VIOLIN: Vaccine Investigation and Online Information Network

P36/LACK
Gene Name	P36/LACK
Sequence Strain (Species/Organism)	Leishmania infantum
VO ID	VO_0011284
NCBI Protein GI	134085114
Other Database IDs	CDD:238121 CDD:293791 InterPro: IPR001680 InterPro: IPR011046 InterPro: IPR015943 InterPro: IPR017986 InterPro: IPR019775 InterPro: IPR019781 InterPro: IPR019782 InterPro: IPR020472 UniProtKB/UniProt: P62884
Taxonomy ID	5671
Gene Strand (Orientation)	?
Protein Name	activated protein kinase c receptor (LACK); p36 LACK protein
Protein pI	6.77
Protein Weight	33141.22
Protein Length	413
Protein Note	guanine nucleotide-binding protein beta subunit-like protein
Protein Sequence	>CAM69515.1 activated protein kinase c receptor (LACK); p36 LACK protein [Leishmania infantum] MNYEGHLKGHRGWVTSLACPQQAGSYIKVVSTSRDGTAISWKANPDRHSVDSDYGLPSHRLEGHTGFVSC VSLAHATDYALTASWDRSIRMWDLRNGQCQRKFLKHTKDVLAVAFSPDDRLIVSAGRDNVIRVWNVAGEC MHEFLRDGHEDWVSSICFSPSLEHPIVVSGSWDNTIKVWNVNGGKCERTLKGHSNYVSTVTVSPDGSLCA SGGKDGAALLWDLSTGEQLFKINVESPINQIAFSPNRFWMCVATERSLSVYDLESKAVIAELTPDGAKPS ECISIAWSADGNTLYSGHKDNLIRVWSISDAE
Molecule Role	Protective antigen
Molecule Role Annotation	BALB/c mice immunized with a DNA vector expressing p36/LACK of Leishmania infantum followed by a booster with VVp36/LACK induced significant protection against Leishmania major infection (Gonzalo et al., 2001).
Related Vaccines(s)	VVr expressing L. infantum P36/LACK
References