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Vaccine Detail
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live attenuated Brucella melitensis strain streptomycin non dependent vaccine |
| Vaccine Information |
- Vaccine Name: live attenuated Brucella melitensis strain streptomycin non dependent vaccine
- Target Pathogen: Brucella spp.
- Target Disease: Brucellosis
- Vaccine Ontology ID: VO_0009157
- Type: Live attenuated vaccine
- Status: Research
- Host Species for Licensed Use: Goat
- Host Species as Laboratory Animal Model: rabbits
- Preparation: Both heat-killed and living cells of the strain were used as vaccine formulations. (ELBERG et al, 1958)
- Description: The vaccine strain was isolated and its properties and behavior studied to evaluate its ability to immunize goats against brucella infection and prevent abortion. Efficacy: Demonstrated immunization of goats against brucella infection and protection against abortion; efficacy differed between heat-killed and living cell vaccines. Immune response: Included investigation of cross-immunity between tubercle bacilli and brucellae infections using monocytes from vaccinated and unvaccinated rabbits. (ELBERG et al, 1958)
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| Host Response |
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| References |
ELBERG et al, 1958: ELBERG SS, MEYER KF. Caprine immunization against brucellosis; a summary of experiments on the isolation, properties and behaviour of a vaccine strain. Bulletin of the World Health Organization. 1958; 19(4); 711-24. [PubMed: 13596891].
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