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FlaA from C. jejuni NCTC 11168

Gene Name FlaA from C. jejuni NCTC 11168
Sequence Strain (Species/Organism) Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819
VO ID VO_0010942
NCBI Gene ID 905631
NCBI Protein GI 218562948
Locus Tag Cj1339c
Genbank Accession AL111168
Protein Accession YP_002344727
Other Database IDs BioCyc: CJEJ192222:CJ1339C-MONOMER
EMBL: AL139078
InterPro: IPR001029
InterPro: IPR001492
InterPro: IPR010810
KEGG: cje:Cj1339c
Pfam: PF00669
Pfam: PF00700
Pfam: PF07196
PIR: H81277
PRINTS: PR00207
ProDom: PD000316
UniProt: P56963
Taxonomy ID 192222
Gene Starting Position 1269231
Gene Ending Position 1270949
Gene Strand (Orientation) -
Protein Name flagellin A
Protein pI 5.36
Protein Weight 55763.1
Protein Length 572
Protein Note flaA, flagellin A, len: 572 aa; 80.7% identity to FLAA_CAMJE flagellin A (575 aa), fasta scores; opt: 2816 z-score: 2717.6 E(): 0, 80.7% identity in 575 aa overlap. 48.3% identity to HP0601. Also similar to Cj1338c (flaA), Cj0720c flaC (24.5% identity in 220 aa overlap), and Cj0887c flaD (20.2% identity in 560 aa overlap). Contains fam match to entry PF00669 Flagellin_N, Bacterial flagellin N-terminus, and Pfam match to entry PF00700 Flagellin_C, Bacterial flagellin C-terminus. The flaA and flaB genes have a GC content of 37% compared to the overall genome GC content of 30.5%
Protein Annotation FUNCTION: Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella (UniProt: P56963)

SUBUNIT: Heteropolymer of flaA and flaB (UniProt: P56963)

SIMILARITY: Belongs to the bacterial flagellin family (UniProt: P56963)
DNA Sequence
>NC_002163.1:1269231-1270949 Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819 chromosome, complete genome
ACTACTGTAGTAATCTTAAAACATTTTGTTGAACAGAATTAGCCTGTGCCATGGCATAAGAGCCGCTTTG
AGCTAAGATATTTGCTTTAGAGTAGTTTGCACTCTCGGCTGCAAAGTCTACATCACGGATTTGCGATTCT
GCTGCTTTAACGTTTACTTGAGTTACGGTGATGTTGTTTATAGTTGATGTAACTTGATTTTGTACCGAAC
CAATGTCGGCTCTGATTTGATCAAGATTTGTTATAGCTGTTTCAGCTATATCCATCACAGCCATAGCGCC
TTTAAGTGTGGTAACACCTGCTGTTTCATCTTTTACTCCAAAAGCAGTTGTTTTCATAGTTGCAAACTGA
GAAAGTGTTGAACCACTTGAAAAACCTGAGCCTGCAGAAACATTATATACCGTAGAAAGTTGCGAAGCAG
CTGAAATAGCTATAGCGTTTGCAAAACCTGTGGAATAATTTTTACCGCTACCTACAGAATAACCTGAACC
TGAAGAAAATCCACTTCCTGCGCTACTCATATAGGCACTAACAGAAGAATAACCACCTAACACAACTCCT
TTGTTTGCAGAACCAAATCCCATAGCATCAGCGATATTAGCATCAATTTGTCCTTTTGACTCTCTTAAAG
AAACAGAAGCTTGAGAGATAAATTGAGTTGCACCAAAACCTGCAGAAGAAAGATTGCTACCGCTGATTAA
AATATCTTTACCATCATTTTTAACTAAAGACAAGCGGCCATAGTTTTCTTTCATATCAGCATTGATAAAG
GCACCTCCACCTATATTACCATCGATTTTAATCCCTCTACCTTCTCTTGAAGTAAGTAAAAGTTGTCCAT
TAGCATCGATCGAAGCTTCAACTCCAGTGGTATCTTTAACCGAATTGATTGCAGCAACTAAGGCTCCATT
AGCATCACCATCTTTGTAATCTACTTTACCGATTTTTACCCCATTGATAGCAAAAGTATCTGAAGTAGCT
CCTGCTCTAACTGCAGCTATACCTCTAGTTTCTACTGTAAAAGTAGCTCTAACACCTGTTTTATCAGCAT
TTTTATTGATCTCATCTGCTAAAGCTCCAAGTCCTGTTCCAACTGAAGTTGAAATCACAACTTTTTGAAA
CTGAAAATCATCTATACCATTGTAATTTTTAAGAGTAAATTGTACTTCGCCACTAGTTGAAATTCTTCCT
CCTGTTTCAAAGCGTGTTAAACCTATCTTAGAAGATTGAGTTGCTCCTATAGTAGCTTTTACAGTTTGAT
TTGAACTTGCACCGATTTGAAATTCTTGATTGATAAAATTCCCACTTAAAAGTTGTTTACCGTTAAATGA
AGTAGTATTTGCAATATTGTCAAGTTCTTCCATTAAACGGTTGATATCTGCTTGAAGCATGGTTCTTGTT
TTTAAACTTTGTCCATCTTGAGCCGCTTGAGTTGCCTTAGTTTTGATTGTATCTAAGATTTTAAGTTGCT
CATCCATAGCCTTATCAGCAGTTTGTAAGATACCTAAAGCATCATTACCATTAGATATAGCTTGACCTAA
AGTATTAGCTTGAGATCTTAAACTATCTGCTATCGCCATCCCTGAAGCATCATCTGCTGCGGAGTTGATT
CTAAGACCTGAACTAAGTCTGCTTAAAGAAGCATCTAAACTTTTACTATTTAAATCAGCGTTTGCTTTTG
CATTTAAAGCTGCAACATTGGTGTTAATACGAAATCCCA

Protein Sequence
>YP_002344727.1 flagellin A [Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819]
MGFRINTNVAALNAKANADLNSKSLDASLSRLSSGLRINSAADDASGMAIADSLRSQANTLGQAISNGND
ALGILQTADKAMDEQLKILDTIKTKATQAAQDGQSLKTRTMLQADINRLMEELDNIANTTSFNGKQLLSG
NFINQEFQIGASSNQTVKATIGATQSSKIGLTRFETGGRISTSGEVQFTLKNYNGIDDFQFQKVVISTSV
GTGLGALADEINKNADKTGVRATFTVETRGIAAVRAGATSDTFAINGVKIGKVDYKDGDANGALVAAINS
VKDTTGVEASIDANGQLLLTSREGRGIKIDGNIGGGAFINADMKENYGRLSLVKNDGKDILISGSNLSSA
GFGATQFISQASVSLRESKGQIDANIADAMGFGSANKGVVLGGYSSVSAYMSSAGSGFSSGSGYSVGSGK
NYSTGFANAIAISAASQLSTVYNVSAGSGFSSGSTLSQFATMKTTAFGVKDETAGVTTLKGAMAVMDIAE
TAITNLDQIRADIGSVQNQVTSTINNITVTQVNVKAAESQIRDVDFAAESANYSKANILAQSGSYAMAQA
NSVQQNVLRLLQ

Molecule Role Protective antigen
Related Vaccines(s) MBP fused on Campylobacter FlaA (MBP-FlaA)
References