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Murine leukemia virus

Table of Contents
  1. General Information
    1. NCBI Taxonomy ID
    2. Introduction
  2. Vaccine Related Pathogen Genes
    1. Complete genome (Other)
  3. Vaccine Information
  4. References
I. General Information
1. NCBI Taxonomy ID:
11786
2. Introduction
The murine leukemia virus (MuLV) is one of the simplest retroviruses. The virus uses the mouse as a host and is able to cause cancer in the host. The retrovirus MuLV has a positive, single-stranded sense RNA that replicates via reverse transcription. The virus has been of interest since its discovery the beginning of 1950’s. The virus was considered significant since it was shown to induce leukemia in inoculate mice. While it hasn’t been shown to be effective at infecting humans, it has still proven to be relevant in the study of viral infection in humans through the observation of its behavior in mice models. As a retrovirus, it has also been targeted for possible use as a viral vector (MicrobeWiki - Murine Leukemia Virus).
1. Complete genome
  • Gene Name : Complete genome
  • Sequence Strain (Species/Organism) : Murine leukemia virus
  • NCBI Nucleotide GI : 378404894
  • NCBI Protein GI : 53749063
  • Protein Accession : BAD52415.1
  • Taxonomy ID : 11786
  • Gene Strand (Orientation) : ?
  • Protein Name : GAG polyprotein precursor
  • Protein Note : Graffi GV-1.4
  • DNA Sequence : Show Sequence 
    >gi|378404894|dbj|AB187566.2| Murine leukemia virus Graffi GV-1.4 DNA, complete genome
GCGCCAGTCCTCCGATAGACTGTGTCGCCCGGGTACCCGTTCCTAATAAAGCCTCTTGCTGTTTGCATCC
GAATCGTGGTCTCGCTGGTCCTTGAGAGGGTCTCCTCAGATTGATTGACTGCCCACCTCGGGGGTCTTTC
ATTTGGGGGCTCGTCCGGGATCCGGAGACCCCAGCCCAGGGACCACCGACCCACCACCGGGAGGTAAGCT
GGCCAGCAACTGATCTGTGTCTGTCCGATTGTCCTGTATCTGTGACTGATTTTATGCGCCTGCGTCTGTA
CTAGTTGGCCGACTAGCTCTGTACCTGGCGGACCCGTGGTGGAACTGACGAGTTCGGAACACCCGGCCGC
AACCCTGGGAGACGTCCCGGGGACTCCAGGGGCCGTTTTCGTGGCCCGGCCTGAGTCCAAAAGCCCTGAT
CGCTTTGGACTTTTTGGCGCACCCCCCTTAGAAGAGGGGTACGTGGTCCTAGTAGGGGACGAGAGGCTGA
