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KDR

Gene Name KDR
Sequence Strain (Species/Organism) Homo sapiens
NCBI Gene ID 3791
NCBI Protein GI 11321597
Genbank Accession AC021220
Protein Accession NP_002244
Taxonomy ID 9606
Chromosome No 4
Gene Starting Position 55078480
Gene Ending Position 55125594
Gene Strand (Orientation) -
Protein Name kinase insert domain receptor
Protein pI 5.64
Protein Weight 140612.24
Protein Length 1356
Protein Note Also known as FLK1; CD309; VEGFR; VEGFR2
DNA Sequence
>NC_000004.12:55078480-55125594 Homo sapiens chromosome 4, GRCh38.p12 Primary Assembly
CTTCAAGTTTTTCAATGTTCTTTAATAAAATGACATCAATTGCTGAAAGCATTATGACCTTTGTTATGCT
ACATAATACTGATACAAAATGTGAATAGTACAAAGTTCATTATATATAAGGCTTTAATATATTACATTTG
TTTCTACATAAACAGACTATAAATATATGTGCCATAGCATGTCTTATAGTCATTGTTCCCAGCATTTCAC
ACTATGGTACCAAACAAAAAACACATTTTCTTTTTTGAAAAAAAGGACAGAACAAGGGCAAAAATCAGTA
GAAATAGCTCTATATGTTAAAAGTCTAAATAATACAATAGATGTTATAATTTGGGCTATAAAATAATTTT
GAAGTCTGGCTAATAATCATTCAGAGAGTGAACAAACCCAATCAGGTTTACTGGAGTAGAGGCCAAATAA
CTAAAATACTGATGGGTTGCGGGGTGAGAGTGGGTTGGGGACAGGGGGAAGAACAAAAGGGTAAAATCCT
TCCTGAAACTTTGACACCACACACAGCTTCACATTGAACCTCCCGCATTCAGTCTCAGACATATCACATC
AGGACAGATATGAGGGTATTCATTCCAGAAGAAACCAGAAGCTGGTTTGTGCAGTCAGAACTCTTCAACA
CGGCAGGGAGCCTTGAGCTGAATGTCCTTTCTTTGTGGTATTCTGAATAAAGGATCAGCCTGGGAGACAA
GGAGCCAGAGCTGCATCATTTCCTTCCTGGGGCTTGGCCAGGAGACACGTAACGGTCTGGAAGGAACTCT
CATTAGGAGTCAGAAACAGCACAACGAACTCTACTTTAGCCCAACTCGAAGAACACGCAACCTTCTAAAA
CCAGAAACCCCGTCTGAACCCTTTACATTTCAGAACAGACCCCATGCCCACCTCCACCAGAGCAAACACA
ATGCATTTGCAGGCTCCAGTACTCTCCAAAGCAAGGTAACGTTAGTCTTCCTTTCTATCAATCCGAATTC
CACACTTAAGGCTTGGCTTGGGACCCACGTCCTAAACAAAGCCTCTTGGATAGACTCAGCCCTGCAAATC
CTTCCCATCTTCAACACCTCGAACACTTACATTGCCTGGTTTATCTTCTAGTTTTACAGAAGTGTCAGCT
CCCCAGGTACTGCTACTTCTTTGAGGATGGGGCCATTTCTTGAACGTCTTTGTTCTAAACCCATGGTGAG
ACCCGCAGCAGGGGGCATGATAAATGCTTTTTAAATGAATGAAAAAGAGGATCAGGTCAACACTGGGAGA
AGACACAGACACATTCTTGGGTCACAAGCCTCTTCCAGGATATGCCTAGAAGACTGGCTCCCTGCAGTCC
GAGGTCCTTTTTCTGTTGTCGAAATGAAAATCAAATGCGGCTACTTCCTGCTGGTGGAAAGAACAACACT
TGAAAATCTGAGCAGCACCTCTCATGTGATGTCCAGGAGTTGGGGGTGTGGATGCTTCCTTTTAAACAGG
AGGAGAGCTCAGTGTGGTCCCCGAGTCAGGCTGGAGAATCTGGGCTGTGCTACCGGTTTGCACTCCAATC
TCTATCAGCTTTAAAAGTTCTGCTTCCTCACTGGAGTACACGGTGGTGTCTGTGTCATCGGAGTGATATC
CGGACTGGTAGCCGCTTGTCTGGTTTGAGCCTTCAGATGCCACAGACTCCCTGCTTTTGCTGGGCACCAT
TCCACTGCAGAAGAAATGGCAAACAAAGGAGTTGGCAGAGAGAAGACAATTCTTTTGCTTTTTACCCTCA
CCCCATTCCCAACTCCATATGGCTGCCATCTCCCTGGAGACCGCAGCCCCGTATCTCTCCCAGTTGTTAA
TCAGCATAGCAGGTTTACAGGGACAAGGTCTATTTTCAGGTACTCGCATGAATTAGTAGTTGCAGATAAG
TCCTCTTACTCAGGTCCAAGTCTTTCAAGCCTCAAATGAGATGAAAGGCAGTTCTCTCGAGTTATGCAAA
GGCCCCAACTGATGGAACATGTTTATGGCCTCGCAGATTGACAAATTTGTATACAGTGACAGGCGCCAAA
GGGCCACTTGCATGATATTCAAGGAAATTGGGATGTTCTTAAATTTCACTTGTGCTTTTCCTATTGTGGC
AATTTGGGAATTACGGGGCATGTGTATGGTTGTAATAAAGCTCTTGAGCAACTTTAAACTTTAATAACTT
GAAGCATGTGTGCAGTCAAGCCAGACATATCAAACGCTGCTTTTTACTCATCAAAACCACATTCCTTGGA
AGGACTGAGAACCCCTGTCACTCAGCAGCAACTAGAAAATGTTTTCAATGGCATGGAATCCTGACAGACG
GTAATCATGTCAAAGCCTAGAAATGCAGGCTGTGTTGATCTAAAACTTCAGGATTTACACTTTCACAAGC
CATTCTAAGGTGTTTTTTCCCGGTAATAGGTGTTTTCCCCAACTTCTTCATGTTAAAACTGCAAAAGGGA
ATTTTAGTAACTCGTGTTTATACATAGTTTAAAAGTTACTTCAAATAATGAGAAATACAATTTTTTCTTT
CAATTCAACCCCAACAAAACTAATGTAGGTGTCTCAAGCAATGGCATGGTGCTCTGCACATGATACTTGC
CGAATAAACATTTTTTGAATCAATGAATGAAACATATCATTGACTTTCACAATTTCTTACCTTGGGCCTT
AAAGAAAACAATAAAATAGCACAATGGCACCTTTTAATATGTTGGGGTTTTTTTTGTTTGTTTTCTTTTT
GGTATGAGCATTATTCAAAAACCCATGAGTATTCCCATTTTATATAAAAGATTATAAGCAGATCAAAACC
TCCTCTATTCTTACCTTTAGGTAAGAATACTCTAGCAAATAAACTCCAGCAAATACATAACTACACTTAT
TCTATTATTCTTATAAATATAGATTTTCATTGATTTGTTATGTTAAGAGAACGTACACGTATTCAAGACA
CCTACAAATTCCTACTGAGCCATAGAAGGGAGATTATATTTAAAACTAATTTTAATACTTTTCTCACAAT
GAAATACTTCGAATTCAGACAATAATATTTAAATGTCTCAAACAAATAGATATTGGCTTATTTATATATC
ATACTTCTTAAGCACAGATGCACCCATTTGTATACAGACTTAAAAATTCTTCAGAGTCCACAAAGATTGT
AATCATATTGACAGCTTTACGGATCACATCCAATCACCTTTTTCATTTAGCCATTACTGACCACAGTAAA
TATACACAGAAATTCCCTAGTATTCATGAATTCTCATAAAAATTGACCAAATTCTCTAATTTATTTCAGA
TTATTTTTAGATTTATCACTTAATTTTATTGTGTGGTTAGTTTCCATTCTTTATTTGTTAAATTGATGCT
AATTTCTCCAACCAACAAAGACCCCATAGGGAAAATTCTGCACTTACACTGAAAGTCCTAAGTTCCTTCC
AAAAATTCCTATTGAAATTTGTCTTTTTAATATGGCTGAGTCTTACCCAAAAGATGGAGATAATTTGGTT
CTGTCTTCCAAAGTTTTCAGCTCTTCTGAGGCAAGAACCATACCACTGTCCGTCTGGTTGTCCTTTTTAA
GAGACAATGAGATGGCACAGTTAATTGAGCATATAAAATGACCAACTATTTAATTAAGCTGATTTCTCAA
CCCATCTATCATGTCTATCAAATAAGGTCCTGTGGAAGAACATAAAGGTATCATAGCCACAAATTGTCCA
AGCTACAAAAGGAAGCAACTGCTTCCTATGAGTAGACACAGGCCAGGGAGAAGAGAAAATTTACAAATCA
GCAGCTGAGAATGCCTGTTACCATCGCTGTCTTCACTATGACACTACTTGCACTTTAGTGAAATTGGTCA
GAAAGCTACACTGTCTTGAACCTTGGACCAAGGGCTTTACTTATGAAAAAAACAAAGTTCCATCTCCATA
ATGACCCCATGATACACACACTCGAGGGCAGCCTTCTAATGAGGCTCCAAAACTTTAATGCTTAGGCTAA
TATTTATCTAGCTAGTGTTTCATCCTTTGTATTATTTCTAAGACTATTTTTAAAAGACGTACTTACATCT
GGGATTACTTTTACTTCTGGTTCTTCTAACGGGATATCTTCAAATGTTTTTACACTCACAGGCCGGCTCT
TTCGCTTACTGTTCTGCAGATACTGACTGCAAAAGAACAAATATTTATATTTTAGTGGTGGTATATTTGA
CTGCAGATCGGCTACCTAAGTTCATTATCTTTCAACCACAAACTTAATAGCAACCTTCAAAACATCCTTT
AGAAAAACAAAACAAAATAAAAATCTTTCTCTGCTAGCACACATGGAAGGCTTAATTTCCTGAGAAAGTA
CATTTAAAAGTATAATATAACTGAGGAGTCTCGATGAGCCTGTTCTTTTGAATCCTACTTCTGAGGTCCA
GTTCTGGACTAAAGACAACAACAGCAGATGGAGTGATCAACTGCCTTCTACTTGGCTTCCTGATTGCATG
GGATTCCTCCATCGAGCTCTGGATATATTACTGAGTGTTTCACATCTGTCTGGCCATCTCCTGGGAAAGT
TTTTCTGGATAATGCTCACAGAGCAACCATTCAATGAAAGATAGGCAGAGGAAACATCTGAAGGTCTCCT
TAAAGGATACTGAACCCAGCAGTGATTTGAAGACAACCTCTTCCTCCTCCATGTAACAGAGGCTTGGTGT
GCAAAGAGAAGGTGGGCTGAGTCTCACTGTCCCCTCGTTTTCGCCCCCAGAGTTGCTGTCTCAGGAAAGA
GCAGTGGTTTGAGAATAACAAGATATTTTGCCTATTTCAGAGTCTACCACTGACTGCAGAAACTTGAGAA
AGTCATGAATATTTCTGTGACCCTCTTGTCCCATCTATAAGATGTGTTGGCAGTAGCACTCCCTCCCCAG
CTCACAGGGATGTTGGGAAGATGAATGACATAGAGAATGTTGGGCTTATTGCTCTTAGGAAGAATAATGC
CCTCTTCAAACAAAGCTCATTTTTCTCCTTTGACTTCCAAAGCTTCCTTCAGGAGTCCAAAGAATAAGAC
TTGTTGAACAACAGATCCTCTCCTTCTTGAGAATGCTCCTTCCCGGCCGTGTGGCTTTGGGTGAGTCTAG
TTGATGCTATCAAAATCACTTACAGCCCAAGTGGAGGGAAGGGAAGTCCTATTCACTGGAAGGGCCCACC
GAGACAGAAAATACATTCTTCATTCCTATACCAGCCTACTTCCCACTACAAGCAGACTTCTGGAACATGC
TGCATAGACCTTGGGCCAAAGGAGAAGAATGGAAATTAATTCTCTCTCCCCTACCCCAAGAGGCTGGTTC
CTCCCTATAGAGAGAGGAGAGAATGAGATTTTCCGGTGACATCCTCACTCAGGAAACTCCACAAGTTAAG
AGGATATGATACACAGGGTGCAAGCAAAGCCTACTTTCTAAGTCCAACCCCTAAAAGTAACAGTTGTCAA
ACACTACTGGTACCGTAGTCAATCATTCCTGCATTCACTTGTTCAGGAAGCCCTCACTGATAATCTGCCG
CAAGCCTGACACTGTGCCAGAAGCTGTCTAAGCAGCATCTCATGATGTGTTCACCACGGTACCTCTCTAG
GGGTGAGTATTACTATCCCAACTCTTCAGATGAGGAAACCAAGGCATAGAAAATTTGAGGAACTTATCCA
AAATCACATAACTGGAATGTTTGGATTATTATTTTGAGGGCAATGAAGAGCCACTGAAGGATTTTAGGCA
