VIOLIN: Vaccine Investigation and Online Information Network

G
Gene Name	G
Sequence Strain (Species/Organism)	Rabies virus
VO ID	VO_0011231
NCBI Protein GI	56384945
Other Database IDs	CDD:279337
Taxonomy ID	11292
Gene Strand (Orientation)	?
Protein Name	glycoprotein
Protein pI	7.66
Protein Weight	55317.81
Protein Length	578
Protein Note	Rhabdovirus spike glycoprotein; pfam00974
Protein Sequence	>AAV85905.1 glycoprotein [Rabies lyssavirus] MVPQALLFVPFLGFSLCFGKFPIYTIPDKLGPWSPIDIHHLSCPNNLVVEDEGCTNLSGFSYLELKVGHI SAIKVNGFTCTGVVTEAETYTNFVGYVTTTFKRKHFRPTPDACRAAYNWKTAGDPRYEESLQNPYPDYQW LRTVRTTKESLVIISPSAADLDPYDKSLHSRVFPSGKCSGITVSSVYCSTNHDYTIWMPENPRQGMSCDI FTNSRGKRASKERKTCGFVDERGLYKSLRGSCKLKLCGVLGLRLMDGTWVAMQTSNETKWCSPDQLVNLH DFHSDEIEHLVVEELVKKREECLDALESIMTTKSVSFRRLSHLRKLVPGFGKAYTIINKTLMEAEAHYKS VRTWNEIVPSKGCLRVEGRCHPHVNGVFFNGIILGPDGHVLIPEMQSSLLQQHMELLESSVIPLMHPLAD PSTVFKEGDEAEDFVEVHFPDVHKKVSEVDLGLPNWGEYVLLSAGTLIALMLIIFLMICRRRVNRPESTQ RSLRGTEMKVSVTPQSGKFKSSWESYKSGDEARL
Molecule Role	Protective antigen
Molecule Role Annotation	A DNA vaccine based on lysosome-targeted glycoprotein of the rabies virus was evaluated in BALB/c mice. It imparted partial protection (60%) against challenge with 20 LD(50) of the challenge virus standard (CVS) strain of rabies virus (Kaur et al., 2010).
Related Vaccines(s)	AdC68- rabies virus glycoprotein , Rabies DNA Vaccine encoding Rabies virus Glycoprotein , Rabies virus DNA vaccine pCMV-intA-rabies encoding glycoprotein G , Rabies Virus Vaccine pAlpha-Rab-G
References