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Pathogen Page
Haemophilus parasuis

Table of Contents

  1. General Information
    1. NCBI Taxonomy ID
    2. Disease
    3. Introduction
    4. Microbial Pathogenesis
    5. Host Ranges and Animal Models
    6. Host Protective Immunity
  2. Vaccine Related Pathogen Genes
    1. csgG (Haemophilus parasuis SH0165)
    2. FOG (Haemophilus parasuis SH0165)
    3. gapA (Haemophilus parasuis SH0165)
    4. gcp (Haemophilus parasuis)
    5. hsdS (Haemophilus parasuis)
    6. hxuB (Haemophilus parasuis)
    7. hxuC (Haemophilus parasuis)
    8. LppC (Haemophilus parasuis)
    9. ndk (Haemophilus parasuis)
    10. omp26 (Haemophilus parasuis)
    11. oppA (Haemophilus parasuis)
    12. outer membrane protein A (Haemophilus parasuis)
    13. outer membrane protein D15 (Haemophilus parasuis str. Nagasaki])
    14. outer membrane protein P2 (Haemophilus parasuis str. Nagasaki])
    15. palA (Haemophilus parasuis SH0165)
    16. pflA (Haemophilus parasuis)
    17. plpA (Haemophilus parasuis SH0165)
    18. rnfC (Haemophilus parasuis)
    19. superoxide dismutase (Haemophilus parasuis)
    20. tbpA (Haemophilus parasuis)
    21. tbpB (Haemophilus parasuis)
    22. TolC (Haemophilus parasuis)
    23. VtaA5 (Haemophilus parasuis str. Nagasaki)
    24. VtaA6 (Haemophilus parasuis str. Nagasaki)
    25. VtaA8 (Haemophilus parasuis str. Nagasaki)
    26. VtaA9 (Haemophilus parasuis str. Nagasaki)
    27. yfeA (Haemophilus parasuis SH0165)
    28. ygiW (Haemophilus parasuis D75)
  3. Vaccine Information
    1. Haemophilus Parasuis Avirulent Live Culture Vaccine (USDA: 19J1.00)
    2. pCgap DNA vaccine encoding glyceraldehyde-3-phosphate dehydrogenase
    3. Porcine Reproductive & Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine-Erysipelothrix Rhusiopathiae-Haemophilus Parasuis Bacterin (USDA: 49V9.20)
    4. Porcine Reproductive & Respiratory Syndrome Respiratory Form, Modified Live Virus Vaccine-Haemophilus Parasuis Bacterin (USDA: 49Q9.20)
  4. References
I. General Information
1. NCBI Taxonomy ID:
738
2. Disease:
Glasser's disease
3. Introduction
H. parasuis is a non-motile, small, pleomorphic rod in the family Pasteurellaceae, and is the etiologic agent of Glasser's disease. Glasser’s disease is characterized by fibrinous polyserositis, polyarthritis and meningitis. H. parasuis often produces acute septicemia, and its endotoxin induces disseminated intravascular coagulation, resulting in the formation of microthrombi in several organs (Oliveira and Pijoan, 2004).
4. Microbial Pathogenesis
H. parasuis colonizes the respiratory tracts of pigs, and can then cause systemic infection (Oliveira and Pijoan, 2004).
5. Host Ranges and Animal Models
Pigs
6. Host Protective Immunity
Early colonized pigs are protected against systemic infection by maternal antibodies. As maternal immunity decreases, these pigs are able to mount an active immune response to these virulent strains (Oliveira and Pijoan, 2004).
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