VIOLIN: Vaccine Investigation and Online Information Network

ORFF
Gene Name	ORFF
Sequence Strain (Species/Organism)	Leishmania donovani
VO ID	VO_0011159
NCBI Protein GI	703122
Taxonomy ID	5661
Gene Strand (Orientation)	?
Protein Name	unknown
Protein pI	5.32
Protein Weight	29594.74
Protein Length	334
Protein Sequence	>AAA96728.1 unknown [Leishmania donovani] MQSDARELNPGRADFWEHFYGQEDGRLQQKELHHRKAREIVERGSLMNHYEWFMQYPMYEAALKACLRAV PTVLSKDGATRILHTGCGNSDFCDHVEGLLSDLNPAPSSSSRTCEVLNVDICENIVTHLALHFPSRLYAV GDCCDLHVSSSPSMPFSSNAAWYSRDTALRLRTVLQSSVDVVFDKGTADALLSSFAGVCNPNMEAYVGEA LKVLRPGGLLFLISINSEDVLSPYVLSAGDGLKSFQLAYADVIELCAQDLRHLRVETLGSRYSCYGYAVV ASAVAE
Molecule Role	Protective antigen
Molecule Role Annotation	An expression plasmid encoding both p35 and p40 subunits of IL-12 when co-administered with a recombinant open-reading frame (rORFF) gene from the LD1 locus of Leishmania donovani induces significant protection with around 82% protection in both liver and spleen of BALB/c mice when challenged with L. donovani (Tewary et al., 2006).
Related Vaccines(s)	L. donovani ORFF Protein Vaccine
References