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Vaccine Detail
V3 VLPs with Gamma inulin adjuvant |
Vaccine Information |
- Vaccine Name: V3 VLPs with Gamma inulin adjuvant
- Target Pathogen: Human Immunodeficiency Virus
- Target Disease: Acquired Immunodeficiency Syndrome (AIDS)
- Vaccine Ontology ID: VO_0004232
- Type: Subunit vaccine
- Status: Research
- Antigen: gp120 V3 loop (Harris et al., 1996).
- Adjuvant:
- Immunization Route: Intramuscular injection (i.m.)
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Host Response |
Mouse Response
- Host Strain: BABL/c
- Vaccination Protocol: Mice were immunized with 10 μg of V3-VLPs without adjuvant in the muscle of the left leg. At the same time, the mice were immunized in the right leg with the other immunogens (Harris et al., 1996).
- Immune Response: Mice immunized with V3 VLPs adjuvanted with gamma inulin showed good CTL responses (Harris et al., 1996).
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References |
Harris et al., 1996: Harris SJ, Woodrow SA, Gearing AJ, Adams SE, Kingsman AJ, Layton GT. The effects of adjuvants on CTL induction by V3:Ty-virus-like particles (V3-VLPs) in mice. Vaccine. 1996; 14(10); 971-976. [PubMed: 8873390].
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