TGGGATTGACAAGATCAGATATGCCCTTTAGAGAATTGACTCTGGATTGAAAAGAATAAGACTAGAGGCA
TAAGACCCAAGAGACAAATACTGCACTTCTTCAGGAGAAAGAAAGGCAGCTTGGCTAGAAAAAGGGAATG
CCCATGAGGTTTGGAGACATGGGCTCATTCTAGAGATATCTAGGGGATAGAATCAACTAGGGTTGGCGAG
TTTGGACAATAATTCAGCTGCCTTAGAAAGGACAGCTCCTTAAATTCTTAATCCAGTAATTTTTTAAATG
GCATGATCCTCTCATGATTGACAAAGCATTTTCACAGACAATGGTGCATCTGTTTCTCCTAAGACGGAGA
AACAGGTCTTTTAACTATTTCCCCTTTGGAGATGAGGGAGTCAAGGATTAGGGAGAAAATGGCTAATAAA
AGGTAGAACTGGGACTCAAACTTAGGCCTTCAGACACTAAAGCCCATGTGAAGTTTTTGTTTTGTTTTAC
TCTACTCCATACAGACTCCCTTGGAAGAGTATCAGGAGGGAAAAGAAAGAAGAAAACAGCAGACACAATT
GTTCAAGCCATTATTAAGCACCCAGTATGTGCACAGCACTGTTCTCTTGTCATGCATGCACTGATCATGC
AGTAGCAGGGTCAGGGGTGTAAGTACGGGGTATGAAACAGACAAAAAGTGCAGAAAGGACAGTCCCACTG
CAAACAGTCTAATGGTAGAGCCAAACTCAGGAATACCTAGCTAGCAGGCTGCCCCAAGCATCAATCTACA
AGGGCCATTTAATCATCCCTAACAATTACAAAATGAAGAAAATGGTATGTACCAAAACCTTTCTCTAAGA
GAGAACTGCAAAGAAATTTTTGATAAGCTGCTTGATGTGTGAGGTGAAACTCCCAGGGAAAATGACAGAG
CAATTGCCGATGGTCCCCAAACTGCCCTCAAAGAAAGATGAGCCCAGCAAGTATGTGTTTTCTTGCAGGA
AGCATGCAAACTTGAGGCCAGAGCTGGTCCACAGGGGAAATTAGAGGCAAAGCTAAGTCTAGACATGAGT
GGTCCCTCCCCCACACACTTCTCAGCCTTTTCTCTAAATAAATGCTAAGTAAATATTTTTCAAATGGTTT
AAAGGGGCAACAAATCATGAAGCTAGCTCCCACAGTGATATCTCTGTCCAACTCTATTTATAATGCAATA
GAATTGAAAATTAGAAGGAGAAAGACTGCTCAGCTTTTGTACTTGGCCAGAAATGCGTAAGAGGATAGAA
CAAGCTCCCTGAGAAGTACCCCAGCCTCAACTCATTCTCCCCAGAGAAACAGAACCCCAGGAGAGCAACA
GAATGAAGCATGCCGTGTGCAAATGCCTCTATCTGCTTTTCTTCAAAACCAGATGATTAAAATGTGACCG
TGAGTTTTATTTTATAGAAAGGAAAAAAGGTGGAGGAGGTGGAGAGGAGATGCAGACAAAAGATTCCAAT
TTCCATTTTATTTTTCAAATTATGGCTGGATAAAAGAGAAACTGGGCTGGAAAAACCAATTCAAAAATCA
CAGACAGAAAATAGGAGCCAGGCCTGTGCTGGGAGTGTGGTGTCACATTTGTCCACGCTTCTGGGGATAA
ACGTTAGCAGCCCTTCTATATATCCAACATCGTATTTGGTGCTTCCATTACACAAACATGATTTCTTCTC
CTGCTCAGCACCATATGCAAAGCACCCGGTGAGCCAGGAGGCTGCCGACTCGGATCATCACTCTACTTGG
TCACAGAAAACACATGGAATGTAGTTCATGATCAAATGGCTTTCTGATAAAGGGGGAGGCAATAATGGTG
TGTGGGAACAACTGTCACACTAAAAGGCCAGCTCAACTTGAACTGGAAATGTGTAAACACAGGAGTGGAA
TTGTAGTCTCATCTCATTACTGTTTCTCTCTGAGGGCCCTCCTTGGCATGGGAGGAAACAACATGGACTT
AGGGGTCAGAGGAACTGGATTCATCTCAAGGATGTGATTTTAAGCAGCTCACTTAATAGGTATCTTTTAC
TGAGTGCTTTCAAGGGCCAGGTGCTTAGAAATAGATTATATCTTATAACTCTCAAAACAGCCATTTTCAA
ACAGCACCACTGACCTTGTCTCATTTCACAGATAAAGAAACTGAGGCAGAGGGTAGATGATTTGCCCCAA
GTTGCACAGCTGCTACAAGACAGACTTGGGGGTCCTACTCATTTCTATCTGACTCTAATACCTGATCTTT
AACTACAAGTTTGTACTGCCCTCAGGTAATAGAACTGAGCCTCATGTTCAATAATACATCAAAAAAAAAG
ATCATTGTTTCTACCTTGCCTGACTCTGAGTGTCATGATGTGGGCAACATCTGATAATATACGGCAAAGT
TCTTTAAAAATATGCCTAATGCTTTTGACTTCAATGGAACGGTCAGCTGTCTTGCTGGCTTCTAAGCTTT
CTTCCTTCCCATCAGTGTTTCTGCTGCCCCACACGACTCTAGAGGGCAAACTGTCCACGAGTTTCTCCTT
AGCATCCCCTGCCATGTGGCAACCTGGCCAAGTTCTGGACATGAGAGAGCTCCCTGCCCCTCCCTGCAGC
CCAGGCACACTCGGGCTGGCAGGCTGGACCCATGCTGTCAGGGGTTCCATTAAAGCAGGAAAACACCCAA
ACGGGTTAGGAAAGAAACAAAGCAAAATGAAGTAGTCCCAGCCTTAGTAAAGGGCAATTTTAATATCATA
TTGTAGAAAACCACACCAACTCTTTCCTTATGCACAGGTGCTGGGAGAGAGAAAAAAGAAAGCTGCCTTT
AGAACCCCTCTGCAAATCAGGAAAGGACTGCAGTGCATGTGTTTTAAATAAGCCCAGACATCCCATTATG
CAAATAAAATGCTGAAAATCAGACGTGGGAGGGGCTTCTGAGATGCAGTGTCCAGTCTAATTCCGGACAC
AGACCCATGGCTTTCTGTATCCTTGCCAGAGAGCCATAAGCATGTTCTCATGCAAGCACAGAACTCTTCC
TTTCTGAATCTCTCCTAAGCCATTTAATTCACATTAATAAAAGCATACACGGGGATAATTTAAATGCAGA
TGTCTTTGTAAAACTCGTCTCTTTATTCTGGAAATTAGCAAACTGTGGCATTCCAGCTATTGCAGCTGCA
GGGCTTGGAATTCTTAAAGGCAATGCTGTGGCAGCAGCGTGGGCTACAGATGGGAGGAAGCACACCTACC
CAGGCCCTCTTCCAGGAGCATTCCCCATTATGTTAACCTCAGGGCTAAGGTTATGTGGAAGTGGGATGCA
ACAGCCTTAGACAAGGTCTTCCTTCCACTTCCAATCCCCCTCCCGAGATGGCCTTGAAGTCACCCTCCCC
CGGGGGATGTTAGGCCATATACAGTACCTGATTCCTGCTGTGTTGTCATAATGGAATTTGGGGTCACATA
CTTCCTCCTCCTCCATACAGGAAACAGGTGAGGTAGGCAGAGAGAGTCCAGAATCCTCTTCCATGCTCAA
AGTCTCTGATATCGGAAGAACAATGTAGTCTTTGCCATCCTGAAACAATAAACACAGAAGACTGTTGTTA
TGGCTTCAGTTCTTCAAGTGCCTTTTCATTAAAAACAAAGGGCACAGGGACTTCTTGGCTACATAGGGTG
TGTGGCTTTCATATCTGAACATAGAACTTTAAGACAACAATACAAATCATGTGTCAGAAACAAAAAGCTG
TTGAAATGGAAGGTATATTAAAGGAGAGAACTAAAAACAAGATGGGTAAGCAGCCCACAGGGAAGTGCAG
TTACAATGAAGAGAAAGCAGGCTGTGGTCAGAGAGGTAACAACAGAACACAAGGAGCTACATAGAACAAA
AAATCACTCATTCACAAAGCCCTAACCACACGAGCCAAGCCCTTCAAAGGGCATGGCATCCAGTTTTAGC
CACCACATTTCAAGGCAATGGAAAAACTGATGACAGTCTAAAGAAAAGCAACAAATGGGTAGGAAAATGG
GTCTTTTGAGAAAAGGTTGCACAACTTAATATTATTGCATCAAGAAAAAGAAATAAAGGGCTATTTGATA
TCTGTAAATGTTTGGAAGGTTTATTGATAAAAATAGAGCTGACCTATCGTCCCCCAGCTGTTCAAAAGAA
AAGAAAGAGGAAATTCACTTCCATTGTAGTAAGAGGCATTGACTAGAGATTAAATAACATTCTAATAGTA
AACACTACAACTCTAAAATCTTCCAGTGGAAGTTATAAGAACCTGGGATGATACCAAGACAGAAACCATC
TCTTTTGCATAGCTTAGATGTATTTTTGCCTGCAGAATTTATTAAAAATTTCTTGAAATTTCTTCCATTG
TTGATCTTCTGTGGATCAACCAGATTTTTTCTTTGTTTTAACTTTAGAAGAGGATTTGAAAATATAACAA
AAAGATAAGTAGGTAGAAATCAGAGTGGTCTGCTCCCGGGTTATAAATTAGAATCCTATCTGTCTAAAAG
GGTAATTACAGCTTTTAGAAAAGCATTATTACTCAGATGTAGAAGAATACAGTAGATTATTCAATGGCTG
AGAGGATGGCATGGTAGCCATGAGACAGTTCAGGCAGTAGGAAAGTCCTTGACATCTAAGTACTCTTTGT
AGGTGCTTCTTGGATGGAGGTGACAAACCTGCTGAGCATTAGCTTGCAAGAGATTTCCCAAATGTTCCAC
CAACTCTGAAAACGTGGGTCTCTGACTGGGCTCCCCGTGCCAGCAGTCCAGCATGGTCTGGTACCTAGAG
AAGCAAAACACTGATTTCATTAAATGCCTCTTTCTTCCTGAATGCTGAAAATAAGCACTTAAATGAGTAC
ACATTTGTAAAGAGCTGACGAGGTGAGATGCTAAATAAGGATACAAAACTGTGTAAGACACAGAGTCCCA
TACTCCAGAGGCTCAATGTGTATAGAAAACATTTAAAGCAACATCTAATAAAAACTAACTGGTTGCTTTG
AATAATAAAGTACTATCTTTTCAAGAAGTGATGACTCCATGCTTGAAATTATCAAGAAAGGCCCCAAAGT
AAAAGCAGGACACTAACTGGGCAATGAAGAAGGTCTATATAATGGAAAGTCTTCCAGGCAAGGAGAATTT
GCGAGCAAAGAAAGAGAACACAGGAATACTTCTTAAAGTCTTACATTTCTGGTGTAGTATAATCAGGGGC
CCTCATTCTAGTTCCTTCTTTCAATCGCCTACAAAATTCTTCATCAATCTTTACCCCAGGATATGGAGAA
GCACCTAGAATAAAACAGGGAGGAGACATTCTTTGATTTGATTTTCTCTTATAGAAAACCCTGAGCCTGA
ATCTTGCACATCCTCATCACCTATGTATCTATTTTTTTTTTCAAAGCTTCCGAGAAGTTTTGCCTGATAG
ACATGAAGTACAGGAGAGGAAAAGACAACTTTTGTCTTCCTCTTTGGAGTCTGGATGGAAGGACAAAAAG
AAATGACTTACCTAAGGAAAATATTTCCCACAGCAAAACACCAAAAGACCAGACGTCACTCTGGATTGTG
TACACTCTGTCAAAAATTGTTTCTGGGGCCATCCATTTCAAAGGGAGGCGAGCCTACAGGGGTAGAAGAC
AAGGATTCAGAACCCAAATTAGCAAATATCTGAAGAAAAAAACTTCCTCTGTTCCTGAACACAGGTCCTG
AAGCTCTCTACGAGGAGTTTTAATTCTGTTACTTAACCAAGCACTGGGTTCATATTTGAAACTTACATCT
CCTTTTCTGACATAATCTGGATCTTTATAAATATCCCGGGCCAAGCCAAAGTCACAGATTTTAACCACGT
TCTTCTCCGATAAGAGGATATTTCGTGCCGCCAGGTCCCTGTGGATACACTGCAAAGAGAATCATGTGTG
CATTAGGTCTCGGCACAGCTGATCTCTTTCACATCTGTTGTGACCTCATGCATCAAAAAAAAATCCCACA
TCAGAAAGCCAACTGATTAACAAGGACTGGGTTAGTATCTTTTATCAACACTTCAGGAAAAAAGTCTGTG
AGCTTTGCTGAGACACACATCTGCTTATTCCATAAACAGCCCCAGCCTTTGGAGTTAAATAATTAAGTTA
TAATATGATGATGGAATCATAAATAGGCTCCTCTAGGACACAAAAGAGTGTGTTTCTGGTCACATCCACA
CATTCCTTTTACCTGGCCCCATATTTGGTTTAAAACGTGTTATTCTAAGGAGGTCCGAGAACGGGATTTG
TTTTTTGAATGAATGCACGGAAATCAGAAACAAGGGGCTCTCATTGGTTTAGTGCTCTTTGTTGGTTTCC
CCCTTCCGTATGAAGCTGAAGCCAGACTGGCTCTGATAAACAATTCCCAATGTGGCTTCCCCTGATTTCA
