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Vaccine Detail
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gp120 recominant with MDP adjuvant |
| Vaccine Information |
- Vaccine Name: gp120 recominant with MDP adjuvant
- Target Pathogen: Human Immunodeficiency Virus
- Target Disease: Acquired Immunodeficiency Syndrome (AIDS)
- Vaccine Ontology ID: VO_0004234
- Type: Subunit vaccine
- Status: Research
- Antigen: Recombinant HIV gp120 derived from CHO cells (Bomford et al., 1992).
- Adjuvant:
- Immunization Route: subcutaneous injection
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| Host Response |
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Mouse Response
- Host Strain: BALB/c
- Vaccination Protocol: Mice were subcutaneously immunized with antigen and adjuvant (Bomford et al., 1992).
- Immune Response: Mice immunized with gp120 adjuvanted with MPD plus pleuronic emulsion resulted in a secondary antibody response (Bomford et al., 1992).
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| References |
Bomford et al., 1992: Bomford R, Stapleton M, Winsor S, McKnight A, Andronova T. The control of the antibody isotype response to recombinant human immunodeficiency virus gp120 antigen by adjuvants. AIDS research and human retroviruses. 1992; 8(10); 1765-1771. [PubMed: 1457190].
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