• Vaccine Name: Brucella ovis-vitamin E adjuvant vaccine
• Target Pathogen: Brucella spp.
• Target Disease: Brucellosis
• Vaccine Ontology ID: VO_0009054
• Type: Inactivated vaccine
• Status: Research
• Host Species for Licensed Use: Sheep
• Adjuvant: vitamin E
• Preparation: Water-in-oil emulsion with vitamin E as adjuvant. (Tengerdy et al, 1991)
• Description: Rams vaccinated at 6-8 months of age with a water-in-oil Brucella ovis-vitamin E adjuvant vaccine. Efficacy: Rams vaccinated with the vitamin E adjuvant vaccine had significantly higher serum antibody levels than those vaccinated with commercial B. ovis bacterin or B. melitensis Rev. 1; higher antibody levels persisted two years post-vaccination. Immune response: Elevated and sustained serum antibody levels indicating a strong serological response, likely boosted by natural infection. (Tengerdy et al, 1991)

Sheep Response

• Immune Response: Elevated and sustained serum antibody levels indicating a strong serological response, likely boosted by natural infection. (Tengerdy et al, 1991)
• Efficacy: Rams vaccinated with the vitamin E adjuvant vaccine had significantly higher serum antibody levels than those vaccinated with commercial B. ovis bacterin or B. melitensis Rev. 1; higher antibody levels persisted two years post-vaccination. (Tengerdy et al, 1991)
• Description: Serological antibody level measurement in vaccinated rams compared to commercial B. ovis bacterin and B. melitensis strain Rev. 1 vaccine. (Tengerdy et al, 1991)