AAGTGCTGGGTTATTATAAAGGTCTATTAAGGCAATTTCAGCCTATCACAAGTCAGGTTGATTTTCTAGT
GCATTAATAGTACAATGAGATTCATCTTGACTTCTTTCTCTTCCTTTTAGCTTCTCAGTTTCTCCTTTCT
CTGTATCCTCCAAACTTCAGCTAACTTCCTACTACTCGGCAGCTTTAGCTCCACATGATATTTTGTAAGA
AAATGAGTCTTGGGGAGCACAAGAAATGAATCAATGGCTTAGAAGAAAACTTTTTTTTTTTTTTTTTTTT
TTTTTGAGAAGGAATCTCACTCTCGCCCAGGCTGGAGTGCAGTGGTGCAATCTCAGTTCACTGCAACCTT
CACCTCCCAGGTTCAAGTGATTCTCCTGCCTCTGCCTCCCAAGTAGTTGGGACCACAGGTGTGCCACCAC
GCCCAGCTAATTATTATATTTTTAGTAGAGACGGGGTTTCACCATGGTGGCCAGGCTGGTCTCAAACTCC
TGACCTCAGGTGATCCACACACCTTGGCCTCCCAAAGTGCTGGAATTACAGGCATGAGCCAACACACCTG
GCCAAAAGGAGAATTCTTAAATCATTGGAGAAGTGATCATGTAAGCCAGGCATTGCTGACCTTCCCACAC
CTCAAATCTGTATGGCACTCTCCTCTGAACAAGGCATATTCAGAAGCACATTATCTAGCACAATTGAGCA
ACACTGGCAATTCCAAAAAACAGACAGTGTTTTTGACTTTTCCCCCCAAACAAAAAGTTTCCTTTTTTAA
CCCGACAACCAAGTGGATTCAAGAAATAGTCTGGTAGATGTAAGGAAAGTTAAAGCATTCCCACATTCAT
TTCCATTCTCTTCCTAGTCCCCAAAAGGAACCCTGACTAAGTGGCGAATTCCGGCCATAAAAAAATGGTA
ATAATAAGTCATAATCTCCAAGAAGTGTAAAGGGCCTTTCTCTTTGGGAAAACCCTATAAGGTCCCAGTT
CTCCTCCTTCCCCTTGGGAGAGAGAACATAAGAGCTACCTAGCAGAAACATCAAAGAGCCTGAGGCCTTT
AATGCTATGAGAAGGGGAAAACATGGGTTGAAGATTTCATTCTAATTTAGGAAAAACAAAAAAAAATATG
ACTTAAGTCTTTCTTTCTTCATTAAGCTGCATGAATACATTCTGTCAACTGATAGTTCTTCCTGATCCTT
AATTTGAAGTATTGTTACCTAATATAAAATTACACCTTTTATCCTTTCCAGGGGAATCACTGCCACCAGC
CTTGCTCCCCGCTTGGTGTTTACAACCTTTGGAATAGTTGTAACTTGTCACGTCCCCATCTCAGCCTTTG
TTTGGCCTACTTTTCTAATTTTAGCTCTTTTAATCGCTCTCATCTGAAGCCTGTCCTTCCTCGTTTCTAA
TTATACTCCTAACAAATACTTTTTGATGGATGTTGATGAATGTAAAATAAATTAAAAATGATTCTCATGC
CAAGATATCTGTAAGGCTCAGCCCCTCCCCTTTCCAGGTCATTGCTCAAATGTCAAGTTCTTAGTAAAGC
CTTCCTCGTCTACCTTGTTTAAAGTAGATGTACACACACAGAGAAGCATAAACATACACAAGTGCATTGC
TCCTGTGTATTCTATAACCCTTTCTTGCTTTATTTCCCCATAGCATTTACTCTCATCTAACCTACAACAC
GTTTTACTTGTTTATATTGCTTATTGTTTGCTCTACCCACTAGAACTGTAAACTCCATGAAGGTGAAGAG
CTTTGCCTGATTGTTCACCACAGTATCCTCAGTGCTCAGAAGACTGCCTCACACTTAGTAGATGCTTGAC
AAGCCTTTATTATACAGCTTAATTTCATGAACTCCTTAACCACTCTTACTCAGCAGAAACAGAGCCTCCC
CAGTAGAGCTCTTCTAAAAGACGTAGAAGTGGTGAATGAATTACAATCCCAAACAAGCACCAATGGCTGA
CACTGGACATCTTATTTCCAAACCTGTGATCTGAAAAGATAGCTGATTTCCCCTCAACCTTTCTTACCTT
TCGCGATGCCAAGAACTCCATGCCCTTAGCCACTTGGAAGCTGTAACAGATGAGATGCTCCAAGGTCAGG
AAGTCCTTATACAGATCTTCAGGAGCTGTCCAAAGAGGCAGGAGGATGGAGATCAGTATTTCCATGAGTT
AGTGTGATGTTTCTAAGTTTGCTAGAGTAATAATCTTTTTAAGACTTGGGAGTTAAGTTTTTAGGAAATA
GAAGCAGAGAGTCAATGCTTCTATCTTCTGTAAATCTCCTGAATCCCAGTATCATTAGCCTTCATCATAC
CCCCTTAGGAACAATACTGGTTTTTCCATTTTAGCCAAATTGAACCAGTAAATCCAGGAGGTAGAATAAG
GTAACACTGACCTAGATAATCTGGGAAATAAAGAGGACATTTCCAAATTTGCCACTTACACTGTTTTTTG
TCATGTACCCAGAGGGATAAACAATAGTTTCATATCAAGAACTCTAAAAATAAAACAACAATATTCAGGG
TCATTGAATCTCTTCTCTCCAGGTTTTGTCCTGGGACAAAGGCCAAAAGTCAAACTATAATCTGCAATAG
ATAACTAAAAATACTAGAAATATATTTAATTCATTTTCAAACTTAAAAAGTGCTGTAAATACATTAAATC
TGGCCTGGGAGGGTGTTTTTTCCTGAGAGATAACAGAAACATGGAAAGATAAATTTACGTAAATTGGTGG
TATTTACTTCAGTGCAACTGGTACAAATAAACACTAAGATATTAAATGGGTGTTTCAAAATCATCTCTTT
GGTCAGATAAGACTTATGGCTTCTTTCCTGGAGACAAATACCAGAGTAAACAAAAACTTAGTTGTAGTAA
TAAATTCGTAAGTATTTAAAAGGCTGTGAGCCTTTTTCTCAACAACTCAATCTCTTAGGTTTCTGGCTCA
CTGGCCACTGTTTTTTGAAAGACAAAGAGCAGGGTAGAGGCAGCACCACTCAGTGTGGGCCCAGCTAAAT
GAAGCCTAGACCACCTCCCCATGTGCTTCTAGACCAAGTCCCAGCCTCACACTACCTTCTCAGCTTCTAA
GGAAAAGGAGTTAAATGCAAATTCTCTCTGTAGCCTCATGTCAAGGGAAACAGAGTGGGTTTCTTCCACT
ATTCTTCTAGACTTATGCCTCAAGGGGAGCCAGCCTGTCACCCATCTCTACATCCACAACGCTATCTCTG
CTCCTTCTGAAGGAGGCAGAAATACAGTGTGTCCTGGAGCCGGCTGAAGTCCTGGAAGTTAGGCTGGGAC
CACAGCTCCACCCAAAAAGAGCACTAAAATATCACTCAGGCCAGGCACGGAGGCTTACGCCTATAATCCC
AGCACTTTGGGAGGCTGAGGCAGGCGGATCACCTGAGATCAGGAGTTCGAGACCAGCCTGGCCAACATGG
TGAAACCCCATCTTTACTAAAAATACAAAAAAAAAAAAAATTAGCTGGGCATGGTGGAAGGCACCTGTAA
TCCCAGCTACTCGGAAGGCTGAGGCACAAGAATCACTTGAACCCAAAAGGCGAAGGTTTCAGTGAGCCGA
GATCGCACCATTGCACTCCAGCCTGGGCAACAGCATGAGACTCCACCTCAAAAAAATAAAAATAAACATA
AAAACAAATAAATAAAATATCACTGGAAACATAACTTAATAAAGGCCAGGATATTTATCAAGACTCGCCT
GAGGAAGTATGGTTGGAAGGAAGACTTGATAAGCCGCTTGGGGTAGGGTAGAAACAACAGATGGCTCCTA
AACTGCCTTTGAGAAGGTTAGGTATAATGAAAAGACTTTTGCACAGGTAAAGCATGCAACGTGGGGCAAA
CCACTCTGGGGCTCTCCAAGGCAATGGAGAGGCTAGTCAACTACCAGAAAACTTGTGGCCTCTCTCACTA
ATAAATGCTGAACCAGTATTTTAAGAACACTGCTGTGGTTGTAGCCGACTGCTTAGCCCACTTGGACTAC
CCAGATTTCTCAGGCTAGCCCTGCTTCACTTCCCAGTCTAGGGCTTCCACACTTCACTTTTGGGGAGACA
GAATGGAGGCAGTCTATTATAGAAATTCAGGTCTCTTTCAAATTATGAGGTAGTATTGGACTTTTCCCAT
GATCAAATTCCTTGTAACACCCTATCACCCTGTCTGCTCTGACAAGAGCATGCCATAGCATGCAGGAAGC
ACTAGCCAGTACCTTCCTCTTCTTCTACATCACTGAGGGACTTCTCCTCCACAAATCCAGAGCTGGCTGA
GCTCTGGCTACTGGTGATGCTGTCCAAGCGCCGTTTCAGATCCACAGGGATTGCTCCAACGTAGTCTTTC
CCTTGACGGAATCGTGCCCCTTTGGTCTATAAAAAAGCAAAGGAACAAACAAACTCCTTGAATACAAAAT
GAGTCTTTAAAAGTTTACAACCTTTAAAATGTAGTAAACCATGGAGATAATTGAAACTACTAAAAAGCAG
ACAAGGAGGACATCAATTTCAGGATTATGCAATCTCTGAGCTGAAACTTGGGGCAAGTTTTGTGCATAAT
AGGGTTTCTTCCACAAAGCCTAGCTCCTTCTTTAGCTTAAAGTGACAAATGCCACATTTTGAGTTGCATT
CAGACACACTTTCAGCATTAGGATGCTCTTCACAGAGGGATTTACACTCCACGGGGCCAAATATGGCTAG
GGGAGAGACAGAATAACCCAGAGATGTCCTACCCTCTGCCCTCCCCTTTCCTCGCTCATACCTGCCTTCT
CCCCCATGTCCACACTCTGTAATGGGTCAGTAGATTAAAATCACATACATAAAACAGAAACATATGGCCC
CCAGAAGGTAAAAGAGGAAGTTACAACAGCCAAGAGGTAATATGAGAAGATTCCTCACAAGTTCTTCACA
AAATTTCAACTAAAAAACTAACCTGTACCATTTTGAGTTTCCCTTCATTTTATAACATGGCCAGAGCAGG
ATTAGGAGATGACATACCTTGTAGGGGACAAATTCATTTCTCTTGCTCCTCAGGTAAGTGGACAGGTTTC
CAAATTTGCAGAATTCCACAATCACCATGAGTGGCCCTGCAGGCAGCATGTCCAGGAAGGAAAATGGGTT
TTCACTCATATTCCTCACTAAGCGTTTAATATAGTGATGAACCCAAAAACACCTTAGAAGAAGGCTACAA
CCTTTCATTGGGACAGGAGTGTAGAAATCAGCTGGTCCCAATCCCCTTATATTGTAGCTTTTCTTTTTTC
CAGAACACATTTTCACAAGATTAACCAAAATTTCAGAAGAAAACCCACCCATCTACTTGCTTTTCAGTGC
AATCTCCTGATATGATTCCATTTTGGGGGTAACTACCCTTAAGCTTTCAAGTTTTAGGGAAGTTTACTCT
TCTCTGGACATCTGTTACACAAGTAACAAACTGTATCATAGTAGCATGACATTTCTTAATTCAGAGAAAG
TTTTACAATAATTTAATTCTAGTGCCAATTAAACCTCCATGAAATATATTTATTCCTAGGAATCCGCAAA
GTATTCTAAGCTAAGAAAATCAAGGCCAGAGGAGTTGACTGCTTTCCCTCAAACACTATCAGAGAGGCAT
GTTAAAATTGGGTGACCAAAACCACCCACAGTTACTCACCTCCTGGCTTGGTACAGGCACCTAGAAGGTT
GACCACATTGAGATGGTGACCAATATGAATGAGGATCTTGAGTTCAGACATGAGAGCTCGATGCTCACTG
TGTGTTGCTCCTTCTACAAATACAGTACAAAGAGGGAAATCATAGGTATGGACATTTCCTTCAATAATTG
GGGTCCCTCCCTCCCTGCATGCCACTATACAACTTACCCTCCGGGGTAACACAGCTGTGACCTAGTTTAC
AGACCACATGCATTTCCTCAAAAGTGAAGTGTAAATTCTATTTTCTAATTTGAAATAAAATTCATATTTT
AAGTGAGCCAGAAAGTTTGATATTTAAAGGAACCCATTGTGAAACCTTTTGCAAAGCGGAGAATACATCT
GCAGTGGAATCATGCCCAGATTCTCTTCTTCTGCAAAACTGGATTTTTGCATTTCAGGTTCACTATGATT
CTGAGGGTCTGATCATTTCAGCACTTCCTCATAAGGAAGCAACACCATGTATTAAATATCTTCACGTGTT
AGGGGCTATACCGAATGTTCCAGCCAATCTGTGCCGATCTGTGCAGGCGAATTAAGGCCAGCTGGAAAGA
CCAGTTGGCACATGAGGCTGATGGCACTAAGACTATGTGTTTGATCCTGTATGGACTGCTACACTTCCCA
CTAATTCACAGGCATGGTCCACATCTAAGGCTCTGATGAGCCACCTCAAAATTACACACTCCCTTGGCCA
