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LPS lipopolysaccharide

Gene Name LPS lipopolysaccharide
Sequence Strain (Species/Organism) Brucella ovis
Molecule Role Protective antigen
Molecule Role Annotation The adjuvant and protective capacity against anaphylactic shock of the association between rough lipopolysaccharide of Brucella ovis (LPS) coencapsulated with ovalbumin (OVA), as a model allergen, in Gantrez AN nanoparticles was investigated. In a model of sensitized mice to OVA, the formulation with OVA and LPS-entrapped inside the nanoparticles administered intradermally in three doses of 3 microg of OVA each was the only treatment that totally protected the mice from death after a challenge with an intraperitoneal injection of OVA (Gómez et al., 2008).
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