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pfCelTOS

Gene Name pfCelTOS
NCBI Gene ID 811213
NCBI Nucleotide GI AB194052.1
NCBI Protein GI 62954730
Other Database IDs CDD:163532
Taxonomy ID 5833
Gene Strand (Orientation) ?
Protein Name PF cell-traversal protein
Protein pI 4.42
Protein Weight 18979.58
Protein Length 248
Protein Note lysine-2,3-aminomutase; TIGR03820
Protein Sequence
>BAD97684.1 PF cell-traversal protein [Plasmodium falciparum]
MNALRRLPVICSFLVFLVFSNVLCFRGNNGHNSSSSLYNGSQFIEQLNNSFTSAFLESQSMNKIGDDLAE
TISNELVSVLQKNSPTFLESSFDIKSEVKKHAKSMLKELIKVGLPSFENLVAENVKPPKVDPATYGIIVP
VLTSLFNKVETAVGAKVSDEIWNYNSPDVSESEESLSDDFFD

Molecule Role Protective antigen
Molecule Role Annotation Immunization with PfCelTOS resulted in potent humoral and cellular immune responses and most importantly induced sterile protection against a heterologous challenge with P. berghei sporozoites in a proportion of both inbred and outbred mice (Bergmann-Leitner et al., 2010).
Related Vaccines(s) FMP012 with AS01B adjuvant system , P. falciparum pfCelTos protein vaccine
References