CAAGAGAAAAAAGGCAGATGGAGAAAGATAGCTTTGAAATGCACAAAACCTATTGGCAAAGGGTCATTGG
CACTGCCTTCATCAATGAAAGAACATCACAATTGAAGAAAGAAGCTTTACTGTCTAACCTCCTAAAATGA
AAATGGCCAGACCAGAATTCCGTTACTATTAGAATTAACAATTATTTATAAAGCTTTTAATTTAAAAAAT
ATAACCCATTATATTTTTTTCTAACACAACCATTCTTGTTTTGCAAATTATCTTTTACATATGAACATCT
TTTACATATTCCAATTCTGGAGAACATGCTATTTTTGTATTTCACTATCTTCCTTTCCATGTCTCTAGAT
GGTCTATAATTATCTGATTCCACAATATATTAAGAAACAATTTTAATATAACCACAGTCCTTTTTCCCTG
TACCCAGAACCACTAAGTACAACTGTGTTGGCTGAGCCCTGCACGAGGGTAACCAGGCAAGAAGGTGAAA
GCCATTCCCAACTTTGCTTGCCAGACCATGCATCCTGGCATAAAGCTACAAAGGAGGATCCTTTTTCCAA
TTTGCACAAGGGCATTATTTAGGCTGACTGCATGTGTGGCTAGTAGGCCCACATAAGCACAAAGCTACTG
ATACAAGCCTTGCAACATATTTAAAGACTAGATAAAACAGAAAGATAGATCACCACATAATTTTGCTTTT
ACCTTTCAACATTTTGACTGCTACTGTCCTGCAAGTTGCTGTCTTGTCAATTCCAAAGGCATCTGCTTCA
ATCACTTGGCCAAAGGCACCACGGCCAAGAGGCTTACCTAGAGTCAACAACAACAGCAACAAGAAAACAG
ACTTGGATTACTATACAACCAAAGTGATACGCAGAGACATCAACTAGATAGGGTGACCATACATCCCAAT
TTAACATGGATAGTCCAGTTTACTCCTTTGTCCTGGCTTAATTATTTAATAACTCCCCCTTCACTCTCCA
AATGTCCTGCTTTGGATGATTACATAGGGACCCTACCTCTAAGTGGCTATATGAATGATTATACAAATTC
AAGAAATGGAATTAATATTTCTAAACCAGAATCCAACATCTGAATACACCACATTTGTCATCATTCTAAT
GGAGGAAGAGATGGCCTGGTAAACACAATATCAAATTAATAGCAATTGAAAATGCACCTAGCTTCAGCCG
GTCTCTGGGGAATTCCCATTTGCTGGCATCATAAGGCAGTCGTTCACAATGTTCATCCAATGGGAGTTCA
TCTGGATCCATGACGATGGACAAGTAGCCTGTCTTCAGTTCCCCTCCATTGGCCTGGAAAGCATCAATCC
TTCCAGTCATAAACACACTGTTGTTTGGCTGTTGTTTTGTGTGCTTGTTATTGCTGTTTATTGGAGCCTC
ATTCCTGTCTCATTTTCCAATAAAACTCATGGAGTTTGAGAGTGGTCCTATTATAACCCTGCTTCTAGTT
TCCCTTGTCCCCCAAAGGAGCTCAGAATTAAGGTTTTAAAGCTTAATTACACTAGACAGTCCAAGCCCTT
TTCCTCTCTAGTGGCTTCTATCAATTAAATCCCTGAGATCCAGCCAAAAGAAAGTGGGCAGGAACGTTAT
TGTATTGAAATAAAAATGTGCCCATTGAGCCAATAACAATGGGAAGAAACAACTCAAAGAACCCCAGTCA
GTTTTCATTAATCATGAAAACCAATGTGCATGGGCAGAAGGGAAATTATTTTTTTACCCGCTTAACGGTC
CGTAGGATGATGACAAGAAGTAGCCAGAAGAACATGGCAATCACCGCCGTGCCTACTAGAATAATGATTT
CCAAGTTCGTCTTTTCCTGGGCACCTGGAAAGACACAATTGAATGAGTATCAACAGTTGGAAACTTATAC
TTTTTGTTTGTAAGATGACAAATTTTAGCACTAAAGCAAAATCCCAAGCTTACCAACTTGGAAAAATCCT
AGAGGACAACAGTTACACACCCGTAACTTGAATGGAGTCTACAGAATTCTTTTTTTGAATTTAATTTATT
TATTTATTTATTTATTTATTTATTTATTTATTTATTTATTTTTAGAGACAGGGTTTCTTTCTATGTTCCA
GGCTGGAGTACCATGACACAATCATAGCTTATTGCAGCCTCCAATTCCTAGGCTCAAGCGATTCTCCCCC
CTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCATACCACCAAGCCCAGCTAATTTTTCTTTTATTTTCT
GTAGAGACAGGGTCTCACTACATTGCCCAGGCTAGTCTCGAACTCCTGGCCTCTAGCCATCCCCCCTGCC
TTGGCCTCCCAAAGTGCAGGGATTACAGGCATAAGCCACCACACCTGGCCTACAGAATTGTTAATGGAAA
ATTTAAAGCTTGCAAAACATTGCTCATGTAAACTTACAACAATAAAATTCTTAAGTAATTAAGCATAGAA
GTAGTAATGTCTTAAAAGCCAAACATAGAAAGTGTTTAGAGGAAGAGCAGTCTTTGATGGAAAGAAAACA
GATCATTCTCTACAGAGAAAAAAAAATATTTCTATTTGAGGAAAACAAAAGTCTTCTTTTAAACTGATAG
TCAATATTTTGATCTGTGCAGAGTTTGCAAAAGGATCACATAAGAAACCAAGTAGGGAAATAAACAAAAT
TTTTTGACCTGAGAGTTACTAATGACCATGTATCTACTATGCACTCATCACTTTAAATATGCCATTCCAC
TTAATCTCCTCAACAACTCTCAGTTTTCAGATGAAGAAACAGAAGACCAGAGAGCTTAAGCTACTTGACT
GAGGGCACACAGCTAGTCAGTGGTTCAGTCAAGAGATAAAGAGGCCTGTCCAACATGAACTAACCATTAC
ATACACTACCCCATCCCTTGTGGCAGGAGTCTGAGTGAGGAGAAGAGGAAGAGCCAAGATGAGCACATCA
CGCATGGCCTGGTAATGGGAGTTTCAAATCACTCATGAAAGGAAAGAGAAGAGGAAACTAGAAGTCAGCA
AGCAAAGCTGCAGATGCTCAGGGCTTCAGAGGACAGCTCTGAGTGGAAGAAACAAAATACAGAAACAGGC
TTTCCACTAAGAGTGATTAGCAAAGAGATGATAAGGAAGCAGTCATCACTTGGGGCCTCCCATCAGAAGA
GTGCAAGGAGAATCAAACCGGGCCACAAGCTGTGCGGATGGCCCACTACGGCCTCAAGAGAGAAGAAGAC
AAGTAAGAAACTGGTTTGCAAAATAAGTAACAAATTGGTTTGCAAAATAAAAGTTAACTTAACCATTGAG
AGACAAGCACAATTATGCTTGGAGTAAATTTTGTTTCTCTGGTGGTCCTAGGGAAGTAATTCTCTATTTA
TACACACAGATTTAAAAGTCCAGTTGAACATAGAGGATAAAAAGTTCAAAGAGTCTGTTTTCTATGTGTT
TGTATATTAATATTCTCGCATAACATTTGGGAACCCAGCAGGAGTATTAAATATCTAGCTCTGCCTTTCT
TAGCATTCACTCCAGGTAAGAAGTAACTATAATCTCTGTGCCAGTGTTACCTAGTTAGGCATCTGTAACC
AGCTGCAGGCCACCAACAAGAGGTAATGCAGAGCATCAGAGACAATCTAGACGTCATTCTGCGGATTTGC
CCTAAAACATGAATCACTTTGGAAATGACAAAACCGCCATGGTCTTTGAAATCTTTATTTGCAAGTGTAG
TTTATGAAATGCTAATAAGCTTATACATTTGAAAATATGTCAACATATCTCGATGCAATACTTGGCATCA
TAGATTTGGCAGAGTAAAGGGACCAAAATCTAGACTTTGAGAGACAAGTTAGGATGAGTTCATAGAAATC
CATCGATCCCTTCTATCACCATACTTCTTTCTTACCCTTGCATACCATTCTTTTACCCCACAACACAGTT
TTATTCTTTCCCTGGTGGGCTATAAAAAAAAAAGCCATAGGAATATACTTCTTAAGATAAAATATTCTGC
CACAAATTACTTTTCCTAGCTAAGAAAATGACAGATTTCACATCACTTCTGCATACACACGTATTGAGAT
AAAAACCAAAAATTTTCCATGTCAGAAGAGCAATGGTCTATTGTTCACAAGTGAATCTTAATTATCTCTA
GTCCAATTAAAACTCGGAATCCTTGTGACTATCTGGATAGCATTGACTGCCATGATTAGGCAGCAATTCT
AATGTTTTTCCAAATAAATATAAAGGCATCATTTCTATAAGTTAATCAAGCCATTCAAACAAAGACAGAA
TCAGGGAGAAGAGGCTATTCATCCTGCCTGATTAAGAATTTTTCCACAATAAGAACTGCAGGAATAGGAA
ATGTGATGCAAGCAGAATTATAACAACATTAATTATGTTTGCTGGTTAAAAGAATACATACTCACTGAGA
AAATTTACAAAGTACAAAGAATATTAAAAATCATCTGTCGTTGCCCTATTCAAAGTGAATGTGTGTCTAT
AAGATACAAACTAATCTTCAAAAACCACAGGATGTATCTATGACTTCCCACTGACCTTCTTTTTTTCTTT
TAAGTTCCGGGATACATGTGCAGAATGCTCAGGTTTGTTACACAGGTAAACATGTGCCATGGTGATTTGC
TGCACCTATTAATCCATCTCCTAGGTATTAAGCCCAGCATGCATTAGCTATTTTTCCTGATGCTCTCCTT
CTCCCCAACCCACAGTAGGCCCCAGTGTGTGTTGTTCCCTTCCCTGTGTCTATGTGTTCACATTGTTCAG
CTCCCACTTATAAGTGAGAATGTGTGGCGTTTGGTTTTCTGTTCCTGTGTTAGTTTGCTGAGGATAATGG
CTTCCAGCTCCATCCATGCAGCTGCAAAGGACATGATCAGATTCCTTTTTACGGCTGCATAGCATTCCAT
GGTGTATATGTACCACATTTTTTTTTATCCCACTGACCTTCTATTATGAAAAATGCCTCCACTTTTGCAC
AGCCAAGAACACTGCATGCCTGGCAGGTGTAGAGGCCTTCGTCCTCCTTCCTCACTCTGCGGATAGTGAG
GTTCCGGTTCCCATCCTTCAATACAATGCCTAACAGAGGAAGAAAACGATCATTCTCATTTATGATGATG
TAGTCTGTGAAGTTTTTCAGGGAAATTTAGAAAATATAAATGCTGCCCTTCATCTTGTTCTATTATCTAA
CTCTGTAGAGTCACATGGGATCTACTGCTGACTAATCTCCTATATGGCTTTCATGAAAATTCAACAGGGC
CCCATACTCCAATTCTAAGTCTGTGAAATGAGCCAGGTCATGGACACCAATACTGCTTTTTTTCTACATT
ACATCAAGAAATAATATGGCTTTTTAGATAACATCCCTGGGAAAGTTCTGCAACCCAAGAGTGATAGCCA
AATTCTATTTACCTGAGTCTTCTACAAGGGTCTCATTATCTTTAAACCACATGATCTGTGGAGGGGGATT
CCCAGATGCCGTGCATGAGACTTCGATGCTTTCCCCAATACTTGTCGTCTGATTCTCCAGGTTTCCTGTG
ATCGTGGGTGCCACACGCTCTAGACACACAAAAAGAAAATCACAGAACATGGAATTATAACTTTTGAAAT
GGTTCTGGTATCAGCAAACTTTTAAACAGTTTAAATTTAGTAAAAAGGAACTTGTTGATATATTAACTTC
TGGGAAAATACACTGGTCACTGGGTAAAGTTAAATGAAACAAGTCAGTCAGGACACTGCAAACAGATTAA
TGGCTTTTAACATTCATATTAGTGATACTAGCTGGTAATCCCATCACAAAAGAAAGGTTCAGGGTCACCT
TTATGGATTTTTCCTCTAATTAGACACAGCCTCCCCAGGTGAAAACTTCCCTCCCATGAAGATTCTAGTC
AATAATACCCTAGAATCCCTTCAAATTTCTCTTGGAAGTGCCAAATTTTAGTATCATTCAACCAATAATG
CCTTACATTTATTTGGCAATTCTTATAAAACTTGTTTACACAATTTGTGTTCCTCACTAGTGATCTTATG
TAATGAGCAGAATAGGACTGTTAGCGTTATCTCACAGATGAAATAAATGATGTTCAGCGACATTAAACCA
CTTGTCCATGTCCCTGCAACTAAGTAAACAGTTGAACTGTTTACAGAATCTGGTGAGGCTAAAAGACCAG
TTCAGTGCTATTTCCACTAAAACACAAACAAAACAACAATACCCTAAGGGAAGTCTTGGATTTAAAGAAA
ATGAAGCCCATGAGTATTTGTTTAAGTGTACAAGAACACTTTAGATTTATTCTTTCTTCAGATCATCAAA
