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OMPDC

Gene Name OMPDC
Sequence Strain (Species/Organism) Toxoplasma gondii ME49
NCBI Gene ID 7899615
NCBI Protein GI 237831731
Locus Tag TGME49_059690
Genbank Accession DS984728
Protein Accession XP_002365163
Taxonomy ID 508771
Gene Starting Position 2298541
Gene Ending Position 2301456
Gene Strand (Orientation) +
Protein pI 4.79
Protein Weight 31611.79
Protein Length 320
DNA Sequence
>gi|212659390:2298541-2301456 Toxoplasma gondii ME49 scf_1112359874900, whole genome shotgun sequence
GATGCCGGCAGACGCGCTGCGTGAGAAGCCGGTTGTCCAGGCTGCTGTGAATACCTCGGAAGGGTGCAAG
AACTTCTTCAAGACATTGGATGCAAGGATCGAAGCGGTAGATTCCTTGCTCACAGTCGGCCTTGATCCGC
ACATCGCGGACCTCCCGTCGCCAGCCACAGCTGAGCGTGCCTTTGTATTTTGTGAACGCATCATCAGGGA
AACTCTTCCTTTTACGTGTTGTTACAAACCGAACAGCGCGTTTTTTGAGGCATTTGGTCCCCCGGGTTTG
CAGGTACGTATTTCAATGTGAGGATGGAGCATGGTTGTCATGGCCAGATATACTTTAGCCCGACAACGTT
ACCAGGCATTTGGAGTACCTCCAACTCCTCAGTTGCAAAGATACACTGCACATGCTCGTGTAGTACCGCT
GAGAGACAGAACCACTTGAAACGTCATCTTTCATTAGTATGAAGCGGTTGTCCGAAGTTCGGCCATCATT
CTGGAATCTATCAGTCCTATGTTTCCTCACTGCCTAGGTACTGTTTTCCTGTTTGTGTATATCCCGAAAA
ACTGTATTGAAAGCAAGCAGTGGGGATAGCGGTGAAGCAGGGGGTTGGTGAAGCGGTTTCGGAGGGGACA
GGGAAATACCTTCAATTTTTGAAAGGCGCAGTTCCCTGTTCCTTCGCAGTCACCACGGACAGACTAGAGA
TATGTCTGTTCTGTACGCGCCTTACCAAGACCCGAACCGCGTACAGGGTGCAAACCTTTCGCGCCATAAT
CGAATGCCGCTTGTCGCCACGTGTAGGCACTCGAGAGAGTCTGCGCGCTGATTCCCGACGATGTTCCTAT
TCTTCTAGACGCCAAAAGAGGGGACATAGGATCGACGGCGCAAGCCTACGCATCTTCGGCTTTTGACGCG
TTCAAGGTATGGAACTTCGAGCCCTAAGAGGTTGAAGAGAGTACGTAGAACCATGTTTATTTCATTAACA
TCGAGTCGGTTCTGTATACATACGCGTGCTGCTGCAGTGAATGTATTACAAGATATCTCGTATGCATGCG
CCCGACGAGAATATCGCCAATATCATAGCCTTATGACGTGCGCGATTCGTCTGGTGGCAAATCTGCGGTC
TACAAGTGATCTATTGTCAGCGCATGGCAGTAACGATCTCATCCATTTATGCGGGTGACGCATTACATCG
TGTCTTTTGTCAAAAATGTGCTGCTTGATGTCGCGCAGGCGGACGGTGTCACCGTCAACGCCTACATGGG
CAGAGAAGCAGTTCGACCGTTTCTGTCGTATCGAAACAAAGGCGTATTTGTACTTGTGAAGACGTCGAAT
CAATCGTCCAACGAGTTTCAGACCCTGCCAGTGAGGGTGGAGTCAAGCTCCGACACTCAGGATGTCCCGC
TGTATGTACAGATGGCCAGAGTTTGCAACGAACTTGCCCAAGGTGAGAGTGGGTCCGTCAGCTTCGTTAG
ACCAGCTTCTCTTCCGTTGTATTTGTCTTTTGTGAGCGACCCGTGTCGCCAGAGCTTCATGCTTAGCTAC
