: This vicK mutant is from Streptococcus equi (Liu et al., 2008).
- Detailed Gene Information: Click Here.
- Immunization Route: intranasal immunization
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| Host Response |
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Mouse Response
- Persistence: A vicK mutant is attenuated in mice (Liu et al., 2008).
- Efficacy: A vicK mutant induces protection in mice from challenge with wild type S. equi (Liu et al., 2008).
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| References |
Liu et al., 2008: Liu M, McClure MJ, Zhu H, Xie G, Lei B. The Two-Component Regulatory System VicRK is Important to Virulence of Streptococcus equi Subspecies equi. The open microbiology journal. 2008; 2; 89-93. [PubMed: 19088917].
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