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Vaccine Detail
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Yersinia enterocolitica ompR mutant vaccine |
| Vaccine Information |
- Vaccine Name: Yersinia enterocolitica ompR mutant vaccine
- Target Pathogen: Yersinia enterocolitica
- Target Disease: Yersiniosis
- Vaccine Ontology ID: VO_0002937
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse
- ompR
gene engineering:
- Type: Gene mutation
- Description: This ompR mutant is from Yersinia enterocolitica (Dorrell et al., 1998).
- Detailed Gene Information: Click Here.
- Immunization Route: Oral immunization
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| Host Response |
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Mouse Response
- Persistence: An ompR mutant is attenuated in mice (Dorrell et al., 1998).
- Efficacy: An ompR mutant provided partial protection in mice from challenge with wild type Y. enterocolitica (Dorrell et al., 1998).
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| References |
Dorrell et al., 1998: Dorrell N, Li SR, Everest PH, Dougan G, Wren BW. Construction and characterisation of a Yersinia enterocolitica O:8 ompR mutant. FEMS microbiology letters. 1998; 165(1); 145-151. [PubMed: 9711851].
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