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Bfr from B. abortus S19

Gene Name Bfr from B. abortus S19
Sequence Strain (Species/Organism) Brucella abortus S19
VO ID VO_0010907
NCBI Gene ID 6326162
NCBI Protein GI 189022832
Locus Tag BAbS19_II06320
Genbank Accession CP000888
Protein Accession YP_001932573
Taxonomy ID 430066
Chromosome No 2
Gene Starting Position 673149
Gene Ending Position 673634
Gene Strand (Orientation) -
Protein Name Bacterioferritin
Protein pI 4.42
Protein Weight 17971.98
Protein Length 161
DNA Sequence 
>NC_010740.1:673149-673634 Brucella abortus S19 chromosome 2, complete sequence
CTTACTCAGCTTCGTCGGCGGGCGCCGCGTTAAGCTGGCCATAGCGTTCTCCGCCGATCTTGGCGAGAAG
GTCAAGCTGGGTTTCAAGGAAGTCGATATGGCCTTCTTCATCGGCCAGAAGTTCGTCGAAAAGCTGCTTC
GACACATAGTCGCCGAGCTTGTCGCAGATTTCGCGCGATTCCTTATACGAAGCGCGAGCGTCATATTCAC
CCTTGAGGTCAGCTTCGAGAACTTCCTTCACATTCTGGCCAATGCGCAACGGCGAAACGGTCTGGAGGTT
CGGAAAGCCTTCAAGGAAGATAATGCGATCAATCAGCTTGTCGGCGTGATGCATTTCCTCGATGGATTCC
TCGCGTTCCTTCTTTGCAAGGCGCGTGTAACCCCAATCGTTGAGAAGACGGTAGTGCAGCCAATACTGGT
TTACCGCACCGAGCTCAAGAAACAGTGCCTCGTTAAGCCGCTCGATGACCTTTGGTTCGCCTTTCA
Protein Sequence 
>YP_001932573.1 Bacterioferritin [Brucella abortus S19]
MKGEPKVIERLNEALFLELGAVNQYWLHYRLLNDWGYTRLAKKEREESIEEMHHADKLIDRIIFLEGFPN
LQTVSPLRIGQNVKEVLEADLKGEYDARASYKESREICDKLGDYVSKQLFDELLADEEGHIDFLETQLDL
LAKIGGERYGQLNAAPADEAE
Molecule Role Protective antigen
Molecule Role Annotation Following two intragastric immunizations in BALB/c mice, the Yersinia vectors harboring a DNA vaccine encoding BFR (P39) induced antigen-specific serum immunoglobulin and Th1-type responses among splenocytes. The best protection was conferred by a serotype O:9 strain carrying pCIP39, confirming the importance of the P39 T-cell antigen in this mechanism (Al-Mariri et al., 2002).
References