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Vaccine Detail
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African Swine Fever Virus 9GL mutant vaccine |
| Vaccine Information |
- Vaccine Ontology ID: VO_0004284
- Type: Live, attenuated vaccine
- Status: Research
- Host Species as Laboratory Animal Model: Swine
- 9GL
gene engineering:
- Type: Gene mutation
- Description: This 9GL mutant is from African Swine Fever Virus Mal (Lewis et al., 2000).
- Detailed Gene Information: Click Here.
- Immunization Route: Intramuscular injection (i.m.)
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| Host Response |
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Pig Response
- Persistence: A 9GL mutant is attenuated in swine (Lewis et al., 2000).
- Efficacy: A 9GL mutant induces significant protection in swine from challenge with wild type ASFV (Lewis et al., 2000).
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| References |
Lewis et al., 2000: Lewis T, Zsak L, Burrage TG, Lu Z, Kutish GF, Neilan JG, Rock DL. An African swine fever virus ERV1-ALR homologue, 9GL, affects virion maturation and viral growth in macrophages and viral virulence in swine. Journal of virology. 2000; 74(3); 1275-1285. [PubMed: 10627538].
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