AACAGTTTCCGCCTCCGTCTAAATTTTTGCTTTCGGTTTGGAGCCGAAGCCGCGCCGCGCGTCTCGTCTG
CTGCAGCATCGTTCTGTGTTGTTTCTGTCTGAGCGTGTTTTTGTATTTGTCTGAAAATATGGGCCAGACT
GTTGTCACTCCCTTAAGTCTGACCCTAGATCACTGGAAGGATGTCGAGCGGATCGCTCACAACCAGTCGG
TAGATATCAAGAAAAGGCGGTGGGTCACCTTCTGCTCTGCAGAATGGCCGACCTTTAACGTCGGATGGCC
GCAGGACGGCACTTTCGACCGAGGCATTATCACCCAAGTTAAGATCAAGGTCTTTTCACCTGGTCCGCAT
GGGCACCCGGACCAGGTCCCCTATATTGTGACCTGGGAAGCCTTGGCATTTGACCCCCCCCCTTGGGTCA
AGCCCTTCGTACCTTCTAAACCTCCTCTTCCCCCTTCCGCCCCGTCCCTCTCTCCTGAACCTCCGCTTTC
GACCCCGCCTCGATCTTCCCTCTATCCGGCCCTTACTCCACCTGTAAGCACCAAACCTAAAGTTCTTTCT
GACAGTGGGGGGCCGCTCGTCGACCTGCTTGCAGAAGACCCCCCACCTTACAGAGGCCCAGGGTCACCCC
CTCCCGACGGAGACGGGGATGGCGGGGAAGCGGCCCCTGCCGAAGAGACACCTGACCCCTCCCCAATGGC
GTCTCGCCTGCGAGGAAGACGAGAGCCCCCCGTGGCAGACTCCACCACCTCGCAGGCACTCCCCCTCCGT
TTAGGGGGAAACGGGCAGCTCCAGTACTGGCCGTTCTCCTCCTCTGACCTGTATAATTGGAAAAATAACA
ACCCTTCTTTTTCTGAGGATCCAGGTAAATTGACTGCTCTAATTGAGTCAGTCCTTATTACTCACCAGCC
CACCTGGGATGACTGCCAGCAGCTATTAGGGACCCTGTTGACCAGTGAAGAAAAACAACGGGTACTCTTG
GAAGCTAGGAAAGCCGTCAAGGGCGACGATGGGCGCCCTACCCAGTTACCCAACGAGGTCAACGCAGCTT
TTCCCCTTGAGCGTCCCAACTGGGATCATACCACCCAAGAAGGTAGGAACAACCTAGTCCTCTATCGCCA
GTTGCTCCTAGCGGGTCTCCAAAACGCGGGCAGAAGCCCCACCAATTTGGCCAAGGTAAAAGGGATAACA
CAGGGGCCCAATGAGTCTCCCTCAGCTTTTCTAGAGAGGCTTAAGGAAGCCTATCGTAGGTACACCCCCT
ACGATCCTGAAGACCCTGGACAAGAGACTAACGTGGCTATGTCTTTCATTTGGCAGTCTGCCCCAGATAT
TGGGAGAAAGTTAGAGAGATTAGAAGACTTAAGGAGTAAAACGCTTGGAGACCTAGTGAGAGAGGCAGAA
AAGATATTCAATAAAAGAGAGACACCTGAAGAAAGGGAGGAACGGATCCGAAGGGAGACTGAAGAGAAAG
AAGAACGCTGGAGAGCTGAAGATGAACAGAGAGAAAAGGAAAGAGATCGTAGGAGACATAGAGAAATGAG
CAAGCTATTGGCTACTGTCGTTAGTGGTCAGAAACAGGATAGACAGGTGGGAGAGCGAAGGAGGCCCCAA
CTCGATCATGACCAGTGTGCCTACTGTAAAGAAAAGGGGCACTGGGCTAAGGATTGTCCCAAGAAACCAC
GAGGGCCTCGAGGACCGAGACCCCAGACCTCCCTCCTGACCCTAGATGACTAGGGAGGTCAGGGTCAGGA
CCCCCCCCCTGAACCCAGGATAACCCTCAAAGTTGGGGGGCAACCCGTCACCTTCCTGGTAGATACTGGG
GCCCAACACTCCGTGCTGACCCAAAATCCTGGACCCCTAAGTGACAAGTCTGCCTGGGTCCAAGGGGCTA
CTGGAGGAAAGCGGTATCGCTGGACCACGGATCGCAAAGTACATCTAGCTACCGGTAAGGTCACCCACTC
