• Vaccine Name: C. muridarum PmpG-1, PmpE/F-2, and MOMP Proteins Vaccine
• Target Pathogen: Chlamydia muridarum
• Vaccine Ontology ID: VO_0004257
• Type: Subunit vaccine
• Status: Research
• Antigen: Chlamydia proteins PmpG-1, PmpE/F-2, and MOMP (Yu et al., 2010).
• Adjuvant:
  • Adjuvant name:
  • VO adjuvant ID: VO_0001334
  • Description: Abisco-100
• Immunization Route: subcutaneous injection

Mouse Response

• Host Strain: C57BL/6 and BALB/c
• Vaccination Protocol: Mice were vaccinated 3 times subcutaneously with PmpG-1 plus PmpE/F-2 plus MOMP plus AbISCO-100 (G+F+M+AbISCO) (Yu et al., 2010).
• Challenge Protocol: Two weeks after the final immunization, the mice in the three animal trials described above were then challenged with live EBs for protection evaluation (Yu et al., 2010).
• Efficacy: The combination of three Chlamydia proteins formulated with AbISCO exhibited significant protection at day 13 compared to the group with adjuvant alone (Yu et al., 2010).