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Vaccine Detail
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Brucella ovis antigenic complex subunit vaccine |
| Vaccine Information |
- Vaccine Name: Brucella ovis antigenic complex subunit vaccine
- Target Pathogen: Brucella spp.
- Target Disease: Brucellosis
- Vaccine Ontology ID: VO_0009217
- Type: Subunit vaccine
- Status: Research
- Host Species for Licensed Use: Sheep
- Antigen: antigenic complex (HS)
- Preparation: HS was entrapped in conventional and mannosylated poly(anhydride) nanoparticles prepared by solvent displacement method; nanoparticles were gamma-irradiated at 10 kGy or 25 kGy for sterilization suitable for ophthalmic administration. (Da et al, 2009)
- Description: This study developed a novel formulation strategy for delivering the Brucella ovis antigenic extract (HS) into ovine mucosal surfaces. (Da et al, 2009)
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| Host Response |
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| References |
Da et al, 2009: Da Costa Martins R, Gamazo C, Irache JM. Design and influence of gamma-irradiation on the biopharmaceutical properties of nanoparticles containing an antigenic complex from Brucella ovis. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 2009 Jul 12; 37(5); 563-72. [PubMed: 19442721].
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