TTTCCTCCATGTACCAGACTGCCCCTATCCTCTGTTAGGAAGAGACTTGCTGACTAAACTAAAAGCCCAG
ATCCACTTCGAGGGATCAGGAGCTCAGGTTGTGGGACCAATGGGACAGCCCCTGCAAGTGCTGACCCTAA
ACATAGAAGATGAGTATCGGCTACATGAGACCTCAAAAGAGCCGGATGCTTCTCTAGAGTCCACATGGCT
TTCTGATTTTCCCCAGGCCTGGGCGGAAACCGGGGGCATGGGACTGGCAGTTCGCCAAGCGCCTCTGATT
ATACCTCTAAAAGCAACCTCCACCCCTGTGTCCATAAAACAATACCCCATGTCGCAAGAAGCCAGACTGG
GGATCAAGCCCCACATACAGAGGCTGTTGGACCAGGGAATATTGGTACCCTGCCAGTCCCCCTGGAATAC
ACCCCTGCTACCCGTTAAGAAACCAGGGACTAATGATTATAGGCCTGTCCAAGATTTGAGAGAAGTCAAC
AAGCGGGTGGAAGATATCCACCCCACCGTGCCCAACCCTTACAACCTCCTGAGCGGGCTCCCACCGTCTC
ACCAGTGGTACACTGTACTTGACTTGAAAGATGCTTTTTTCTGCTTAAGACTCCACCCCACTAGCCAGCC
TCTCTTCGCCTTTGAGTGGAGAGACCCAGAGATGGGAATCTCGGGACAGTTGACCTGGACCAGACTTCCA
CAAGGCTTCAAGAACAGCCCCACTCTGTTCGACGAGGCATTGCATAGAGACCTAGCAGGCTTCCGGATCC
AGCATCCAGACTTGATCCTGCTGCAATACGTGGATGACTTACTGCTAGCCGCCACTTCCGAAAACGACTG
CCAACAAGGTACTCGGGCCCTGTTACAGATCTTAGGGGACCTCGGGTATCGGGCCTCGGCCAAGAAAGCC
CAAATCTGCCAGAAACAGGTCAAGTATCTGGGGTATCTTCTAAAAGAGGGTCAGAGATGGCTGACTGAGG
CCAGAAAGGAGACTGTGATGGGGCAGCCTATTCCGAAGACCCCTCGACAACTAAGGGAGTTCCTAGGGAC
GGCAGGCTTCTGTCGCCTCTGGATCCCGGGGTTTGCAGAAATGGCAGCCCCCTTGTACCCTCTCACCAAA
ACGGGGACTCTGTTTAATTGGGGCCCAGACCAGCAAAAGGCCTATCAAGAAATCAAACAGGCTCTTCTAA
CGGCCCCAGCCTTGGGGTTACCAGACTTGACTAAGCCCTTTGAACTCTTTGTTGACGAGAAGCAGGGCTA
CGCCAAAGGCGTCCTAACGCAGAGACTGGGACCCTGGCGTCGGCCGGTGGCCTACCTGTCCAAAAAGCTC
GACCCCGTGGCCGCGGGATGGCCCCCTTGCTTGCGGATGGTGGCTGCCATTGCCGTTCTGACAAAAGATG
CAGGCAAGCTCACCCTGGGACAGCCGCTAGTCGTTCTAGCCCCCCATGCGGTGGAGGCGCTAGTCAAACA
ACCCCCTGACCGCTGGCTCTCCAACGCCCGGATGACTCACTATCAGGCTTTGCTTCTGGACACGGACCGG
GTCCAGTTCGGACCGGTGGTGGCCCTGAACCCGGCTACGCTGCTTCCACTGCCTGAGGAAGGGCTACGAC
ATGACTGCCTTGATATTCTGGCCGAAGCCCACGGAACTAGACCGGACTTAACGGACCAGCCACTCCCCGA
CGCCGACCACACCTGGTACACGGATGGGAGCAGTTTCCTGCAAAAAGGGCAGCGTAAGGCCGGAGCAGCG
GTAACCACCGAGACCGAGGTAATCTGGGCCAAGGCGTTGCCATCCGGGACATCGGCCCAGAGAGCTGAAC
TAATAGCACTCACCCAAGCCCTAAAGATGGCAGAAGGTAAGAAGCTAAATGTTTATACTGATAGCCGCTA
TGCCTTTGCTACTGCCCATATTCATGGAGAGATATATAGGAGGCGTGGATTGCTCACATCAGAGGGGAAA
GAGATCAAAAACAAAGGTGAAATCTTGGCCCTATTAAAAGCCCTCTTTCTGCCTAAAAGACTTAGCATAA
