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Vaccine Detail
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Yersinia enterocolitica htrA mutant vaccine |
| Vaccine Information |
- Vaccine Name: Yersinia enterocolitica htrA mutant vaccine
- Target Pathogen: Yersinia enterocolitica
- Target Disease: Yersiniosis
- Vaccine Ontology ID: VO_0002936
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Mouse
- htrA
gene engineering:
- Type: Gene mutation
- Description: This htrA mutant is from Yersinia enterocolitica (Li et al., 1996).
- Detailed Gene Information: Click Here.
- Immunization Route: Oral immunization
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| Host Response |
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Mouse Response
- Persistence: An htrA mutant is attenuated in mice (Li et al., 1996).
- Efficacy: An htrA mutant provides partial protection in mice from challenge with wild type Y. enterocolitica (Li et al., 1996).
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| References |
Li et al., 1996: Li SR, Dorrell N, Everest PH, Dougan G, Wren BW. Construction and characterization of a Yersinia enterocolitica O:8 high-temperature requirement (htrA) isogenic mutant. Infection and immunity. 1996; 64(6); 2088-2094. [PubMed: 8675311].
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