GTGCTGTGGAAATATCTTGTCCCAACCAACTGAACATCAAAAGGAATCATGCTGAAAAAATCCACGTCAA
CACTTAGCAAAATGAGATTACCTCAACAGCGTACTACATTGAAGTCTAAGCAAATGTACTGGATTCTAGC
CTATTTCTAAGAATAGGTTTTAGGAAAACAAGTTAGGAGTCCTTAGGGAAGCAAAGCAGCTAACTGCGAG
CACATATTTTCTGGGCACAGCTAGGCCAGGAGCCTACTTCACATCTCTTTCTCAATTCTGCCATAACCTT
GAAGCCAGACAAGCCAACAGAAAATCCATGTGATCTATGTGGTGTGACTTGAAGGATGCTGGGGATGACT
TGACCCCAAAGTATCTCTTATTATGACACCTGAGTCTTAAAACTAGCGAACTTTATGCTAGTGTCTGTCA
GAAGGTGCCTCTTCAAATACGCCAAGGCCTCTGATGAAGACGTTACCCTCTAAAACTGTGGTATAGATGA
ATTTACTTGGGCAATTTCCTTCCTAACAGTAAAAAAAAAACAGAGGGCACATATATCCTAGGAATTGGAA
AGGGACACCACAAGAGGAGAAAATGGAGAGAAGTGGCACAAAGAGACGCTCCCCAAATTTGCCTGATTTT
CCCACAGACAAAGCCATGGCTGCCCAGCTTTTGCACAAGGCATGAGGTTAGACAAGGGGTAGACAGTGCC
TCTATGGAGGAATTTACAGAGCTATCTGCTCACTGAAGTGATCGTCCCATTGACCTTGGGCTACGCTGGA
TCATGTGGGATGACCCAGAGGTACAGACAGTGAATGTAGCTTCCTTCCCATGGAGTCTTCTAGGTCTTAA
ACGCAGCCCATCATCCCACTCTTCATGCAGCAGGTGCCTTATTGAGCAGTTAGTATATGCTGCTATGCTC
TATGACTAGAGCTATAGCAGGGAGCAAAACAGAGAACAATTCCTGTTCTCATGGACACAGAGACCTCACT
GTGCTGTGACTTCCCAGTGGTTGCCTATGTTCTCCTCCTTTCCTTCATGTTTACCACTGTGAATTTCTGA
CACTCTCCTAGCTCATAGCAGGCATTCCACAAATATTTGTCTATTTAAATAAATGGATGCCCAAGATAAG
GCAGAAGTTTCCCTGGTTCAAGCTAATATCCCTTGCATATACTAGTGAATTACTCCATCATCAGGTTTTG
TTATTTTCTCCTTTCGATATATCATTTCATTATTATTAGCTTCTTTCTTCCTCAAGGACTTTCGGTGAAG
AAGTGTGCACCAGTTTACAACATAATCTCCTAGAGGACAGTAATCTTTGCATAGCACCTGAATTGCACTA
CATTTAAGGCATTCCAACTGCCTCTGCACAATGATCCAGAATTGTCTCCCTACCTAGGACTGTGAGCTGC
CTGACCACGCAATGTCTTTTCTTGGTCTTCCTGTCTTGAGCAAGGCAGACATAGTCTCCTTGGTCCTGCA
AGGATGCATTCTTAAGCTCCATGATCAAAATGTCATTTGTGCTATTAGAGAACATGGTGGCATTCAATTT
CCAAAGAGTATCCAAGTTCTTGCAAACAGGTGTGGGCAACTCTCCCACATGGATTGGCAGAGGCTGTGGG
CCAAGCTTGTACCATGTGAGGTTCTCAAACGTAGATCTGTCTGCAGTGCACCACAAAGACACGCTCTCCT
GCTCAGTGGGCTGCATGTCAGGTTGCAAAGTAATTTCAGGACCCCCTAAAATGAAGAGGCCATAGTTATT
GAATGGTGATTTAACTTGGTACAGCTCACTATCATCTTGCTGCTTTCAGACTACTACAAAGTACCAAAAG
AAATGAAGCTCTATCCGTTCCAGGTGATGTACTACAACTTGACAAACAAACTAGACAATTCAGGTCCCAA
AATATCTTATTTGGCCAAACACATTACTTGAAAATGTAAACGAATTCCTCAGATATTTACCACATCTCCA
CTATGAGCTCTACGCAATGTTTAATATATTAAAAATCCAAAGCAAAATCTCTAATTCTAACAGAATTTTA
AAATTAGGTCTTCATTAACACTAACACTCAATGATATGAAAGCTACATTTATGCCAATGAATTAGCCCTG
GCTATAATATTCCATTCAGCACAATCAGCTAAAGCTTATCCATAAAACTAAGATGCACAGGCAAAATCGG
CAGCATTGGGAGGGCACTGCTCCTATGTCCTTCTGATTGCCTCCATAAAGCCCACCCTCATCAACTGTTC
CACAGCAAGCCCACCAATATGTACTGAAGCTCAATAAGCCAGGCACTGTGCCAGACTCTGAAGACTGAGA
TGTAAATACCACACAGAGCTTGTGGTTTAAAGCATCTGTGAAACCATTCTCTCTCCAGTGTAGTTAGACG
CACTGACTTCACATAAGCCCAGGAGATACCTGAGAAGTTGTAATTTATGAATGAAAGCATCAATGATCAA
TCCAAGTCCTCTTTCCTAAATGCCATGCCACTCACATGAATGGCAAAAACAACAGGGAATTACATAGCTT
AGTACCCACTGTGTGAGTGATCCAACCCAAACCTCCAGAGAAGAGTACTTACTGGTCACGTGGAAGGAGA
TCACCCTCTCTCCTCTCCCGACTTTGTTGACCGCTTCACATTTGTACAAAGCTGACACATTTGCCGCTTG
GATAACAAGGGTACTTACAGTCTGTGCGGGGAAAAAACAAATCCCAGGCCATAAACAACGCGGCTGTTTG
TGCACAAGCACTCAGTCCAGCAGTCTCCACAATCACTCCAACCTGCCTATGCCATTCCCACTTCTGCAGC
GGTTGGACACGCTCAAATTTATGCAATTGCAGGTTGAGTATCCCTTACTCAAAACGCTTGGGACCAAAAG
TGGTTTGGATTTTGGATTTTTTTTTTTGGATTTTGGAATATTTGCATTGTATACTTACCAGTTGAGCATC
CCTAATCTGAAAATCCAAAATGCTCCAACGAGCGTTTCCTTTGAGCACCATGTCGGCACTCAAAAAGGTT
CAGAATCTGGAGCATTTTGGATTTGGGGTTTTTAGGTTTGGGATATTTACTCAATTTGTATAATTATGCT
GCTGTGGAGCTCACACATTATATAAAAAGGGCTTTGGAAGCCATGAAACTAATGATGTGTTTTAATATGA
TATGATACACATTTTTTCATTCTCATGTTTATAAAATCAGAATCACCCTACACAGATGCATAGATTTAAT
GTCATAGATGTTTTTATTTTTCTCTGATAAGCTATTAATAAGTTAATGGTACTGCTAAAAGTCAATGGTA
TTTTCAAAGTGACTTAATACGCTCTATTTAATCATCCAGACTATTTGATTATTAATCTCCAATATGCCTC
ACATATTATTGTACCATCCTTCCATTAAAGAGAGAGAGATTTTCAAATTTTAAAACTTCAAACTCACTTT
GTTTTTTCCTTCAATTAGAGCAAATTGATTTTTATTAACTTCAATTTTATTTCCTCCCTGGAAGTCCTCC
ACACTTCTCCATTCTTCACAAGGGTATGGGTTTGTCACTGAGACAGCTTGGCTATAAGAAAGAGATAACA
GCGCATATTATGATTTAATTTTTCTTTAATTAGAGTCAAGAGTAAGGAAAAGATTCAGACTTTGGTTATT
CTGTTCTTAGAAATAACTTCCAACGCAGCCTACCATGGTACAAGACTTGGCGCCAATTAAAAATAGGCAT
TGACAATGAAGGAAAAGGTTCTAGGTAGATTCATTCAGGATACAGGAGGGAAGCAGCTATTCTGGGAATA
AACCTTCATTCATAAATTGGATCGACAAGACAATTCAAGTTAATTTAGTTCAAAGGAAGGCAAGGAAACT
TAGAAGCCACTGGGCTCCTTAAAGTAATTTCTCTGGGACCATGGTCTCTGTGAAGGAAATGATCAGCAGC
TGAGGAAGAAGCTCATAGTGGCCATTTCAAAAACAACAACAGGAAGTGGACTGCTTAGGGTGGTGGTGGG
TTGGCTGCTGTTGTTGTGTTTTTCCCTAAGGATGTCTGGACTTGTGTCAGAGCATGATAAGCTGGGCCTG
AGACCCTGAGGACTGGGGCTGGGTCTATCACTGCCTCTCATCTATCAGCATTTCCTCTGAGAGATGGATC
TTCACACACACAAGAAGGAGGGATGTGGTATTCACCAGCCGATTGGTATCGGGAGAAAAACCAAAGACTG
GCAATTAGCAAACTGAGCAAATAGCCTGTGTTTGGAGAAGTGTACCTCACGGCTAACCTAACAAGGCTGA
GCTTAGCTAACCCCAAAGGAGGATACTCCAAGCAAAGACATCCCCTAAAATGTAAGACACAGAGAAAGAT
GGATGGAGATTCAGGCTACCTCTTGAGAGAAAACTTTTTTTGGTTTAGGCTTCTCCATTTAGGATGGAGT
CATATCATAGCTCAGCTGTAAGAAATGCAAGATGGCAGGAAAGCAAAGAGCATGTGGCCTTACTCACCTG
GGCTCGTTGGCGCACTCTTCCTCCAACTGCCAATACCAGTGGATGTGATGCGGGGGAGGAATGGCATAGA
CCGTACATGTCAGCGTTTGAGTGGTGCCGTACTGGTAGGAATCCACAGGAGAGATTAGAGATTTCTCACC
AATCTGGGGTGGGACTGAAGATGGGAAAAACAACTTTTGAATTGTCAGTCAGCTTTGAAGAATGGGAAAT
AGAGGATTTTAGCAACTAAAGCTGACTTTCTTTAAGCATATGATTTTGCTTCCACTTTCTTTTTCGAAGA
ACACCTAGATGTGGAAACAAGAGACCTGAGTTCTAGTGATACTCATAAAAATAACAACTAGCCAGGCATG
GGGGCTTATGCCTGTAATCTCAGTATTTTGGGACGCCAAGGTAGGTGGATCGCTTAAGCCCAGGAGATCA
AGACCAGCCTGGGCCACATGGTGAGACCCCATCTCTACCAAAAAAAAAAAAAAGGAATAAAGTAACGAAA
TAAAATAAAAATGACAATAAGCTAATAATAATAATAAACTAACAAGCTGAATGACTTTATGGAAGTGTTG
AAATCCTGTGCCTCTCATCTGTATTACAGAGATAGTTCTCTCTGTCCTCTCAAGTTTAGGAGATCAGGGA
AAGGCTACAGAAAACAGCTGAAATAGCACAGTAAATACATTTATTATGTGCCAAGCATTGTTTGAAGTGC
TTTGCATGAATTCATTCACTTAATCCTCACAACCACTATTACTGTCCACAGCTTTATACGTGAGAAAAAA
ATGAAACAGAAAAAAATGACTCGCCCAAGGTCACTCAGTTAACGAACGGCAAAACCTGGAACAAACCTAG
ACACTCTGACTTCTGAACCCAAACACGTAAACCACCTCATGTTAAAGGAAGGTGTAAATCTTTAGAGAAT
GCATTCCTGCCACCATCATCTGAGTTTTTCATTCTCTCTCCCTCTTCCTCCCTCCCTCCCTCTCCACTCC
CTTTCCCTCTTCCCCTTTCTTCCTTCTCCCTTCTCTCACTTCCTTCTTTCTTCTCTCCCTTTTTCCTTTC
TTTCTTTTTTGACTCCAAAGTCAAAACTATTTCCTTATTACTGTCAACCTAAAGCCTCAGATTATGCTTT
GAAGACTTGACTTCTTTTTTATGTTTATTTCATATAGCAGAGAATTTGCTAAAGTGAATAAAATATTTAG
TGGCTTCATGAACTGATGAAATGGGCTATTTGCTGTCCGTGTTTTGTTTTTATTTCCTGTTCATTTCCTC
CTCCCATCCTACTTATACACTTTCCAGTTTCTCCTCTCCCCAGTCCCCTACACCTATGCTGCTTCTAAAC
AACCTTTTTGGAACCTGTTAACTTTTTTTTTGAGACGGAGTTTTGCTCTTGTCACCAGGCTGGAGTACAA
TGGTGCGATCTCGGCTATCTGCAACCTCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAA
GTAGCTGGGATTACAGGTGCCCACCACCATGCCTGGCTAATTTTTATATTTTTAGTAGAGACGGGTTTTC
ATCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCATCCGCCTCGGCCTCCCAAAGTGC
TGGGATTACAGATGCAAACCACGGCACCCAGCCTATCTTTAAAATATTCCCTGAAAAAAAATAATAAAGC
CAAGTTCAGCGGCCTACAGAAGAGTATCAGGACACGTAGGGAAGCACCTTAATGTCATGGGAAAATATCC
TGAAGTTTTAATATGCCGTACCAGAAGGGGGAACAAAGAATTACAACAGAGAAGCATTTCTCAAACTGTT
TGGAGTGAGAGATTAATGAATTTGCTCAGGGGAAAAAAGGTGCTCTGGTCAAATAGGTTTGTTAAACCTT
