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E

Gene Name E
Sequence Strain (Species/Organism) Yellow fever virus Senegal/Ko/HD117294/1995
VO ID VO_0011252
NCBI Protein GI 262283879
Other Database IDs CDD:279241
CDD:280922
CDD:213897
Taxonomy ID 11089
Gene Strand (Orientation) ?
Protein Name envelope glycoprotein
Protein pI 6.44
Protein Weight 50896.68
Protein Length 580
Protein Note Flavivirus glycoprotein, central and dimerization domains; pfam00869
Protein Sequence 
>ACY40747.1 envelope glycoprotein, partial [Yellow fever virus]
VGPAYSAHCIGITDRDFIEGVHGGTWVSATLEQDKCVTVMAPDKPSLDISLETVAIDGPAEARKVCYNAV
LTHVKINDKCPSTGEAHLAEENEGDNACKRTYSDRGWGNGCGLFGKGSIVACAKFTCAKSMSLFEVDQTK
IQYVIRAQLHVGAKQENWNTDIKTLKFDALSGSQEAEFTGYGKATLECQVQTAVDFGNSYIAEMEKESWI
VDRQWAQDLTLPWQSGSGGVWREMHHLVEFEPPHAATIRVLALGNQEGSLKTALTGAMRVTKDTNDNNLY
KLHGGHVSCRVKLSALTLKGTSYKMCTDKMSFVKNPTDTGHGTVVMQVKVPKGAPCKIPVIVADDLTAAI
NKGILVTVNPIASTNDDEVLIEVNPPFGDSYIIVGTGDSRLTYQWHKEGSSIGKLFTQTMKGAERLAVMG
DAAWDFSSAGGFFTSVGKGIHTVFGSAFQGLFGGLSWITKVIMGAVLIWVGINTRNMTMSMSMILVGVIM
MFLSLGVGADQGCAINF
Molecule Role Protective antigen
Molecule Role Annotation A recombinant, vP869, expressing prM and E induced high titers of neutralizing and hemagglutination inhibiting antibodies in mice and was protective against intracranial challenge with the French neurotropic strain of YFV (Pincus et al., 1992).
Related Vaccines(s) vP869
References