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A2

Gene Name A2
Sequence Strain (Species/Organism) Leishmania donovani
VO ID VO_0011153
NCBI Protein GI 30385439
Taxonomy ID 5671
Gene Strand (Orientation) ?
Protein Name stage-specific S antigen-like protein
Protein pI 4.19
Protein Weight 9285.64
Protein Length 194
Protein Note zymodeme MON-29
Protein Sequence
>AAP21105.1 stage-specific S antigen-like protein [Leishmania infantum]
MKIRSVRPLVVLLVCVAAVLALSASAEPHKAAVDAGPLSVDVGPLSVDVGPLSVGPQSVGPLSVGPQSVD
PLSVDVGPLSVGPQSVGPLSVDVGPLSVGPQSVGPLSVGLQAVDVSPVS

Molecule Role Protective antigen
Molecule Role Annotation Study results show that a single intraperitoneal administration of the A2-recombinant L. tarentolae strain expressing the Leishmania donovani A2 antigen protects BALB/c mice against L. infantum challenge and that protective immunity is associated with high levels of IFN-gamma production prior and after challenge (Mizbani et al., 2009).
Related Vaccines(s) Leishmania vaccine using recombinant L. tarentolae strain expressing A2 antigen
References