TCCATTGCCCAGGACACCAAAAAGGAAACAGCGCGGAGGCCAGAGGCAACCGAATGGCTGACCAAGCGGC
CCGAGAAATAGCCTCTAAAGAAACCCCAGAGACTTCCACACTGCTTATAGAAAATTCAACACCCTATACC
CATGAACATTTTCATTACACAGTGACTGACATAAAGGACCTAACTAAGTTGGGAGCCACTTATGATAAAA
CAAAGAAGTACTGGGTCTACCAAGGGAAACCTGTGATGCCCGACCAATTTACCTTTGAATTATTAGATTT
TCTCCATCAGTTGACCCACCTCAGTTTCTCAAAGACAAAGGCTCTCCTAGAGAGAAGCCACAGTCCCTAC
TACATGCTGAACCGGGATCGAACACTGAAAAATATCATTGAGACCTGCCAAGCTTGTGCGCAAGTCAATG
CCAGCAAGTCAGCCGTTACCCAAGGAACTAGGGTCCGCGGACATCGGCCCGGTACTCACTGGGAGATCGA
TTTTACCGAGGTAAAGCCTGGACTGTATGGGTATAAATATCTTCTAGTTTTTGTAGACACCTTCTCTGGC
TGGGTTGAAGCCTCCCCTACTAAGAAAGAAACCGCCAAGGTCGTAACCAAGAAACTACTAGAAGAGATCT
TCCCCAGGTTCGGCATGCCACAGGTATTGGGAACAGACAATGGGCCTGCCTTCGTCTCCAAGGTGAGTCA
GACAGTAGCCGATTTAATGGGGATTGATTGGAAACTACATTGTGCATACAGACCCCAAAGCTCAGGTCAG
GTAGAAAGAATGAATAGGACCATCAAGGAGACTTTAACTAAATTAACGCTTGCAACTGGCTCTAGAGACT
GGGTGCTTCTACTCCCCCTAGCCCTGTATCGAGCCCGCAACACGCCGGGCCCCCATGGCCTCACCCCGTA
CGAGATCTTATATGGAGCACCTCCGCCCCTTGTAAACTTCCCTGATCCTGACATGACGAGAGTCACTAAC
AGCCCCTCTCTCCAAGCTCACTTGCAGGCCCTCTACTTAGTCCAGCACGAAGTCTGGAGACCGCTGGCTG
CAGCCTACCAGGAACAACTGGACCGGCCGGTGGTACCCCACCCTTACCAGGTCGGCGACACAGTGTGGGT
CCGCCGACACCAGACTAAGAACCTTGAACCTCGCTGGAAGGGACCTTACACCGTCCTGCTGACCACCCCC
ACCGCCCTCAAAGTAGACGGCATCGCAGCCTGGGTCCACGCCGCCCACGTGAAGGCAGCCAATACTGGGA
GTGGACCATCCTCTGGACTGACATGGCGCGTGCAACGCTCTCAAAACCCCTTAAAAATAAGGCTAACCCG
CAAGGCCCCCTAGTCCCCCTAATCCTTTTGATTCTCAGAGGAGTCAGTACCGCCTCGCCTGGCTCCAGCC
CTCACCGGGTCTATAACATCACCTGGGAGATAACCAATGGAGATCGGGAGGTGGTATGGGCAATATCTGG
CAACCACCCCCTGTGGACCTGGTGGCCTGACCTCACCCCAGATTTATGCATGTTGGCCCACCATGGACCA
TCTTATTGGGGCCTAGAGTATCAGTCCCCTTTCTCCTCTCCCCCGGGGCCCCCTTGTTGCTCAGAGAGCA
GCAAGTCTAGCCGGGGCTGTTCCAGAGACTGTGAAGAACCCTTAACCTCCCTCACTCCCCGGTGCAGCAC
TGCCTGGAACAGGCTGAAACTGGACAAGGTAACCCATGCACCCAATGAGGGATTCTATATCTGCCCGGGG
TTTCATCGCCCCCGGTGGTCCAAGTCATGTGGGGGCCCAGACTCCTTTTACTGTGCCTCATGGGGTTGTG
AGACCACCGGACGGGCATATTGGAAACCCTCCTCTTCCTGGGATTACATCACAGTAGACAACAACCTCAC
CTCCAGTCAAGCTGCCCCAATATGTAAAGCCAATAAATGGTGTAACCCCTTAGTTATCCGGTTTACGGAT
