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HAP

Gene Name HAP
Sequence Strain (Species/Organism) Streptococcus equi subsp. equi 4047
NCBI Protein GI 4336671
Other Database IDs CDD:226636
CDD:173869
Taxonomy ID 553482
Gene Strand (Orientation) ?
Protein Name hyaluronate-associated protein precursor
Protein pI 5.08
Protein Weight 53754.78
Protein Length 622
Protein Note ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; COG4166
Protein Sequence 
>AAD17886.1 hyaluronate-associated protein precursor [Streptococcus equi subsp. equi 4047]
MTVLGTKACKRLGLAAVTLASVAALMACGNKQSASTDKKSEINWYTPTEIITLDISKNTDTYSALAIGNS
GSNLLRADAKGKLQPDLAEKVDVSEDGLTYTATLRDGLKWSDGSDLTAEDFVYSWQRMVDPKTASEYAYL
ATESHLKNAEDINSGKNPDLDSLGVKADGNKVIFTLTEPAPQFKSLLSFSNFVPQKESFVKDAGKDYGTT
SEKQIYSGPYIVKDWNGTSGTFKLVKNKNYWDAKNVKTETVNVQTVKKPDTAVQMYKQGKLDFANISGTS
AIYNANKKHKDVVPVLEATTAYIVYNQTGAIEGLNSLKIRQALNLATDRKGIVSAAVDTGSKPATALVPT
GLAKLSDGTDLTEHVAPGYKYDDKEAAKLFKEGLAELGKDALTITITADADAPAAKSAVDYIKETWETAL
PGLTVEEKFVPFKQRLEDTKNQNFEVAVVLWGGDYPKGSTFYGLFKSGSAYNYGKFTNADYDAAYNKALT
TDALNTDAAADDYKAAEKALYDNALYNPLYLP
Molecule Role Protective antigen
Molecule Role Annotation Immunization with HAP-GST significantly reduced rhinitis in Balb/C mice challenged nasally with S. equi and significantly increased survival time and clearance of bacteria in CBA/CA mice challenged intraperitoneally with S. zooepidemicus (Chanter et al., 1999).
References