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Vaccine Detail

Brucella Omp19 SodC recombinant vector vaccine
Vaccine Information
  • Vaccine Name: Brucella Omp19 SodC recombinant vector vaccine
  • Target Pathogen: Brucella spp.
  • Target Disease: Brucellosis
  • Vaccine Ontology ID: VO_0009590
  • Type: Recombinant vector vaccine
  • Status: Research
  • Host Species for Licensed Use: Human
  • Host Species as Laboratory Animal Model: Vero cells
  • Antigen: OMP19; SODC
  • Preparation: Recombinant capripoxvirus SPPV (TK-) expressing OMP19 and SODC antigens cultivated in Vero cells using BelloStage‚Ñ¢-3000 bioreactor with BioNOC II® macrocarriers. (Amanova et al, 2025)
  • Description: The study aims to develop a new human brucellosis vaccine using recombinant capripoxvirus vectors expressing Brucella antigens. (Amanova et al, 2025)
Host Response
References
Amanova et al, 2025: Amanova Z, Sametova Z, Chervyakova O, Turyskeldi S, Kurmasheva A, Abitayev R, Ussembay A, Kondibayeva Z, Toktyrova D, Mazbayeva D, Bulatov Y. BelloStageā„¢-3000 Bioreactor Versus Conventional Cultivation of Recombinant Capripoxvirus Expressing Brucella Antigens in Vero Cells: A Step Towards the Development of a New Human Brucellosis Vaccine. Cells. 2025 Oct 20; 14(20); . [PubMed: 41148846].