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Vaccine Detail
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Inactivated HIV-2 Vaccine with PMMA |
| Vaccine Information |
- Vaccine Name: Inactivated HIV-2 Vaccine with PMMA
- Target Pathogen: Human Immunodeficiency Virus
- Target Disease: Acquired Immunodeficiency Syndrome (AIDS)
- Vaccine Ontology ID: VO_0004242
- Type: Inactivated or "killed" vaccine
- Status: Research
- Adjuvant:
- Immunization Route: subcutaneous injection
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| Host Response |
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Mouse Response
- Host Strain: NMRI
- Vaccination Protocol: Mice received 0.5 ml of the specified vaccine preparations subcutaneously under the abdominal skin on day 0 (Stieneker et al., 1991).
- Immune Response: Mice immunized with PMMA adjuvant had higher antibody counts than mice immunized with an alum adjuvant (Stieneker et al., 1991).
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| References |
Stieneker et al., 1991: Stieneker F, Kreuter J, Löwer J. High antibody titres in mice with polymethylmethacrylate nanoparticles as adjuvant for HIV vaccines. AIDS (London, England). 1991; 5(4); 431-435. [PubMed: 2059385].
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