VIOLIN: Vaccine Investigation and Online Information Network

VP6
Gene Name	VP6
Sequence Strain (Species/Organism)	Bovine rotavirus
VO ID	VO_0011258
NCBI Protein GI	195661002
3D structure: PDB ID	1QHD
Other Database IDs	CDD:279341
Taxonomy ID	10927
Gene Strand (Orientation)	?
Protein Name	VP6
Protein pI	5.72
Protein Weight	42501.43
Protein Length	439
Protein Note	Rotavirus major capsid protein VP6; pfam00980
Protein Sequence	>ACG50679.1 VP6 [Bovine rotavirus] MDVLYSLSKTLKDARDKIVEGTLYSNVSDLIQQFNQMIITMNGNEFQTGGIGNLPIRNWNFDFGLLGTTL LNLDANYVETARNTIDYFVDFVDNVCIDEMVRESQRNGIAPQSDSLRKLSGIKFKRINFDNSSEYIENWN LQNRRQRTGFTFHKPNIFPYSASFTLNRSQPAHDNLMGTMWLNAGSEIQVAGFDYSCAINAPANTQQFEH VVQLRRVLTTATITLLPDAERFSFPRVINSADGATTWYFNPVILRPNNVEVEFLLNGQIINTYQARFGTI IARNFDTIRLSFQLMRPPNMTPAVAALFPNAQPFEHHATVGLTLRIESAVCESVLADASETMLANVTSVR QEYAIPVGPVFPPGMNWTDLITNYSPSREDNLQRVFTVASIRSMLVK
Molecule Role	Protective antigen
Molecule Role Annotation	Rotavirus structural proteins VP4, VP6 and VP7 from Bovine Rotavirus Strain C486 were cloned and expressed in a baculovirus expression system. Challenge of neonates born to animals immunized with VP6 protein showed partial protection (Redmond et al., 1993).
Related Vaccines(s)	Rotavirus VP4/VP7 Protein Vaccine
References