GAATACTCTATGTCTCTCCTCCTGGAGAATACCAATATACATTAGCATATAAAAGGTTCTGCGAAGTCCT
GCAATAAAGAAACCTGTTACACATCTACACATCACCTTAGCACCTCTCACACTCACTTGACCATGGCACC
CTTCTCCCCACTCCATTCCAAACACTTATTTGTACCTTTCAGTTTCAGAAAACAAAGTTCAAATTATCTT
TACATCAAAAACTTACTATCTTTCCTTTACAGACTCAAAATCAGATCCTGAACTCCTGTCAAAAAGGAAA
AAAGAAAAGCTCCCAACCAAGCCAACAGTGTCAACTTCAAAAGCCTTCAGAGTTGGAACGTGCCTGCACA
TCTCTGATACATCAACTACAACATCAAACTAGAAGCTTTGCACAAAATCTAAGGAGAAGGGTCTTACACA
TCTGTGTACCAGGTGGGCAATTCCATGAGAGGGGAACATGGTAGTATAACTTAGCTTGACAACTGTCCCT
GTGGGCATTCTTATTTCACAACATTTAGCTATCGAGGGTATCACTACTTTAATCTTGCATTTGTCCACCA
CAAAGCTCATTTACACGGCCTCTTAAACAAACATGGCCAGAGCACATGGTCCTACGTTTCACTTCAGCTT
CACCACGCCAGATGACTTTTGTACGCAGGCCCAGCCATGATATGAGTGAAGCAGCAGGAGGCAGAGGAAC
GGTGGTTTGGCTGATTTGGAAGACAATGTATCATAATAAATCTTGGGCAGAGAGGAAAATTGAATGGACT
CACCATACACAACCAGAGAGACCACATGGCTCTGCTTCTCCTTTGAAATGGGATTGGTAAGGATGACAGT
GTAATTTCCTGTGTCTCTTTCACTCACTTCCATAATCGTCAGTACATGCCCCGCTTTAATTGTGTGATTG
GACTCAAGGGGTATTCCATTTTTATACCTATGAAAAAAAATTCTCAGGAATTAGTATAGTCAAAGGATTT
GCTCTCACACGAAATGATGCTTTGCATTTATTTCCAGTAGTTACCATTTTATTTCTGGGGGTGGGTAACC
AAGGTACTTCGCAGGGATTCTGACACGCTCCCCCACCGTGGCTTCCACCAGAGATTCCATGCCACTTCCA
AAAGCAACAAAAGGTTTTTCTGGAAGAAAATAAAAAAAAAAAAAGGTCAACTTACTGTAAATGGTCATTT
GATTTAGTTTTTCATTTCAAGTGAAACGTCAAAGACCTTGAGGGTCTGAGTAGCTGCAGTTCCAAGATTT
CCTGTACTATCTTTCAGTGGGTCACTTTTCAGCTTCTCCCACACCTCCCGTGTTTCTCCCACACCTCCTG
TGTTTGCATTTGCTTTTCTCTCCCCGCTAGTGCACTCCCACAAGCCTAGTGATTGCTCAAGTCTCAACTC
AAACACTTGCTCCTCTGTGCAGCTTTCTCTAAGTCCCCCAGGGATGCTTGGGTGCTCCTTCTCCTCTGCT
CCCATGACAGCCTCCACACACCTCTTCCACCATGAGGCCCCAGGACTCAGTCCTCAGACCTCCTCTTTAT
TTACACCTTCCTCTAGCCTCAGGTTTAAAGTATCATTCACGTACCTCCTAAATGTGTTATCTTCTGCCCT
GACTCCTCTGGGTTCCGGGTTGATATGTTAAATATCTCCACTTGGATGTTTAACAGGCATCTCCAGATAA
ACATATCTAACACTGTTTCCCTAAATCTCACTGCCTTCTCGATCTTTGCCATCTCAGTAAATAACACCAT
CATTTACTCAGTTGCTCATGCTAACGCTCGAGTCATCTTCCACTCTTTTTCTCTTATACTCCACAACCAA
TGAATTGATCAGCGGACCCTGTTGACTCTACCTTCAAAATATATCCAGAAGCAGATCACCTCTCACTACC
TCCACCTCAACTACCCTTGTCTAAGCCACCCCTCAACTCTCACTTGGATAACTGCAATTAGCCTCCCAAC
TGACCTCCTTATTTCTGCCCCTATTTCCCTGAAGTATTCTGGAAAACAAAAGTAATTCTATAAAAACATA
AGCCAGAGCACATCTCTCTCTGTGTATTTTGACAAGTGCATCTTGGCAAGTGAAATAATTTAAATAAATT
TAGGACACTTAGTGATTTCTATTTTGTTCATTCAGAAGAAATTTTCAAGTTCTTGCTAGGGATGCCACGT
GACCTAGAGGTCAAGAGCATAGCTTTGTAGTCAGGAACTTGAGTTCCAATCTCAGCTTCAAAGATGAGAT
GAGCTAATAAAGTAAGTGCTCACTAAATCATACTTGTTATAGTTGTTGCCACTTTTATGATTACAACTCT
AATAAATAGCATTATCTAAGGTATTTTTAAAATTTCACTGTATTGATGCATTCTCATAATATAAACTCCA
AAATCCTTTCCAAGGCTTATAAGTAGGATGCCACACAAATTACCATGTAAACTCAGACATTTATGTAAAT
GAAAGAGAATAAACAAAAAATTAAGGTGATTTTCTCAAGGCCAGTTCAATTTAATTCCAGTTCAATTACA
GTTGACCCTTAAATAACACAAACTTGAACTACATGAGTCCACTTATAAGCAGATTTTCTTCCACCTCTGC
CACCCCTGAGACAGCAAAACCACCCCCTCCTCTTCCCCCTTTTCCTCAGCCTACTCAACGTGAAGACAAG
GATGAAGACCTTTATGATGATCCACTTACACTTAATGAATAGTAAATATATTTTCTCTTCCTTACAATTT
TCTTAATAACATTTTCTTTTCTCTAGCTTTATTGGAAGAATACAGTATATAATACATATAACATATAAAA
TATGTGTTAATTGACTGTTTATGTTATCAGTAGGGCTTCCAGTCAACAGTAGGCCATTAGTTATGTTTTG
TGGAAGTCAAAAGTTATACCTTGATTTTTTTTTTTTTTTTTTTTTTGAGAAGGAGTTTCACTCTTGTTGC
CCAGGCTGGGGTACAATGGCACGATCTTGGCTCACTGCAACCTCCACCTCCTGGGTTCAAGCAATTCTCC
TGCCTCAGCCTCCTGAGTAGCTGGGATTACAAGCTCCCACCACCACACCAGGCTAATTTTTTGGATTTTT
AGTAGAGATGGGGTTCCACCATGTTGACCAGGCTGGTTTCGAACTCCTGATCTCAGGTGATCCACCCACC
TCAGACTCCCAAAGTGTTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTATACATGGATTTTTGACTG
CAGAGGAGGGAAAGTTAGGGGAACTCCCCTGAGTTCCCCCAATCCCTGAGTTGCTCACAGGTCAACTGTA
TATTGCTAAATGTTTCCCCAGTTTGCAAAGCTCATGCTTATTCAAGTAGGCCTCTCAGCCTTGCAATAAA
ATGAAAATTTAAAAACTACCTTAGCTAATACTATTTATCATAGTAACAATCCTAATAGCAGCAATAACTA
TAATAAGTAATACTAAATGAACTCTTACTGTATATCAGCACATCTCATCTTTAAAGTTGAGGTTTGAACC
CAAGTTCCTGACTACAAAGCTATGCTCTTGACCTCTAGGTCATGTGGCCTCCCTAACAAGAAAAACTAGA
AACTATCTTCTGAATGAACAAAATAGGAATCACTAAGTGACCTAAATTTATTTAAATTATCTCACTTGTC
AAGGCACAGAATAATTTCCAAGACCATAGCTTACCATGGACCCTGACAAATGTGCTGTTCTTCTTGGTCA
TCAGCCCACTGGATGCTGCACAGGTGTACAATCCTTGGTCACTCCGGGTTACACCATCTATAGTTAAGGT
GCTCAAAAATTTCTTCATCTCACTCCCAGACTGGGTTTTTAGGTCTCGGTTTACAAGTTTCTTATGCTGA
TGCTGAAAAAAAGAGTTGACTGAACTTCCAAAGCACAGCATATAACATTACCCAATAACTTCTAGTAACA
CACAGAATTAAATCTGGGCTTTGGTAAACATTATTTAATGCTAAAAACAGGGACACCAGAACTTTTAACC
TCATGCAGACAACAAATATATTTTGTTTCAGGAGAAATAAATGGAACCAACTGAATTAGGATTTTTAAAA
CCTCACGTGGTGAAAGTGAGATGGATATAAACTGCAGAAACACAAGTAAATGTGACCACTGTTTAAGGAG
CAGTGTATCTCATGCCACCTCTTAAAGAGAAATTCCCTTAAAAGGAATGTAGATCAAAAACTTTGGAGAA
CAGAGAAATGACATAATGTGGAAAGATGTAATCACCTAGAGAAAACTAATATTCATAGCCTGGCTATTGC
AGAATAGGACAAAATTCCTGGTATTTCACCTTTTGGTGGGTGCTATCTGTTCTGCAATTCCCTTAAATTG
TGTGTGTGTGTATGTGTGTGTGAGTGGGTGTGTATGTGTGTGTGTTTAAGGCTCTTACATTTTATCTGGC
CAAAGAGGCCCCTATCTCTCAAGCAAACTTCACTGGGGCTTATTATCTAAGTATTTGGAGGTCTGGCTTT
GAATCATTAGCGTTACCTTCGAAGAAGGGTATTCCCAGTTGAAGTCAATCCCCACATTTAGTTCAGTTCT
TGCTGTACAATTTAAGACAAGCTTTTCTCCAACAGATAGTTCAATTCCATGAGACGGACTCAGAACCACA
TCATAAATCCTATACCCTAGAGCAAGTAAATTGAAAAAACAGAACATGAGAGAGCAAATAAGCCTATAAC
TTTGCACAGATTTATTTTTTAAAGTAATGCAACTTTAAAACATGCCACATTGTTTTTCCCTGCAGGCCTC
ACCAATACTTGGTAGCTCCCAGGAAAATGGCCAACAGAGGTTTACAAAGCACTACCTTCACAGATCTCAA
AGATGTTGTAACCCAGTGGACAGAAAAGTAGTAAACTTTCAGTGGTCAGTAGCCCTAGGCCAGTAGGGCC
AGCTTTAGCAAATTGCTGAAGTTTCCATAAAATAGTCATAATTGAAATAATTGATAGCAAGCAATGCTCT
GAACATTGAATTCTTCATAAAATGTGCTCGAGTAATACCATTCGCTTTCATCCTTTTTTTAAAAAGTTTT
CTTTTTCTTCCTTAATCTTGGCAAGAAAAGAGACAACCTCAATTGCACATGGGTTTATTTGGTAGAGAAG
AGCAGATGAATTGCCCAACACCATATCCTGAGTTCCTATACTTTTCAATATCCTTCTTCACTCTATGTTG
TTATCTCCAAGATCTTAATACAAGGATATGTTATTAATGATATGGAAAGGAAATGTCCTCTTACCTACAA
CGACAACTATGTACATAATAGACTGGTAACTTTCATCATTAATTTTTGCTTCACAGAAGACCATGCCAGC
ATAGCTGATCATGTAGCTGGGAATAGTAAAGCCCTTCTTGCTGTCCCAGGAAATTCTGTTACCATCAGGA
ACAAATCTCTTTTCTGGGTATCTCTGGGTAATAAAAAGACATATCAAATATTTAATCCAGTACCAAAAAT
GAGAGCCATGTACAATGATCACTGAAGAATTCATCTTATTTTTAAGAATACTAATTAGTTTTATTCATTG
CATTTGACCCTTCCTAAAGGATCCTTAAAACTCATTGTGAATATTATAAACAGGTTACCCATCTTAATAT
TAGCTTAAAATTATAAAAACTTAAGAGACGATTGGAGGAGATGCAACTTACTGCACAAAGTGACACGTTG
AGATTTGAAATGGACCCGAGACATGGAATCACCACAGTTTTGTTTTTGTTCTCAGTAATGTACACGACTC
CATGTTGGTCACTAACAGAAGCAATAAATGGAGATCTGTAATCTAGAAGAAAATTTAGTTTTATTAATGA
GTTAATAGTATTTACTAGAAAAGTTGGTCATTTTTCAGGTTCCTAAACTCTAACCAGACAAGTGAATGAC
TGGAAGGGACACCTCACACAACCAAAGGCATCCACAGATTATTCTGCTGATAGATATCTGTGCTACATGA
GGGTGTGTGTGTATGTGTGTGTGTGTGTTTGTGCATGCACATGCATGTGTATATATCTGTGTGTATAAAA
ATTTTGAAAAAAAACTCCCAATTGAGATTGACTCCTTTCACAAGGTTTATTGACAAGCAGAATATATTTT
TATAGATTTCACATTTTAAAAGATTAATCATTATAATTTTTTCAAAATGAAGGATAATATTTACTTTAAA
ATTTAAAGTTAAATCTATACACTTTACCGACAAGTTTTACTAATATTTAAAATACTCATGTGCTCTCTCT
TTAGGTAAATAATGTAAATTCCATGAAAATAAATGAATGGATCCCAAAGGATCTTTAGATTAACAGGAAA
