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PLB

Gene Name PLB
Sequence Strain (Species/Organism) Coccidioides posadasii
VO ID VO_0011327
NCBI Protein GI 74486661
Other Database IDs CDD:214474
CDD:132842
Taxonomy ID 199306
Gene Strand (Orientation) ?
Protein Name phospholipase B
Protein pI 6.85
Protein Weight 65081.68
Protein Length 710
Protein Note Cytoplasmic phospholipase A2, catalytic subunit; smart00022
Protein Sequence 
>ABA12208.1 phospholipase B [Coccidioides posadasii]
MRPIGAAVNALLTAALLAGTAGASAIPLDSNVHIRALPNAPNGYTPANVPCPANRPTVRSAASVSPEEAR
WLEKRRKKAMSALAGFFGHVSIPDFDAVAYIGKYAENLAQLPNIGIAVSGGGYRALMNGAGAIKAFDSRT
AGSTSKGHLGGLLQSATYLSGLSGGGWLVGSLYLNNETSVDALTSGMEGKAWDFHRSIFQGPKFTGSTFL
DVLRYYAQLQSAVAGKQDAGYKVSITDYWGRALSYQFINAKEGGPSYTWSSISLSSDFQNAEYPMPIILA
DGRNPGEKLILGNATVFEFNPWEFGTFDPTIFGFVPLEYLGSKFQGGVLPSSESCVRGFDNAGYIMGTSS
SLFNEFALRLDEVDIPKFIKDELRKILKALGDENNDIADYSPNPFYQYATGTSPFAGVLSLPLVDGGEDG
QNIPLHPLIQPARKVDVIFAIDSSANTKNNWPNGSSLVAAYKRSLDPSGIANGTSFPAVPDVNTFVNLGL
NTRPTFFGCDSSNTTKPTPLVVYIPNYPYTTWSNISTFTLATPNETRDAIIKNGYDVATMGGTTGEKEWP
TCVGCAILSRSFERTGIAMPAACQECLKKHCWDGTVNSATPADYAPSVGPPSAGAKSAASARIRASPSKH
SVVVFSVVVLGIAASW
Molecule Role Protective antigen
Molecule Role Annotation C57BL/6 mice immunized with rPlb showed a significant reduction of the fungal burden in their lungs at 90 days postchallenge compared to the control mice at 15 days (Tarcha et al., 2006).
References