GCCGGAAAACGTGTTACCTCTTGGGTCACAGGACATCACTGGGGCCTACGCTTGTATGTCTCCGGACAAG
ACCCAGGGCTCAATTTTGGAATCCGATTCAAATACCAAAGTTTGGGACCCCGAGTTCCCATAGGGCCAAA
CCCCGTCCTGGCGGTTCCACAACCACCCTTGGTGTCAGAAGTTAAGACCCCCTCAGCCACCAACTCCACC
AGCTCGCCAGGTGAGACTCCTCTCTCTCTCACCCAACTTCCACCAGTGGGAACGGGAAATAGGTTACTAA
ACTTGGTAGATGGAGCCTACCAAGCTCTCAACCTCACCAGTCCTGACAGAACTCAAGAGTGCTGGTTGTG
TCTGGTGACGGAACCCCCCTACTACGAAGGAGTTGCCGTTCTAGGGACTTATTCTAACCATACCTCTGCT
CCAGCTAACTGCTCCGTGGCCTCCCAACACAAGCTGACCCTGTCCGAAATAACCGGACAGGGACTCTGCG
TAGGAGCAATTCCCAAAACCCATCAGGCCCTATGCAATGTCACCCAGACAAACAGCCCAGGGACCCATTA
TTTAGTTGCCCCTGCAGGTACCATGTGGGCATGTAATACAGGGCTTACCCCATGTCTCTCCACCGCTGTA
CTTGATCTTACCACTGATTATTGTGTTCTTGTTGAACTCTGGCCAAGGGTCACCTATCATTCCCCCAGCT
ATGTTTACAGCCAGTTCGAAAGATCCATCCGACACAAAAGAGAACCGGTGTCGTTAACATTGGCCCTATT
GTTGGGTGGACTAACCATGGGGGGAATTGCCGCAGGGATAGGAACAGGAACTACTGCTCTGATGGCCTCT
CAGCAGTTCCAGCAGCTCCATGCTGCTGTACAGGATGACCTTAAAGAAATTGAAAAGTCAATCTCTAACC
TAGAAAAATCTCTTACTTCACTGTCTGAAGTTGTCTTACAGAATCGAAGAGGCCTAGACTTGTTATTCCT
AAAAGAAGGAGGGCTGTGTGCTGCTTTAAAAGAAGAATGTTGTTTCTATGCAGACCACACAGGACTAGTA
AGGGACAGCATGGCCAAGTTGAGAGAGAGGCTCAACCAGAGACAAAAACTGTTTGAGTCAGGTCAGGGAT
GGTTTGAGGGACTGTTTAACAGGTCCCCATGGTTCACGACTTTGATATCCACCATTATGGGCCCCTTGAT
AATACTTTTATTAATCCTACTCCTCGGACCCTGTATTCTCAACCGCTTGGTCCAGTTTGTAAAAGACAGA
ATTTCGGTGGTGCAGGCCCTGGTTCTGACCCAACAGTATCACCAACTCAAATCAATAGATCCAGAAGAAG
TGGAGTCACGTGAATAAAAGATTTTATTCAGTTTCCAGAAAGAGGGGGGAATGAAAGACCCCACCATAAG
GCTTAGCAAGCTAGCTACAGTAACGCCATCTTGCAAGGCCTGGAAAAATACAGGACTGAGAATAGGGAAG
TTCAGATCAAGGTCAGAGCAGAAAAACAGCTGCAGTTGGGCCAAACAGGATATCTGTGGTGAGCAGTTTC
GGGCCCCGGCCCGGGGGCAAGAACAGATGGTCCCCAGATATGGCCTAACCCTCAGCAGTTTCAAGAGACC
CATCAGATGTTTCCAGGTTGCCCCAAAGACCTGAAACGACCTTGCGCCTCATTTGAACTAACCAATCAGC
CCGCTTCTCGCTTCTGTTCGCGCGCTTCTGCTCCCCGAGCTCTATAAAAGAGGCCCAAGAACCCTTACTC
GGCGCGCCAGTCCTCCGATAGACTGTGTCGCCCGGGTACCCGTTCCTAATAAAGCCTCTTGCTGTTTGCA
  • Molecule Role : Other
III. Vaccine Information
IV. References
1. MicrobeWiki - Murine Leukemia Virus: Murine Leukemia Virus (MuLV) [http://microbewiki.kenyon.edu/index.php/Murine_Leukemia_Virus_(MuLV)]