CAGCTAACACTTTTGAATTTGGTTATTCAAGAGGACCATTCATGTGAGCATTTTAAGATTCTGAAGACTA
GGGATATGATTCTTTCTAAAACCATGTTTAATTGTTTTTGCATTTAGTTTAACATTTAGCAGTCATTGAT
ATCTTCAATGACAAACATTTGAAAAGTCACCACTCCAAAGACTGAGAAGAAAACTGAAGAGATTCTGACT
GGGTTCTTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCTGAGGCAGGTGGATCACTTGAGGTCAGG
AGTTTGAGACCAGCCTGACCAACGTGGCAAAACCCCATCTCTACGAAAAATACAAAAAATTAGCCAGGCA
TGATGGCACGCACCTGTAGTCCCAGCTATTTCAGAGGCTGAGGCAGGAGAATCATTTGAACCGGGGGGCA
GAAGTTGCAGTGAGCTGAGATAGCACCACTGCACTTTAGCCTGGGCAACAAGAGCAAAACTCCGTCTCAA
AAAAAAAAAAAAAAAAAGATTTCAAGGCCAATCAAACATTACTCATACAATGTTAACATGCTGCTGGAAA
CCTAGTCCATTCCTCAGAGATAGAGATGATGTGGTGTGGAGTCATGCTTGAAATCTCAGAGAGATAACAT
TTCACATTGCTATGCCCAACACATCCCATCAAGCATTCTCAGAGTGCTTCATAATAGTCAGTCAAAGTGA
AGAAAGAGTTAATTAAACCACAGGGGACAAAGGCAGCTAATTCCCTGCAACAGCAGAAGTTTGATTTCCT
TCCCAGCTGGAAAGCACAGAAAAGCAGCCAATCTAGCCCACCACATGCCATAGCCATTATCTTATGAGGC
CAGGGCTCACTTCCTGGCTCCATCCATTGCTGAAGAGAATGGGGTCAGAAGACTAGGGAAGTAAGGTGGC
GACCAGAGGGGACATTAAACACCTATCCATAGAGAATACTTCAGTGTTTCCTTTCCCATTGTTTAACTTC
ATGGCCAAAATCTTGGACAGCCCAACTCCTAGAACTTTAAGCTTAGACAGGAAGCAGAATTTAATGGTAT
ACCCAAAGACAGGCAGTGTACCAATAAACAGTGCTAGGGATTGCCACTTCTTAATATTGCCTACCTTTCA
TCCACATGTTATGAAATATTACATAACTTGCTTACAGAGCAAGCCTTTGGAAGCTAAATTAACCCTTTGA
CGTAAGACTAAACCTATTTAGTAAATCAATTCTATTTCGGTATCTCAAAAAAAGGAAATAAACAAAAGAA
ACCCAAACCACCACCCAGCCTCTCAAAATAAAATATTTACTGAAACTCATGAAATGAATTTTCACATGTC
TCCAAGTTTCCTGACTTAGGAAGAAGTAAATAATGAGATATGGGGGATGTTCATCTTGTAGTATTTCTAG
ACAGGCTGAAAGCAGGAAATCCTTGCAATCTTCTGACCGAGCTGCATCTCTCAAGACTGCCAGGTCAAAA
GGAGCCAGAAATTCTCCAAGATGTGAGCCTTGTCTCTTTCAAATCTTGTGGAGGGAAGGAGGAGGGCACA
GAATTCTATCTTTGACAGTGCTTACTCTGGGCAAAGATATTTCTCAAACATTGTGAATCCAGTGGCATAG
GTTATTTTGATGTGGTCTCCACTTTTTCATTGCACTGACCATATTACACTACTGAAATGTAAGCAGAGAT
ATGCAAGTGTGTTTCCCAAAGCTGATGAAATTCTTGCCCTGTAAAAGCTGCTTCTGGGAAAAAAGTCTAA
GTCATCTTCACCTGTCTCAAATACTCTGGGATGTAAAAAGGCATATACGTAAATACATAAAATGTCTGTT
TATCTTCACTGAAAAGAAAAATATTTGGTACATCCAACCAAACTATGATGCAGCCCTTACATTCCTTAAA
TTTATATCATAGGGATCTCATTAGTTAAGTTAGGTTTTCACAGAAAAGATAAGATAGTGTAAGATTTTTG
AAACACAAAAGAATGCATAACTCATTATAAATGCAGAATATGTGTGACATTTATTTTATACTATATGGAT
GTTAAGTCAGCCTTCATAATATCAATCCCAAACTGCACATCCTAGAAAGATACAGCATATCATCCAAGAT
CTCAGACCAAACAAGCAAAGGAAAGAAACATTGTCCTGAAAAGAGTCTGAAGCAATGTCTTTATTTGCAC
ATGAGTATGGGAATTGTTTTTTATGAAATACTAGTAAGAAAAAAAGGTTCCTATGTGCAAAAAACTCCAG
AGCCCTTGGCAAAAAATGCTTTCCTATGCATTCTTGGGAAAATCTCCTACTCTGCTGTAGATAACTTATC
TCTCCACAGAAATTTCTCCATAATTCACCCCCAAATCTTCCTCGATTTCAAGAATTTTAGGTTTTCTTCT
CAAACATAGGAAGACTTTTTATAAGTCTCAATGGCCAACAGTGAACACAGATTTACCTTGGAAACAAAGA
TCAGACCCAAACTAACTGGGCAAAAAAGAGGTAACACGGCCCAAGCTCCAGAATCAATGAGTCTTATTTC
TCAGAGAAAGCCTCAGGAGAGAAGAATTGTGTGTATTCCTCTTGGCAAACAGCCTTTAGAGCAAGCCCTT
TGTTGTACTCAATTCTTCTTTGAGCCTATTGTCTTTTATAACTGGTAAAGAGACGTGGGAAATGAATTTT
ATTTCACCACTTACCTTGAACATAGACATAAATGACCGAGGCCAAGTCAGTTTCCCGGTAGAAGCACTTG
TAGGCTCCAGTGTCATTTCCGATCACTTTTGGAATTGTGAGTGTCTTACAGAAGAGGCCATCGCTGCACT
CAGTCACCTCCACCCTTTGCTCACTGCCACTCTGATTATTGGGCCAAAGCCAGTCCAAGTCCCTCTGTCC
CCTGAAAAATTAATTTCAGGGAGGTATTAATATGAAGTGCCAGACTGTGAGGCTATTTCTAAGAAAAGAG
AAAATTTGGTTTTGAAACTTAAATAAACTCTTCAACAGACACAGTCAGTCTTCTACCGGCCAGGCATGGT
GGCTCATGCCTATAATCCCAGCACTTTGGGAGGCCAAGGCGGATGGATCACCTGAGGCCAGGAGTTCGAG
ACCAGGCTGGGCAACATGGTAAAACCCTGTCTCTACTAAAAATACAAAAATGAGCCAGGTGTGGTGGCGC
ATGCCTGTAATCCCAGCTACTCAGGAGGCTGAGGCATGAGAATTGCTTGAACCCGGGAGGTGGAGGTTGC
AGTGAGCCAAAATCACACCACTGCACTTCAGCCTGGGCAAGAGGGCAACCCTGCCTCAAAAAAAAAAAAA
CAAAGTCTTCTACCAACAAGTCAGATTGACATATGATGAAAAGTTATAAACTCAGCTTCAGAAGTCACTT
ATAAAGATTCCTGAGTTTTCCATTAATTAATGCATTCTTTCTTTCAACAAATATCTATTAAGCATCTACT
ATGTGCCAAACTTGTTAAGGACTAGAGAAAGAGCAGTGAACAAATCAGACAAAAATCAATGCCTTTATGG
AACCTCAGTCTAACTGGAGAAAACAGGCAATTAAAAAGTAAGGAAAGTTTATTGTATAAAAGATAGTGTT
TAGTACTATGGAGAAAAATATAGAAGATACAAAGAAAAGAGTAAAGAATTTTGCAGGAGGTGGTCTTGAT
AAAGCTAGCCATAGGAACATCATGAAGAGCAGTATTACAGGAGCAAAAACAGCACATGGAAAGGCCCTGG
AGCAGGTGCATATCTGGAGTATTAAGGGAACAGCCAGGAAACCAGAGCAGCCAGGTAAGAGTGAGCAAAG
GGGAGTAAGAAGTGAGGTTAGGAAGGAAGGAGGTGCAAGTAAGAGTCCCTCAGGACCTTGTAAGGACCTC
GCATTAAAACATAGATGGCTTGTACTGCAGCATTTCTCTACAAGGCCCCAAGGAAGATAAGAAGATAGTC
AACATCAAGAAGAATGTAACATTATTGGCCCTTCATTCAAAGAACTTAAAATTTCCAGGAAGTTGCAGCT
AAATCAATGAAGTTACTTTTAACACACTCCATGGTTTTTTTCAGAACATAAGAAATGTTTATGCAGAGTT
TTAAAAAGGGAGCATGGGATCCTTGGGGATTTCAAATAACCTTGTTATCGAGGGTCGGTAAAAGGAAAAT
CTAATGGGAAATGTGTCTTAAACAAGTAAAGCTAGAGAAACAGCACCTGCTACTGTGTTTTTTCCCAAGG
GCTGGGTATTGGTAAGGGGCTAGGGTATTCTTTATACTGCAGTCTAAAATAGATGTATGTCATTCGGTTT
AATGCTTAGTATTCAACAAGTATGAAGCAATGGCAATAACCTACCCAAGGTCCTTTGTGGACCCCCAGCA
CTCTTCCAGGAGGGTAACATCACCTCCACTTGTCACAGTCTCTACCAAAAACACACAGGTCCTAAGAAGG
CTCCATGCCTTTCGTGTGTGATCACTATGTTAAACCCAAGGGTCTTCTATCTTTCGTCCTGGGGTAAGGG
TTGAAAGGCAAAATTTAAAGGCCTCTTCTTCTTGACAAAGAAGTCTACTTCTCCAGTTATCAAAAATCAA
TAGCATGACTTCTTGCTAGCAAGTGGGGAAAGATGCATTCCAGAATATCAAGGCAGGGCCCGAAGTCCAT
TATTTATGTAGATCATGCGCTCAGTAATATTACCCACTAAATATTAAATTGCTATTAAATATTACTGCCT
AAGTAATTATAGTAATAAATTTCTTATAAAGCAAAGTTTTTGGAAAGGGATAATAAGTGTTCAAGAATCA
TACCAAGCATAATAAATATAGTCCCAAATTTTTTCAACTCTATTCCTTAAATGTATGCCCTCAACTTCAT
TTATTCATTCATATTTATTGAGCGTATGTCTACTATACGCCAGGTGGCTGTACTGGTTATTGGAATGTGG
GTGTGGGTGTGTATTTGTGTGCGTGTGTGTGTGTGTGTGTGTATGCATGTTGGCAGAGAATAGTATAAAA
ACACCAGCAAAATTGTACAGAATTTTTGAGAGAAAATTCTTCTCATTTTCCATTATTACATCAGTTCTTA
GAAACCTCACCACTTATGAACAATTACTACAAGCTCTATTATAATTCTGCTCTACTGGAAATTATTTCCA
CTCAATAAACAATCAGTTACTTAACACAAGAAATCTAGATCTAGAATGAATCCTTACCTGCAAGTAATTT
GAAGAGTTGTATTAGCCTTAATTGTAAGTATGTCTTTTTGTATGCTGAGCCTGGGCAGATCAAGAGAAAC
ACTAGGCAAACCTAGAAACAAATTAAATAAATGAATGTAGTTGCCACTGAGTTAGACCTAATAGGAAACA
CCTTCCATAAACAATGCATACTCTATACTTTAAAAGGCCTCTTCAGCAATTCATTGTATAAAACTGGGAA
TTTACTTTTCACCATTCTCAGTAAAAGTTCACAAGCTGTGTCATAACAGGAAGAATGGGCAGATGGTCAT
AAACCAACACAACAGTTCTGCAATTCATGGAGCTAGGGTGGAGTTCCTGTTTTCCTGCATTGCCAACTTC
AAGGTCTTACAAAAGGATACGGGACATTGAAACCAAATGAACCTTCATCTGATGATCTCACTCCCTTGGG
AAAGGACCCACTGACATTTCTTATAGAACATAGGATGTACACATTTGACTAAATTGCTGATTAACGAATC
CCACTTAGACGGATTTTTATATAGTTCATCTACGTACCCTGAAGGGAGTGAGAGAATCTATGACCTTGTC
TCATTTTCCTTTATCAATTTTCTAGTGCGCTTCCCCTGGTAACCAAACTGCCACAGCTGAAATAATGGCT
CATAAAGACTGTACATTAAAAGCAAGGGAGAGAAACTGAGGAAGAGAAAACATTCCCCAATTCCACACAT
ACATGCATATTAATATACTTTTATGTATGTGTGGAATTTTCCCAATTTTACACATATGTGCAAATTAATA
TACTTTTCTGTCTACTGTAATTCATTAGCATTACCCTTTTTTTAAAAAGTATATGAATATTTTCGTGAAA
AATTTTCCCAGTTTCACACATACATGCAAACTAATGTACTTTTCTCTCTATTGTAATTCATTAGCATTAC
CCTTTTTTAAAAACGTATATAAATTTTTTTAAGTGCAATGCTAATGAATTACAATTGGGAGATCTGAACT
TATTCATCAAAGCCCTGAACTCATCCTGACATCAAGCTTCAGACATAAGAAACTTGTCTTTACCTATAAG
GGATAAGAACCAGAAAAGTACCATGGCATAGATTCCTCACCATGGGTCACTCTACAGCAAGATAACTGAA