ACCGCTCGGCAGAACTGGCATCTCTCTCGCTCCAGGAGTGTGATCCGCGTTTCCAGTTTTTGGTTGATAA
GTCGCACCCCAGAGGAGAAAAATCCTCAGCACCTGCCATACAGATTCAACGGAGTCTCAGGCAGCTTTTT
ACTCCGAGCCCGCACTTGCCCGACCTGCCATTTTCGTTTACACAGAGCCACTTTCTGCGGGGCGGTGGCG
ACAAAAACCGCGAGCTTTGTAGTAAATGAAACCACGTCGTGAGAAGTAGTCCAGTTCTCCCTTCGAACAC
TACGTTGCCTGCTACATATCTGTGCCTCATCGTCGAGTGCCGCTGTCCGTGTCTTGCTCCACTTTGTCAA
TCCGAACTCAGAATGCGTTTCTGAGGAAGACTCTCCATCCACGACTGGACATGGCCTCCGTCATAATGCG
TCGGGCGGTGGTGTCGGACTCGTAGTAGGAGCAACAGATATAGAAGCTCTTCGCGAGGTGCGAAAGGCAT
GCCCGGACCTTTATATTCTTGCTCCCGGAGTCGGTGCCCAAGGAGCGGACCTCGAGAGGGCCTTGAGTGC
CGGTAAGCATGGAGCTGGGTCTCAGTTGAGAGCGAAGTTACACAATTGAATCTGACATTGAGGTTGATTT
GATTGTCGCTTGAGGCGCCTGTGACCCTAATGATCCCGAAACGCAGGAACCATAGAAGCAACGGAGGGAG
ACGGAACCTTGCTGTTTTAGGTCATTGTGCGCTAAACGTGGTTTCTGGTACACCGTGCAAGATCGTATAC
TCACGGGTATGATCGCAGTGAAAATGCTCCTAAGAGCGAAGAAATAAGGTACCACATTTTCAACACCTCT
ACGGTTTTTCCTGTTACTTGGGACTCGTTGCTCTGCCAGGTCTCTGCAAGGACGGCAAAGGGATGCTTAT
TCCCGTCTCTCGTGGCATATCACGAGCGGAGGTAAGGGCAGGTTGTCTTGACACTTGTAGCCCGTAGTTT
TTGAAAATCCAGCACACCGCATAGAACCTTGGTGACAGAGATGCGTGCGTCACTCGAACGAATATTCCGA
TGACGGCGAAGTTGACTGAAGTATTTCTGTTTTCAGCAGTATATTTTTCAGCGTTTGTATGGCCCCAGGA
TGGATGCAAAACCAACCGACTGCGCCCTTCGCTCAGATGTGCGGAATCCACCGGATCCATGCAATAGAAA
ATAGATTTCAGATGACACGGATTTGAGATGAAATCACCCGTTCATAGTACAGCTGTTTGCGTCCACTTTG
TCCGTCCTCCCTGTTCCGTTCCCTTCATTGCAGAATTTAGCTGCCCAAGCTAACGCATACAGAGAACAGA
TCAATGAAGTCAGAAGAGGCATTGTCCAGCAGTACGAGGAAAGCTG
Protein Sequence
>gi|237831731|ref|XP_002365163.1| orotidine-monophosphate-decarboxylase, putative [Toxoplasma gondii ME49]
MPADALREKPVVQAAVNTSEGCKNFFKTLDARIEAVDSLLTVGLDPHIADLPSPATAERAFVFCERIIRE
TLPFTCCYKPNSAFFEAFGPPGLQALERVCALIPDDVPILLDAKRGDIGSTAQAYASSAFDAFKADGVTV
NAYMGREAVRPFLSYRNKGVFVLVKTSNQSSNEFQTLPVRVESSSDTQDVPLYVQMARVCNELAQECVSE
EDSPSTTGHGLRHNASGGGVGLVVGATDIEALREVRKACPDLYILAPGVGAQGADLERALSAGLCKDGKG
MLIPVSRGISRAENLAAQANAYREQINEVRRGIVQQYEES
Molecule Role Virmugen
Molecule Role Annotation An OMPDC mutant, alone or in combination with an UP mutation, is attenuated in mice and induces significant protection from challenge with wild type T. gondii (Fox and Bzik, 2010).
Related Vaccines(s) T. gondii OMPDC mutant vaccine , T. gondii OMPDC/UP mutant vaccine
References