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Pathogen Page

Avian Encephalomyelitis Virus

Table of Contents

General Information
Vaccine Information
References

I. General Information

1. NCBI Taxonomy ID:

70796

2. Disease:

Avian Encephalomyelitis

3. Introduction

Avian encephalomyelitis (AE) is a disease of young chickens, pheasants, quail and turkeys, observed worldwide. Infection of poultry with AE virus (AEV) by the faecal-oral route is common, field strains being enterotropic. The virus can cause slight reduction in egg production in susceptible laying hens and can be transmitted in embryos (Marvil et al., 1999).

4. Host Ranges and Animal Models

Chickens, pheasants, coturnix quail and turkeys have all been susceptible to natural infection with the avian encephalomyelitis virus. Experimentally, ducklings, poults, young pigeons, and guinea fowl have been infected with AEV (Calneck, B. W., 2003).

5. Host Protective Immunity

Birds that have recovered from infection develop antibodies that can neutralize the virus (Calneck, B. W., 2003).

II. Vaccine Information

1. AE-Poxine

a. Product Name:

Avian Encephalomyelitis - Fowl Pox Vaccine, Live Virus

b. Tradename:

AE-Poxine

c. Manufacturer:

Zoetis

d. Vaccine Ontology ID:

VO_0004603

e. Type:

Live, attenuated vaccine

f. Status:

Licensed

g. Host Species for Licensed Use:

Chicken

h. Immunization Route

Intradermal injection (i.d.)

i. Storage

Store at not over 45°F (7°C) (AE-Poxine).

2. Avian Encephalomyelitis Killed Virus Vaccine (USDA: 1015.I0)

a. Manufacturer:

SolidTech Animal Health, Inc.

b. Type:

Inactivated or "killed" vaccine

c. Status:

Licensed

d. Location Licensed:

USA

e. Host Species for Licensed Use:

Chicken

3. Avian Encephalomyelitis Live Virus Vaccine (USDA: 1051.10)

a. Manufacturer:

Intervet Inc., Biomune Company

b. Type:

Live vaccine

c. Status:

Licensed

d. Location Licensed:

USA

e. Host Species for Licensed Use:

Chicken

4. Avian Encephalomyelitis Live Virus Vaccine (USDA: 1051.11)

a. Manufacturer:

Wyeth, Intervet Inc., Lohmann Animal Health International, Merial, Inc.

b. Type:

Live vaccine

c. Status:

Licensed

d. Location Licensed:

USA

e. Host Species for Licensed Use:

Chicken

5. Avian Encephalomyelitis Live Virus Vaccine (USDA: 1051.12)

a. Manufacturer:

Intervet Inc.

b. Type:

Live vaccine

c. Status:

Licensed

d. Location Licensed:

USA

e. Host Species for Licensed Use:

Chicken

6. Avian Encephalomyelitis-Chicken Anemia Virus-Fowl Pox Live & Modified Live Virus Vaccine (USDA: 10T1.40)

a. Manufacturer:

Intervet Inc.

b. Vaccine Ontology ID:

VO_0002039

c. Type:

Live vaccine

d. Status:

Licensed

e. Location Licensed:

USA

f. Host Species for Licensed Use:

Chicken

7. Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.10 )

a. Manufacturer:

Wyeth, Lohmann Animal Health International, Merial, Inc.

b. Vaccine Ontology ID:

VO_0002033

c. Type:

Live vaccine

d. Status:

Licensed

e. Location Licensed:

USA

f. Host Species for Licensed Use:

Chicken

8. Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.11)

a. Manufacturer:

Intervet Inc.

b. Vaccine Ontology ID:

VO_0002034

c. Type:

Live vaccine

d. Status:

Licensed

e. Location Licensed:

USA

f. Host Species for Licensed Use:

Chicken

9. Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.13)

a. Manufacturer:

Intervet Inc.

b. Vaccine Ontology ID:

VO_0002035

c. Type:

Live vaccine

d. Status:

Licensed

e. Location Licensed:

USA

f. Host Species for Licensed Use:

Chicken

10. Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.14)

a. Manufacturer:

Intervet Inc.

b. Vaccine Ontology ID:

VO_0002036

c. Type:

Live vaccine

d. Status:

Licensed

e. Location Licensed:

USA

f. Host Species for Licensed Use:

Chicken

11. Avian Encephalomyelitis-Fowl Pox Live Virus Vaccine (USDA: 10M1.40)

a. Manufacturer:

Biomune Company

b. Vaccine Ontology ID:

VO_0002037

c. Type:

Live vaccine

d. Status:

Licensed

e. Location Licensed:

USA

f. Host Species for Licensed Use:

Chicken

12. Avian Encephalomyelitis-Fowl Pox-Laryngotracheitis Live Virus, Live Fowl Pox Vector Vaccine (USDA: 10S1.R0)

a. Manufacturer:

Biomune Company

b. Vaccine Ontology ID:

VO_0002038

c. Type:

Live vaccine

d. Status:

Licensed

e. Location Licensed:

USA

f. Host Species for Licensed Use:

Chicken

13. Avian Encephalomyelitis-Fowl Pox-Mycoplasma Gallisepticum Live Fowl Pox Vector, Live Virus Vaccine (USDA: )

a. Manufacturer:

Biomune Company

b. Type:

Live vaccine

c. Status:

Licensed

d. Location Licensed:

USA

e. Host Species for Licensed Use:

Chicken

III. References

1. AE-Poxine: AE-Poxine vaccine website [https://online.zoetis.com/US/EN/Products/Pages/AE_Poxine.aspx]

2. Calneck, B. W., 2003: Bruce N. Calneck. Avian Encephalomyelitis. 271-281. Diseases of poultry, 11th ed. 2003. Iowa State University Press, Ames, IA.

3. Marvil et al., 1999: Marvil P, Knowles NJ, Mockett AP, Britton P, Brown TD, Cavanagh D. Avian encephalomyelitis virus is a picornavirus and is most closely related to hepatitis A virus. The Journal of general virology. 1999; 80 ( Pt 3); 653-662. [PubMed: 10092005].