TTCTCTGTCAACTAAATGTGAAGAGCTATGAGGTGTTGAAAAAGCATGAGAGAAAGAAAAATTGTCCACT
ATGCTAGGGTCTTAATAAATATCAAGACCTAGAAAATACCAGCTTTAAAAAAGTAATTGATGTTGGGCAG
GCTCCCAAGCTTTCTAAGTCATATCAACTAAGAAAAAATGACTCCCTAGGCCTAAACTGGCATTGACCTT
GCTGGGCAAATAAGAGAGTATGAACAAATAGGACGAAGTATGAGACGGAATAAATAGAGAGAGTATAAGT
AAATACCCAGTGCAAACATCCAGTGCATTGAATCTGAGGATCCCAATATGAACAAATGCAGGCAAAATGA
ATAAGTGACTGCACATGTTCTCACACACCACACAGATGTGCAAAATAAGTTACTGACATAACTGGTCAAT
ATCATGGTTTTTAAGTCAATAATATGGTTTTTAAAAAACTGGAAACTAAGTTATATCAATATATCTCAGA
AATTAACTGGCATTGGTACTGACTTATGTTTAGAACAGTTTTGTTCTTAAGACTTTAGACTCTGTCAGAA
TATCCCTGGGTCTACAAATCTGCATTTTAACAAGCATTTCAAATTATCCTACCACAGATGGTCTATGGGC
CACTCTTGGACAGTTGCTGGTCTGGGTGGTCATGTTTAATTAATTTGCACAGTACTTTGTGCGTGGAACG
GGGGTTACATTTATGTTTTAAATAGAGAATGGGGTCTCGCTATGTTGCCCAGGCACTTCTTGAACTCCTG
GACTCAAGCGATCCTCCTGCCTCTGCTTCCCTAAGTGCTGGGATTACAGGAATGAGCCACTGCACCCAGC
CTGCACAGTACTTTTTAATATGAAAGAAATAACTGCCCCCAAAACAGGCAAACAAAAAACCAAAATGTTT
AAAAGCAAAATGAAACCTGGAGTCCCACTTTGTCTAAGAAAAGGAAAATGAAAACAATTCATTTGGATAA
CACAGATTTCAAACTTGACTGGGGAACACTAGGTTGAGAAAGATGCTGAAAACATGATGTACAATTCACA
CTGCCATCCAAATGAGAAAAAAACCATTATTTGGGCACATTCTTGTGAGAAAACAAATGGCAGTAAAAAT
GATTCTCAATAAACTGTGCCCACTCGGCTACCAAAATCAGAAACTCTTGAAGGTCTCTCATAATTTATTG
CCACAGATCACATTCTAGACACACTTTCCTGTGTAACAAATATTTTAAAAAAGAAAAGGTATGTCCTTCA
TTCATAGGAAGCTGAGACTATGCCATACTATTCTAGAGACACGTTTACAACAAAAATCTATTCAACAAGG
CTCTCAATAACTTCAAATTCATATTTGTAGACCAACATAGTTTTTTGTTTTTTGTTTTTGCTCCATTAAA
TGTCATTCGTTTTCATTGGCAAGCTTGAGCTGGACTCTTCAGAAAGTTCTAAAGAAATAACTGTAAGAGG
TACACATGCTACTACTCAATAAAAAGCCCTTCTATGTTCAAATCCCATAACCAATATTAATTAATTTGTG
CACTGTTACCCTTCCAGCTCAAAGACGGGAAGGAAAAACAACAGTGCCTCTGTCTCTAGAATTTGATGGC
ACCAATTACAGCCCAATCCAATTAAGCAAGTAATGCACTCCAAAAGGGCAAGTTCACCATTATATTCAGG
GCGACCGGCCTGCCGTTACTACTACGCTAGGAAACACCCCAGGCTTAAAAGCAACTCACTTCTTTGTGGA
ATACAGAGCAACCACATGTTCCAGACCTTCATTCTCTGCCCAGAAAGGGGGAGAGAGAGGGCTTGTCTGG
GACAAATGAGTGTCCATGGTGGACTGGACCCGTTGAACCAAGTCATTATAAAGAAAATTCAGTAACCATG
GACAGATGATCCTGGTACTGTATGTGGGTGTGAGTGTCTTCTAAGACATGTGATTCTTGTCTTAGGGAGT
AAGAAATTTTTTTCCCTGAATTATTCGACTTTTTTTTTTTCTTTCTCTGACCCTTTCCCCTTTCTCACCC
TGCAAAGGGTGGAAATCTGGATATCAGCAAACTGGCTGCAGGAAAGAAATATTATCTAAGGGGTTGAGAG
AGAAAGGAAAGTGAGGAAGAAAAGACAGACAGCTATTGCATGAAGAACGTGTGTGTTCCTAATTGAAGGA
GACGGAAATTTTAGGCGGCAGGGAGAGGAAGGAATGGCACTAAAGCTAGGTACCAAGGCCCACAGGAAAG
GTTTTCGGAGCTTGAACTTCTGACTATGCGCTTACACCAAGGACCACAGCGCTTTGAAAGATGTGCAATG
CTTTACGCAGGACAGTTGGCTGTTACTTGGAGACCCTTGGGGAAGCTGTCAAAGCCCCCAGGACAAGTCC
CTATTCCCCCCCTTCTTCGCTCTGCAAGGAGAGCGGCGTCCTGCACCAAGGAAGGAAAAAAAGTTTCTCT
CCGCTCCAGACCCCACTTCACACAGTGGTGTGCAAGTGTGTTCGAGCATGAAGACAACAACGGGCCGGGT
CCCGCAAAGAGGCAGAACCGAGTGTACCGTCCGATCCGGGAGACCCGGCCTGAGATTCCGGCAAGGTTTT
CTTCCCCGGGCCCGGACTAGGATGTTGCGCGCAGCCAGACAACTTTTCACCGCCTGTTCTCGCCTGCGGA
GGCACCTCCTGCCTGCCAACCCCAGGCGCCTTCCCACCCCAGCCTCCCAAGAGCCTGAGGGTGTGTCGGC
ATCTCAGGACATGCTCCAGCCGAGGTCCCTGTCGCAAACCAGAGTCCTAGAAAAGGAACTGGGCTAGAGC
ACAGGCGACCACAGACTCGCTGGGTAATCTTGGGCCAGTCTCTGAGCCTCAGTTTCCCCACTGGTAAATG
AAAGATCGCAAAATGTCAAGTCCTGTCCAACTCTCCAGCTCTACGATTCCGAGTTAGATCTGGCTTTCAG
GTCCTCTCCGCCCTCACCCGACCTGTCTGCCTTCCTCCTCCAGAGTGGGCTCCTTACCCACAGAGGCGGC
CCGGGTCTCCACGCAGAGCCACAGGGCGACGGCCAGCAGCACCTTGCTCTGCATCCTGCACCTCGAGCCG
GGCGAAATGCCCAGAACTCGGGAGCCGGTTCTTTCTCCCAGCGCCTGTCTAGAGAAGGAGGCGCGGAGGT
GGAACTCGCGGCACCCCGCAGCGCAGGACAGTTGAGCGCACAGGGCTAGGGAGCCCGGGCGCCGACCGCG
GCTGCAGGGGCGTCTGCGGGTGCCGGTAGGAGAGGATATCCAGGCTGCCAGACGGACTTTCTGCGGCGCG
CAAGTGATGCCCGGCGCAGGCAGAGGAAACGCAGCGACCACACATTGACCGCTCTCCCGGGGTCCCGGGA
CTCAG

Protein Sequence
>NP_002244.1 vascular endothelial growth factor receptor 2 precursor [Homo sapiens]
MQSKVLLAVALWLCVETRAASVGLPSVSLDLPRLSIQKDILTIKANTTLQITCRGQRDLDWLWPNNQSGS
EQRVEVTECSDGLFCKTLTIPKVIGNDTGAYKCFYRETDLASVIYVYVQDYRSPFIASVSDQHGVVYITE
NKNKTVVIPCLGSISNLNVSLCARYPEKRFVPDGNRISWDSKKGFTIPSYMISYAGMVFCEAKINDESYQ
SIMYIVVVVGYRIYDVVLSPSHGIELSVGEKLVLNCTARTELNVGIDFNWEYPSSKHQHKKLVNRDLKTQ
SGSEMKKFLSTLTIDGVTRSDQGLYTCAASSGLMTKKNSTFVRVHEKPFVAFGSGMESLVEATVGERVRI
PAKYLGYPPPEIKWYKNGIPLESNHTIKAGHVLTIMEVSERDTGNYTVILTNPISKEKQSHVVSLVVYVP
PQIGEKSLISPVDSYQYGTTQTLTCTVYAIPPPHHIHWYWQLEEECANEPSQAVSVTNPYPCEEWRSVED
FQGGNKIEVNKNQFALIEGKNKTVSTLVIQAANVSALYKCEAVNKVGRGERVISFHVTRGPEITLQPDMQ
PTEQESVSLWCTADRSTFENLTWYKLGPQPLPIHVGELPTPVCKNLDTLWKLNATMFSNSTNDILIMELK
NASLQDQGDYVCLAQDRKTKKRHCVVRQLTVLERVAPTITGNLENQTTSIGESIEVSCTASGNPPPQIMW
FKDNETLVEDSGIVLKDGNRNLTIRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQEKTNLEIIILVG
TAVIAMFFWLLLVIILRTVKRANGGELKTGYLSIVMDPDELPLDEHCERLPYDASKWEFPRDRLKLGKPL
GRGAFGQVIEADAFGIDKTATCRTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLLGACTKPGG
PLMVIVEFCKFGNLSTYLRSKRNEFVPYKTKGARFRQGKDYVGAIPVDLKRRLDSITSSQSSASSGFVEE
KSLSDVEEEEAPEDLYKDFLTLEHLICYSFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLA
RDIYKDPDYVRKGDARLPLKWMAPETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLK
EGTRMRAPDYTTPEMYQTMLDCWHGEPSQRPTFSELVEHLGNLLQANAQQDGKDYIVLPISETLSMEEDS
GLSLPTSPVSCMEEEEVCDPKFHYDNTAGISQYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDNQTDS
GMVLASEELKTLEDRTKLSPSFGGMVPSKSRESVASEGSNQTSGYQSGYHSDDTDTTVYSSEEAELLKLI
EIGVQTGSTAQILQPDSGTTLSSPPV

Molecule Role Protective antigen
Molecule Role Annotation Targeting a central cell type involved in angiogenesis, endothelial cells, we immunized FVB/N mice against host vascular endothelial growth factor receptor 2 (VEGFR2) to fight the growth of Her-2/neu(+) breast tumors. Using the bacterial vector, Listeria monocytogenes (Lm), polypeptides from the mouse vascular endothelial growth factor receptor 2 molecule (fetal liver kinase-1) were fused to the microbial adjuvant, listeriolysin-O, and used Lm to deliver the Ags and elicit potent antitumor CTL responses. Lm-listeriolysin-O-fetal liver kinase-1 was able to eradicate some established breast tumors, reduce microvascular density in the remaining tumors, protect against tumor rechallenge and experimental metastases, and induce epitope spreading to various regions of the tumor-associated Ag Her-2/neu. Tumor eradication was found to be dependent on epitope spreading to HER-2/neu and was not solely due to the reduction of tumor vasculature (Seavey et al., 2009).
Related Vaccines(s) HLA-A*0201-Restricted URLC10-VEGFR1-VEGFR2 Multipeptide Vaccine , HLA-A*0201-Restricted VEGFR1 Peptide Vaccine , HLA-A*2402-Restricted VEGFR1 Peptide Vaccine , HLA-A*2402-Restricted VEGFR1/2 Multipeptide Vaccine , HLA-A*2404-Restricted RNF43-TOMM34-VEGFR1-VEGFR2 Multipeptide Vaccine , Live-attenuated Double-deleted Listeria monocytogenes Bacteria JNJ-64041809 Vaccine , LY6K/VEGFR1/VEGFR2 Multipeptide Vaccine , VEGFR-2 DNA Vaccine VXM01
References