VIOLIN: Vaccine Investigation and Online Information Network

Mpt63
Gene Name	Mpt63
Sequence Strain (Species/Organism)	Mycobacterium tuberculosis H37Rv
VO ID	VO_0011176
NCBI Gene ID	885334
NCBI Protein GI	15609063
Locus Tag	Rv1926c
Genbank Accession	AL123456
Protein Accession	NP_216442
3D structure: PDB ID	1LMI
Taxonomy ID	83332
Gene Starting Position	2178956
Gene Ending Position	2179435
Gene Strand (Orientation)	-
Protein Name	immunogenic protein Mpt63
Protein pI	4.67
Protein Weight	14827.76
Protein Length	159
Protein Note	Rv1926c, (MT1977, MTCY09F9.38), len: 159 aa. mpt63 (alternate gene name: mpb63), immunogenic protein (see citations below), identical to MPT63\|MPB63 from Mycobacterium bovis (159 aa). Exported protein containing a N-terminal signal sequence: see notes below about proteomics.; mpb63
DNA Sequence	>NC_000962.3:2178956-2179435 Mycobacterium tuberculosis H37Rv, complete genome TCTACGGCTCCCAAATCAGCAGATCCTCCATGCCGTTGTTCATCGCGACGATGGTTGGCGATGGGCCGGT GACATCGAAGTAGATTTTGCCGGTCGATTGTTCGCCTTGGGGGATAGTGGCTCCGCTAATGGTGTCGGGG CCCGCGGCTTGCCACAGCACCCGGTAGTTGATGCCGTCGGCGGTGCGGGCATTGAACTGCGAGACCGCGG GCGTGACGCTGCCGCGAATCGCATTGACCGTGGCAGTGGCCTCCCAGACCTGGCCGGCCACCGGATAGCC GGGGATGACTGCCGTGCTGGATTTGAGATCACTGACCTTCCAGCCGAGCACGACTTGGCCAACGGTGTCG GTCATCGTTAGCTCACTGCCAAGTTTTCCGGTGATGGGATAGGCAGCCAACGCGACCGGTGCCGCAAAGG TCGCGATGGCCGCCATGGCCACGACCGCTACTGCCGTCTTGATCATTGTGGTGAGCTTCA
Protein Sequence	>NP_216442.1 immunogenic protein Mpt63 [Mycobacterium tuberculosis H37Rv] MKLTTMIKTAVAVVAMAAIATFAAPVALAAYPITGKLGSELTMTDTVGQVVLGWKVSDLKSSTAVIPGYP VAGQVWEATATVNAIRGSVTPAVSQFNARTADGINYRVLWQAAGPDTISGATIPQGEQSTGKIYFDVTGP SPTIVAMNNGMEDLLIWEP
Molecule Role	Protective antigen
Molecule Role Annotation	MPT63 (Rv1926c), a major secreted protein of Mycobacterium tuberculosis, is immunoreactive in antibody assays in humans and animals and provides protection as a combined DNA vaccine in mice (Mustafa, 2009).
References

Mpt63