• Vaccine Name: live attenuated Brucella rough strain vaccine
• Target Pathogen: Brucella spp.
• Target Disease: Brucellosis
• Vaccine Ontology ID: VO_0009381
• Type: Live attenuated vaccine
• Status: Research
• Host Species for Licensed Use: Cattle
• Description: The study aimed to evaluate the safety of the rough strain vaccine against brucellosis in pregnant cattle, addressing the lack of prophylactic strategies for pregnant heifers and cows in many countries. Efficacy: Vaccination with the rough strain had no adverse effect on pregnancy outcomes or calf viability at any gestational period. (Barbosa et al, 2017)

Cattle Response

• Efficacy: Vaccination with the rough strain had no adverse effect on pregnancy outcomes or calf viability at any gestational period. (Barbosa et al, 2017)
• Description: Crossbred cows (N=96) at early, mid, or late pregnancy stages were randomly allocated to vaccine treatment or control groups; outcomes measured included percentage of pregnancies reaching full term, live calves 60 days after delivery, and seropositive calves. (Barbosa et al, 2017)