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par1

Gene Name par1
VO ID VO_0011301
NCBI Protein GI 2209137
Other Database IDs CDD:282940
Taxonomy ID 5693
Gene Strand (Orientation) ?
Protein Name paraflagellar rod component
Protein pI 4.95
Protein Weight 64852.11
Protein Length 665
Protein Note Paraflagellar rod protein; pfam05149
Protein Sequence
>AAC32021.1 paraflagellar rod component [Trypanosoma cruzi]
MTVYHEQFALVPPQYPRRAVQEAENHRALAALYELVENAIATAENYVAYTEGRLVPLSSRGSELLAASKE
LRERYRHEAPCGWTEQKVMQHCEQEVTVEEMAELLLRPPLDVAGIRSILRTLQETRTQLPRGRFLLMRDN
LSALKPHQPPDLARDLSDVCGALYEIQYVDLMAELRAELSELDGERDKVQEKLKDAIHLYERAVAKGDVV
EVERAHRQLIAARYEFVNACAKLMHQILGEDMASQESGFAAEMEALRRDAADSISRFAEALHERRQAFRN
DLHNCDKKRLEEDGNHQKCLEVYNAEERETAAQIGQIVEQKKKLVEELRQKARELRDITLKQKEMVEAQV
RAKRAEEERVTAYNEFVNMEEQQKHRLLRCLAYFDGMEELTADLRSYVDEMVTRIPQQNLRQVLDQLNDI
EAEVFMNAYGGFVSCCGELTVKKMHRLDTLERQARLLEHNRDSAMESLDPNMSNYRLELDDIIEQMKGVS
GVINALNATQDAGEQLFQSVEKGVLAKYERSGTPFVHPLQEYGIKSVEERNRFVDRSMHYVENEERKVLE
KRNVLNRMRQAVEEDEAATESAIRNLNEEPAAPEY

Molecule Role Protective antigen
Molecule Role Annotation C57BL/6 mice were immunized s.c. with recombinant PFR-1 (PAR1) protein co-adsorbed to alum with rIL-12. rPFR-1 immunized animals were able to successfully resolve parasitemia by day 30 p.i., with the peak parasitemia occurring between days 17 and 21 p.i. (Luhrs et al., 2003).
Related Vaccines(s) T. cruzi PAR1 Protein Vaccine
References